Multistage-responsive nanovehicle to improve tumor penetration for dual-modality imaging-guided photodynamic-immunotherapy

Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress

(2021) Zhusheng Huang et al.   Nature Communications

Stromal Modulation and Treatment of Metastatic Pancreatic Cancer with Local Intraperitoneal Triple miRNA/siRNA Nanotherapy

(2020) Ying Xie et al.   ACS Nano

A versatile nanoplatform for synergistic chemo-photothermal therapy and multimodal imaging against breast cancer

(2020) Tingting Li et al.   Expert Opinion on Drug Delivery

Nanoparticle interactions with immune cells dominate tumor retention and induce T cell–mediated tumor suppression in models of breast cancer

(2020) Preethi Korangath et al.   Science Advances

Programmable Delivery of Immune Adjuvant to Tumor-Infiltrating Dendritic Cells for Cancer Immunotherapy

(2020) Jing Liu et al.   NANO LETTERS

Reprogramming of tumor-associated macrophages by targeting β-catenin/FOSL2/ARID5A signaling: A potential treatment of lung cancer

(2020) Poonam Sarode et al.   Science Advances

Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death

(2020) Hongzhang Deng et al.   Nature Communications

AIE Multinuclear Ir(III) Complexes for Biocompatible Organic Nanoparticles with Highly Enhanced Photodynamic Performance

(2019) Liping Zhang et al.   Advanced Science

Robust Photodynamic Therapy Using 5-ALA-Incorporated Nanocomplexes Cures Metastatic Melanoma through Priming of CD4+ CD8+ Double Positive T Cells

(2019) Zhi Li et al.   Advanced Science

Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer

(2019) Jun Zhao et al.   Nature Communications

Recent advancements in mesoporous silica nanoparticles towards therapeutic applications for cancer

(2019) Tingting Li et al.   Acta Biomaterialia

Development of immune checkpoint therapy for cancer

(2019) Jill M. Fritz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PI3Kgamma Inhibitor Attenuates Immunosuppressive Effect of Poly( l ‐Glutamic Acid)‐Combretastatin A4 Conjugate in Metastatic Breast Cancer

(2019) Hanjiao Qin et al.   Advanced Science

Biomimetic Nanotherapies: Red Blood Cell Based Core–Shell Structured Nanocomplexes for Atherosclerosis Management

(2019) Yi Wang et al.   Advanced Science

Automated image analysis of NSCLC biopsies to predict response to anti-PD-L1 therapy

(2019) Sonja Althammer et al.   Journal for ImmunoTherapy of Cancer

Ferrimagnetic Vortex Nanoring-Mediated Mild Magnetic Hyperthermia Imparts Potent Immunological Effect for Treating Cancer Metastasis

(2019) Xiaoli Liu et al.   ACS Nano

Highly efficient cascading synergy of cancer photo-immunotherapy enabled by engineered graphene quantum dots/photosensitizer/CpG oligonucleotides hybrid nanotheranostics

(2019) Chunhui Wu et al.   BIOMATERIALS

Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells

(2019) Wen-Long Liu et al.   Nature Communications

Immune Checkpoint Blockade Mediated by a Small‐Molecule Nanoinhibitor Targeting the PD‐1/PD‐L1 Pathway Synergizes with Photodynamic Therapy to Elicit Antitumor Immunity and Antimetastatic Effects on Breast Cancer

(2019) Rui Zhang et al.   Small

Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection

(2019) Francisco Caiado et al.   Nature Communications

Laser Immunotherapy in Combination with Perdurable PD-1 Blocking for Treatment of Metastatic Tumor

(2018) Lihua Luo et al.   ACS Nano

Evolution of checkpoint inhibitors for the treatment of metastatic gastric cancers: Current status and future perspectives

(2018) Julien Taieb et al.   CANCER TREATMENT REVIEWS

Loss of NF-κB1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner

(2018) Lorraine A. O’Reilly et al.   IMMUNITY

Development of small-molecule immune checkpoint inhibitors of PD-1/PD-L1 as a new therapeutic strategy for tumour immunotherapy

(2018) Kui Li et al.   JOURNAL OF DRUG TARGETING

Irinotecan/IR-820 coloaded nanocomposite as a cooperative nanoplatform for combinational therapy of tumor

(2018) Tingting Li et al.   Nanomedicine

An anionic phthalocyanine decreases NRAS expression by breaking down its RNA G-quadruplex

(2018) Keiko Kawauchi et al.   Nature Communications

Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy

(2018) Kaiyuan Ni et al.   Nature Communications

Precision therapeutic targeting of human cancer cell motility

(2018) Li Xu et al.   Nature Communications

M1 Macrophage-Derived Nanovesicles Potentiate the Anticancer Efficacy of Immune Checkpoint Inhibitors

(2018) Yeon Woong Choo et al.   ACS Nano

Hypoxia-Triggered Transforming Immunomodulator for Cancer Immunotherapy via Photodynamically Enhanced Antigen Presentation of Dendritic Cell

(2018) Sooseok Im et al.   ACS Nano

Thermo- and pH-responsive, Lipid-coated, Mesoporous Silica Nanoparticle-based Dual Drug Delivery System To Improve the Antitumor Effect of Hydrophobic Drugs

(2018) Yi Feng et al.   MOLECULAR PHARMACEUTICS

High-Performance Concurrent Chemo-Immuno-Radiotherapy for the Treatment of Hematologic Cancer through Selective High-Affinity Ligand Antibody Mimic-Functionalized Doxorubicin-Encapsulated Nanoparticles

(2018) Kin Man Au et al.   ACS Central Science

Nivolumab and pembrolizumab: Monoclonal antibodies against programmed cell death-1 (PD-1) that are interchangeable

(2017) Vinay Prasad et al.   SEMINARS IN ONCOLOGY

Tumor-selective catalytic nanomedicine by nanocatalyst delivery

(2017) Minfeng Huo et al.   Nature Communications

Folate-Functionalized Magnetic-Mesoporous Silica Nanoparticles for Drug/Gene Codelivery To Potentiate the Antitumor Efficacy

(2016) Tingting Li et al.   ACS Applied Materials & Interfaces

Smart Superstructures with Ultrahigh pH-Sensitivity for Targeting Acidic Tumor Microenvironment: Instantaneous Size Switching and Improved Tumor Penetration

(2016) Hong-Jun Li et al.   ACS Nano

Facilitating T Cell Infiltration in Tumor Microenvironment Overcomes Resistance to PD-L1 Blockade

(2016) Haidong Tang et al.   CANCER CELL

Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4 + T Cell Immunity

(2016) Deshapriya S. Karunarathne et al.   IMMUNITY

Ultralow-Power Near Infrared Lamp Light Operable Targeted Organic Nanoparticle Photodynamic Therapy

(2016) Ling Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Type 1 diabetes vaccine candidates promote human Foxp3+Treg induction in humanized mice

(2016) Isabelle Serr et al.   Nature Communications

Targeting myeloid-derived suppressor cells using a novel adenosine monophosphate-activated protein kinase (AMPK) activator

(2016) Prashant Trikha et al.   OncoImmunology

Polyetherimide-grafted Fe3O4@SiO2 nanoparticles as theranostic agents for simultaneous VEGF siRNA delivery and magnetic resonance cell imaging

(2015) Yiyao Liu et al.   International Journal of Nanomedicine

Immune Checkpoint Blockade in Cancer Therapy

(2015) Michael A. Postow et al.   JOURNAL OF CLINICAL ONCOLOGY

Cutaneous immunology: basics and new concepts

(2015) Amir S. Yazdi et al.   Seminars in Immunopathology

Whole-exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas

(2015) Lauren Fishbein et al.   Nature Communications

Controlled Intracellular Release of Doxorubicin in Multidrug-Resistant Cancer Cells by Tuning the Shell-Pore Sizes of Mesoporous Silica Nanoparticles

(2011) Yu Gao et al.   ACS Nano

Photodynamic therapy of cancer: An update

(2011) Patrizia Agostinis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

BIM Expression in Treatment-Naive Cancers Predicts Responsiveness to Kinase Inhibitors

(2011) A. C. Faber et al.   Cancer Discovery

The disruption of bacterial membrane integrity through ROS generation induced by nanohybrids of silver and clay

(2009) Hong-Lin Su et al.   BIOMATERIALS

Surfactant-free synthesis of mesoporous and hollow silica nanoparticles with an inorganic template

(2009) Luca Baù et al.   CHEMICAL COMMUNICATIONS