Red Blood Cell Cryopreservation with Minimal Post-Thaw Lysis Enabled by a Synergistic Combination of a Cryoprotecting Polyampholyte with DMSO/Trehalose

Cryopreservation of primary cultures of mammalian somatic cells in 96-well plates benefits from control of ice nucleation

(2020) Martin I. Daily et al.   CRYOBIOLOGY

Combinatorial Biomaterials Discovery Strategy to Identify New Macromolecular Cryoprotectants

(2020) Christopher Stubbs et al.   ACS Macro Letters

Post-Thaw Culture and Measurement of Total Cell Recovery Is Crucial in the Evaluation of New Macromolecular Cryoprotectants

(2020) Kathryn A. Murray et al.   BIOMACROMOLECULES

Mimicking the Ice Recrystallization Activity of Biological Antifreezes. When is a New Polymer “Active”?

(2019) Caroline I. Biggs et al.   MACROMOLECULAR BIOSCIENCE

Synthetically Scalable Poly(ampholyte) Which Dramatically Enhances Cellular Cryopreservation

(2019) Trisha L. Bailey et al.   BIOMACROMOLECULES

Polyampholytes as Emerging Macromolecular Cryoprotectants

(2019) Christopher Stubbs et al.   BIOMACROMOLECULES

Extracellular Antifreeze Protein Significantly Enhances the Cryopreservation of Cell Monolayers

(2019) Ruben M. F. Tomás et al.   BIOMACROMOLECULES

Bioinspired Ice Growth Inhibitors Based on Self-Assembling Peptides

(2019) Bin Xue et al.   ACS Macro Letters

Ice Recrystallization Inhibiting Polymers Enable Glycerol-Free Cryopreservation of Microorganisms

(2018) Muhammad Hasan et al.   BIOMACROMOLECULES

Intracellular Delivery of Trehalose for Cell Banking

(2018) Samantha Stewart et al.   LANGMUIR

Synthetic Polyampholytes as Macromolecular Cryoprotective Agents

(2018) Jing Zhao et al.   LANGMUIR

The Use of Frozen and Deglycerolized Red Blood Cells

(2018) Andrew Cap et al.   MILITARY MEDICINE

Exploring the Possibility of Cryopreservation of Feline and Canine Erythrocytes by Rapid Freezing with Penetrating and Non-Penetrating Cryoprotectants

(2017) Denys Pogozhykh et al.   PLoS One

From ice-binding proteins to bio-inspired antifreeze materials

(2017) I. K. Voets   Soft Matter

Polymer mimics of biomacromolecular antifreezes

(2017) Caroline I. Biggs et al.   Nature Communications

Theoretical and experimental study of the antifreeze protein AFP752, trehalose and dimethyl sulfoxide cryoprotection mechanism: correlation with cryopreserved cell viability

(2017) Irena Kratochvílová et al.   RSC Advances

Toxic effects of dimethyl sulfoxide on red blood cells, platelets, and vascular endothelial cells in vitro

(2017) Xiaoyang Yi et al.   FEBS Open Bio

Conjugation Strategy Strongly Impacts the Conformational Stability of a PEG-Protein Conjugate

(2016) Paul B. Lawrence et al.   ACS Chemical Biology

Graphene Oxide Restricts Growth and Recrystallization of Ice Crystals

(2016) Hongya Geng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ice-Binding Proteins and Their Function

(2016) Maya Bar Dolev et al.   Annual Review of Biochemistry

Regioregular Alternating Polyampholytes Have Enhanced Biomimetic Ice Recrystallization Activity Compared to Random Copolymers and the Role of Side Chain versus Main Chain Hydrophobicity

(2016) Christopher Stubbs et al.   BIOMACROMOLECULES

Toward a Molecular Understanding of the Mechanism of Cryopreservation by Polyampholytes: Cell Membrane Interactions and Hydrophobicity

(2016) Robin Rajan et al.   BIOMACROMOLECULES

A study of the osmotic characteristics, water permeability, and cryoprotectant permeability of human vaginal immune cells

(2016) Zhiquan Shu et al.   CRYOBIOLOGY

Small molecule ice recrystallization inhibitors mitigate red blood cell lysis during freezing, transient warming and thawing

(2016) Jennie G. Briard et al.   Scientific Reports

Cryopreservation of a Two-Dimensional Monolayer Using a Slow Vitrification Method with Polyampholyte to Inhibit Ice Crystal Formation

(2016) Kazuaki Matsumura et al.   ACS Biomaterials-Science & Engineering

Cryopreservation of a Two-Dimensional Monolayer Using a Slow Vitrification Method with Polyampholyte to Inhibit Ice Crystal Formation

(2016) Kazuaki Matsumura et al.   ACS Biomaterials Science & Engineering

Comparison of the effects of glycerol, dimethyl sulfoxide, and hydroxyethyl starch solutions for cryopreservation of avian red blood cells

(2015) Jennifer E. Graham et al.   AMERICAN JOURNAL OF VETERINARY RESEARCH

Transfusion of Cryopreserved Packed Red Blood Cells Is Safe and Effective After Trauma

(2015) Martin A. Schreiber et al.   ANNALS OF SURGERY

Cryoprotectant Toxicity: Facts, Issues, and Questions

(2015) Benjamin P. Best   REJUVENATION RESEARCH

Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations

(2015) Chantelle J. Capicciotti et al.   Scientific Reports

Glycerol-Free Cryopreservation of Red Blood Cells Enabled by Ice-Recrystallization-Inhibiting Polymers

(2015) Robert C. Deller et al.   ACS Biomaterials-Science & Engineering

Glycerol-Free Cryopreservation of Red Blood Cells Enabled by Ice-Recrystallization-Inhibiting Polymers

(2015) Robert C. Deller et al.   ACS Biomaterials Science & Engineering

A Comparison of Whole Blood and Plasma Osmolality and Osmolarity

(2014) Samuel N. Cheuvront et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Red blood cell storage lesion

(2014) Rafael Obrador et al.   JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE

Synthetic polymers enable non-vitreous cellular cryopreservation by reducing ice crystal growth during thawing

(2014) Robert C. Deller et al.   Nature Communications

Trehalose Glycopolymers as Excipients for Protein Stabilization

(2013) Juneyoung Lee et al.   BIOMACROMOLECULES

Unexpected low-dose toxicity of the universal solvent DMSO

(2013) Joana Galvao et al.   FASEB JOURNAL

Mechanism of Protein Stabilization by Trehalose During Freeze-Drying Analyzed by In Situ Micro-Raman Spectroscopy

(2013) Alain Hedoux et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Overwintering Strategy and Mechanisms of Cold Tolerance in the Codling Moth (Cydia pomonella)

(2013) Jan Rozsypal et al.   PLoS One

A comprehensive ovine model of blood transfusion

(2013) G. Simonova et al.   VOX SANGUINIS

Trehalose Glycopolymers for Stabilization of Protein Conjugates to Environmental Stressors

(2012) Rock J. Mancini et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Potent inhibition of ice recrystallization by low molecular weight carbohydrate-based surfactants and hydrogelators

(2012) Chantelle J. Capicciotti et al.   Chemical Science

pH-responsive polymers for trehalose loading and desiccation protection of human red blood cells

(2011) Andrew L. Lynch et al.   BIOMATERIALS

Slowing the growth of ice with synthetic macromolecules: beyond antifreeze(glyco) proteins

(2010) Matthew I. Gibson   Polymer Chemistry

Polyampholytes as low toxic efficient cryoprotective agents with antifreeze protein properties

(2009) Kazuaki Matsumura et al.   BIOMATERIALS

ATP-dependent mechanics of red blood cells

(2009) T. Betz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydration IndexA Better Parameter for Explaining Small Molecule Hydration in Inhibition of Ice Recrystallization

(2008) Roger Y. Tam et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Frozen red blood cells: cold comfort in a disaster?

(2008)   TRANSFUSION