The axonal radial contractility: Structural basis underlying a new form of neural plasticity

Unveiling the polarity of actin filaments by cryo-electron tomography

(2021) Bruno Martins et al.   STRUCTURE

Periaxonal and nodal plasticities modulate action potential conduction in the adult mouse brain

(2021) Carlie L. Cullen et al.   Cell Reports

Cytoskeletal organization of axons in vertebrates and invertebrates

(2020) Andreas Prokop   JOURNAL OF CELL BIOLOGY

The axonal actin-spectrin lattice acts as a tension buffering shock absorber

(2020) Sushil Dubey et al.   eLife

The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction

(2020) Ana Rita Costa et al.   eLife

Giant ankyrin-B suppresses stochastic collateral axon branching through direct interaction with microtubules

(2020) Keyu Chen et al.   JOURNAL OF CELL BIOLOGY

Tropomyosin Tpm3.1 Is Required to Maintain the Structure and Function of the Axon Initial Segment

(2020) Amr Abouelezz et al.   iScience

Non-Muscle Myosin II in Axonal Cell Biology: From the Growth Cone to the Axon Initial Segment

(2020) Ana Rita Costa et al.   Cells

Actomyosin Contractility in the Generation and Plasticity of Axons and Dendritic Spines

(2020) Marina Mikhaylova et al.   Cells

Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies

(2020) Rachel S. Gormal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myosin IIB assembly state determines its mechanosensitive dynamics

(2019) Eric S. Schiffhauer et al.   JOURNAL OF CELL BIOLOGY

Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration

(2019) Guiping Wang et al.   eLife

Colocation of Tpm3.1 and myosin IIa heads defines a discrete subdomain in stress fibres

(2019) Joyce C. M. Meiring et al.   JOURNAL OF CELL SCIENCE

ANK2 autism mutation targeting giant ankyrin-B promotes axon branching and ectopic connectivity

(2019) Rui Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sub-membranous actin rings in the axon initial segment are resistant to the action of latrunculin

(2019) Amr Abouelezz et al.   BIOLOGICAL CHEMISTRY

The Roles of Microtubules and Membrane Tension in Axonal Beading, Retraction, and Atrophy

(2019) Anagha Datar et al.   BIOPHYSICAL JOURNAL

Membrane-associated periodic skeleton is a signaling platform for RTK transactivation in neurons

(2019) Ruobo Zhou et al.   SCIENCE

The model of local axon homeostasis - explaining the role and regulation of microtubule bundles in axon maintenance and pathology

(2019) Ines Hahn et al.   Neural Development

Axonal transport: Driving synaptic function

(2019) Pedro Guedes-Dias et al.   SCIENCE

Super-resolution imaging of fluorescent dipoles via polarized structured illumination microscopy

(2019) Karl Zhanghao et al.   Nature Communications

Tau interactome analyses in CRISPR-Cas9 engineered neuronal cells reveal ATPase-dependent binding of wild-type but not P301L Tau to non-muscle myosins

(2019) Xinzhu Wang et al.   Scientific Reports

Ultrastructure of the axonal periodic scaffold reveals a braid-like organization of actin rings

(2019) Stéphane Vassilopoulos et al.   Nature Communications

Actin Assemblies in the Axon Shaft – some Open Questions

(2018) Pankaj Dubey et al.   CURRENT OPINION IN NEUROBIOLOGY

The actin cortex at a glance

(2018) Priyamvada Chugh et al.   JOURNAL OF CELL SCIENCE

The Axon Initial Segment: An Updated Viewpoint

(2018) Christophe Leterrier   JOURNAL OF NEUROSCIENCE

Localized Myosin II Activity Regulates Assembly and Plasticity of the Axon Initial Segment

(2018) Stephen L. Berger et al.   NEURON

Myosin IIA interacts with the spectrin-actin membrane skeleton to control red blood cell membrane curvature and deformability

(2018) Alyson S. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Remodeling of the Actin/Spectrin Membrane-associated Periodic Skeleton, Growth Cone Collapse and F-Actin Decrease during Axonal Degeneration

(2018) Nicolas Unsain et al.   Scientific Reports

The Spectrin-Actin-Based Periodic Cytoskeleton as a Conserved Nanoscale Scaffold and Ruler of the Neural Stem Cell Lineage

(2018) Meghan Hauser et al.   Cell Reports

Morphology of mitochondria in spatially restricted axons revealed by cryo-electron tomography

(2018) Tara D. Fischer et al.   PLOS BIOLOGY

Processive flow by biased polymerization mediates the slow axonal transport of actin

(2018) Nilaj Chakrabarty et al.   JOURNAL OF CELL BIOLOGY

Myosin II activity is required for structural plasticity at the axon initial segment

(2017) Mark D. Evans et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Polarity of varicosity initiation in central neuron mechanosensation

(2017) Yuanzheng Gu et al.   JOURNAL OF CELL BIOLOGY

Periodic actin structures in neuronal axons are required to maintain microtubules

(2017) Yue Qu et al.   MOLECULAR BIOLOGY OF THE CELL

Actin dynamics and competition for myosin monomer govern the sequential amplification of myosin filaments

(2017) Jordan R. Beach et al.   NATURE CELL BIOLOGY

Structural organization of the actin-spectrin–based membrane skeleton in dendrites and soma of neurons

(2017) Boran Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Superresolution imaging reveals activity-dependent plasticity of axon morphology linked to changes in action potential conduction velocity

(2017) Ronan Chéreau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drosophila Short stop as a paradigm for the role and regulation of spectraplakins

(2017) André Voelzmann et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mechanical Properties of the Cytoskeleton and Cells

(2017) Adrian F. Pegoraro et al.   Cold Spring Harbor Perspectives in Biology

Axon tension regulates fasciculation/defasciculation through the control of axon shaft zippering

(2017) Daniel Šmít et al.   eLife

Genetic defects in β-spectrin and tau sensitize C. elegans axons to movement-induced damage via torque-tension coupling

(2017) Michael Krieg et al.   eLife

Coupled circumferential and axial tension driven by actin and myosin influences in vivo axon diameter

(2017) Anthony Fan et al.   Scientific Reports

Role of tau in the spatial organization of axonal microtubules: keeping parallel microtubules evenly distributed despite macromolecular crowding

(2016) Alix Méphon-Gaspard et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The neuronal and actin commitment: Why do neurons need rings?

(2016) Sérgio Carvalho Leite et al.   Cytoskeleton

A close look at axonal transport: Cargos slow down when crossing stationary organelles

(2016) Daphne L. Che et al.   NEUROSCIENCE LETTERS

Prevalent presence of periodic actin–spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species

(2016) Jiang He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB

(2016) Tong Wang et al.   Nature Communications

The Actin-Binding Protein α-Adducin Is Required for Maintaining Axon Diameter

(2016) Sérgio Carvalho Leite et al.   Cell Reports

Coordinating Neuronal Actin–Microtubule Dynamics

(2015) Charlotte H. Coles et al.   CURRENT BIOLOGY

L1CAM/Neuroglian controls the axon–axon interactions establishing layered and lobular mushroom body architecture

(2015) Dominique Siegenthaler et al.   JOURNAL OF CELL BIOLOGY

A dynamic formin-dependent deep F-actin network in axons

(2015) Archan Ganguly et al.   JOURNAL OF CELL BIOLOGY

Structural Components of Synaptic Plasticity and Memory Consolidation

(2015) Craig H. Bailey et al.   Cold Spring Harbor Perspectives in Biology

Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle docking

(2015) Andreas Papadopulos et al.   Nature Communications

Tau co-organizes dynamic microtubule and actin networks

(2015) Auréliane Elie et al.   Scientific Reports

Nanoscale Architecture of the Axon Initial Segment Reveals an Organized and Robust Scaffold

(2015) Christophe Leterrier et al.   Cell Reports

STED Nanoscopy Reveals the Ubiquity of Subcortical Cytoskeleton Periodicity in Living Neurons

(2015) Elisa D’Este et al.   Cell Reports

The Physiological Molecular Shape of Spectrin: A Compact Supercoil Resembling a Chinese Finger Trap

(2015) Jeffrey W. Brown et al.   PLoS Computational Biology

Distribution of axon diameters in cortical white matter: an electron-microscopic study on three human brains and a macaque

(2014) Daniel Liewald et al.   BIOLOGICAL CYBERNETICS

Axonal Transport: How High Microtubule Density Can Compensate for Boundary Effects in Small-Caliber Axons

(2014) Juliana C. Wortman et al.   BIOPHYSICAL JOURNAL

In vivo correlation between axon diameter and conduction velocity in the human brain

(2014) Assaf Horowitz et al.   Brain Structure & Function

Spectraplakins

(2014) Sven Huelsmann et al.   CURRENT BIOLOGY

Nonmuscle Myosin II Isoforms Coassemble in Living Cells

(2014) Jordan R. Beach et al.   CURRENT BIOLOGY

Endogenous Species of Mammalian Nonmuscle Myosin IIA and IIB Include Activated Monomers and Heteropolymers

(2014) Maria S. Shutova et al.   CURRENT BIOLOGY

A Biophysical Analysis of Mitochondrial Movement: Differences Between Transport in Neuronal Cell Bodies Versus Processes

(2014) Babu Reddy Janakaloti Narayanareddy et al.   TRAFFIC

De Novo Mutations in Moderate or Severe Intellectual Disability

(2014) Fadi F. Hamdan et al.   PLoS Genetics

Developmental mechanism of the periodic membrane skeleton in axons

(2014) Guisheng Zhong et al.   eLife

Cannabinoid-induced actomyosin contractility shapes neuronal morphology and growth

(2014) Alexandre B Roland et al.   eLife

The structural dynamics of α-tropomyosin on F-actin shape the overlap complex between adjacent tropomyosin molecules

(2013) William Lehman et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

(2012) Sandra Maday et al.   JOURNAL OF CELL BIOLOGY

Spectraplakins: Master orchestrators of cytoskeletal dynamics

(2012) Kathleen C. Suozzi et al.   JOURNAL OF CELL BIOLOGY

Neurofilaments at a glance

(2012) A. Yuan et al.   JOURNAL OF CELL SCIENCE

Spectraplakins Promote Microtubule-Mediated Axonal Growth by Functioning As Structural Microtubule-Associated Proteins and EB1-Dependent +TIPs (Tip Interacting Proteins)

(2012) J. Alves-Silva et al.   JOURNAL OF NEUROSCIENCE

Why Do Axons Differ in Caliber?

(2012) J. A. Perge et al.   JOURNAL OF NEUROSCIENCE

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

(2012) Brian J. O’Roak et al.   NATURE

Functions of Nonmuscle Myosin II in Assembly of the Cellular Contractile System

(2012) Maria Shutova et al.   PLoS One

Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis

(2012) X. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons

(2012) K. Xu et al.   SCIENCE

Synapses and Memory Storage

(2012) M. Mayford et al.   Cold Spring Harbor Perspectives in Biology

Synaptic Functions of Invertebrate Varicosities: What Molecular Mechanisms Lie Beneath

(2012) Carlo Natale Giuseppe Giachello et al.   NEURAL PLASTICITY

Phosphorylation of the myosin IIA tailpiece regulates single myosin IIA molecule association with lytic granules to promote NK-cell cytotoxicity

(2011) K. B. Sanborn et al.   BLOOD

A Molecular Pathway for Myosin II Recruitment to Stress Fibers

(2011) Sari Tojkander et al.   CURRENT BIOLOGY

Regional changes in type 1 cannabinoid receptor availability in Parkinson's disease in vivo

(2011) Koen Van Laere et al.   NEUROBIOLOGY OF AGING

Drosophila Neurons Actively Regulate Axonal Tension In Vivo

(2010) Jagannathan Rajagopalan et al.   BIOPHYSICAL JOURNAL

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

Synaptic organizing complexes

(2010) Tabrez J Siddiqui et al.   CURRENT OPINION IN NEUROBIOLOGY

The Spectraplakin Short Stop Is an Actin–Microtubule Cross-Linker That Contributes to Organization of the Microtubule Network

(2010) Derek A. Applewhite et al.   MOLECULAR BIOLOGY OF THE CELL

Conditional Ablation of Nonmuscle Myosin II-B Delineates Heart Defects in Adult Mice

(2009) Xuefei Ma et al.   CIRCULATION RESEARCH

Quantitative analysis of multivesicular bodies (MVBs) in the hypoglossal nerve: Evidence that neurotrophic factors do not use MVBs for retrograde axonal transport

(2009) Amy L. Altick et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The Shape and Flexibility of Tropomyosin Coiled Coils: Implications for Actin Filament Assembly and Regulation

(2009) Xiaochuan (Edward) Li et al.   JOURNAL OF MOLECULAR BIOLOGY

Signal transduction of the CB1 cannabinoid receptor

(2009) Gábor Turu et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Neurofilaments Bind Tubulin and Modulate Its Polymerization

(2009) A. Bocquet et al.   JOURNAL OF NEUROSCIENCE

How the Optic Nerve Allocates Space, Energy Capacity, and Information

(2009) J. A. Perge et al.   JOURNAL OF NEUROSCIENCE

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanical tension contributes to clustering of neurotransmitter vesicles at presynaptic terminals

(2009) S. Siechen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Trade-Offs in White Matter Axonal Scaling

(2008) S. S.-H. Wang et al.   JOURNAL OF NEUROSCIENCE

Multiple Regulatory Steps Control Mammalian Nonmuscle Myosin II Assembly in Live Cells

(2008) Mark T. Breckenridge et al.   MOLECULAR BIOLOGY OF THE CELL

Review of the Multiple Aspects of Neurofilament Functions, and their Possible Contribution to Neurodegeneration

(2008) Rodolphe Perrot et al.   MOLECULAR NEUROBIOLOGY