Cytoskeletal organization of axons in vertebrates and invertebrates

A Combinatorial MAP Code Dictates Polarized Microtubule Transport

(2020) Brigette Y. Monroy et al.   DEVELOPMENTAL CELL

Activity-Dependent Plasticity of Axo-axonic Synapses at the Axon Initial Segment

(2020) Alejandro Pan-Vazquez et al.   NEURON

Multiple Domains in the Kv7.3 C-Terminus Can Regulate Localization to the Axon Initial Segment

(2020) Louise Leth Hefting et al.   Frontiers in Cellular Neuroscience

Mapping axon initial segment structure and function by multiplexed proximity biotinylation

(2020) Hamdan Hamdan et al.   Nature Communications

Nodal β spectrins are required to maintain Na+ channel clustering and axon integrity

(2020) Cheng-Hsin Liu et al.   eLife

Three‐dimensional organization of the cytoskeleton: A cryo‐electron tomography perspective

(2020) Saikat Chakraborty et al.   PROTEIN SCIENCE

The axonal actin-spectrin lattice acts as a tension buffering shock absorber

(2020) Sushil Dubey et al.   eLife

Cortical anchoring of the microtubule cytoskeleton is essential for neuron polarity

(2020) Liu He et al.   eLife

The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction

(2020) Ana Rita Costa et al.   eLife

Location and Plasticity of the Sodium Spike Initiation Zone in Nociceptive Terminals In Vivo

(2019) Robert H. Goldstein et al.   NEURON

TRIM46 organizes microtubule fasciculation in the axon initial segment

(2019) Martin Harterink et al.   JOURNAL OF NEUROSCIENCE

ANK2 autism mutation targeting giant ankyrin-B promotes axon branching and ectopic connectivity

(2019) Rui Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic Regulation of Synaptopodin and the Axon Initial Segment in Retinal Ganglion Cells During Postnatal Development

(2019) Annabelle Schlüter et al.   Frontiers in Cellular Neuroscience

Feedback-Driven Assembly of the Axon Initial Segment

(2019) Amélie Fréal et al.   NEURON

Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis

(2019) Peter Dongmin Sohn et al.   NEURON

An unfolding role for ankyrin-G at the axon initial segment

(2019) James L. Salzer   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The model of local axon homeostasis - explaining the role and regulation of microtubule bundles in axon maintenance and pathology

(2019) Ines Hahn et al.   Neural Development

Microtubule-Associated Proteins: Structuring the Cytoskeleton

(2019) Satish Bodakuntla et al.   TRENDS IN CELL BIOLOGY

Mechanistic insights into the interactions of dynein regulator Ndel1 with neuronal ankyrins and implications in polarity maintenance

(2019) Jin Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrastructure of the axonal periodic scaffold reveals a braid-like organization of actin rings

(2019) Stéphane Vassilopoulos et al.   Nature Communications

Axon initial segments: structure, function, and disease

(2018) Claire Yu-Mei Huang et al.   Annals of the New York Academy of Sciences

The Axon Initial Segment: An Updated Viewpoint

(2018) Christophe Leterrier   JOURNAL OF NEUROSCIENCE

Genome survey sequencing of red swamp crayfish Procambarus clarkii

(2018) Linlin Shi et al.   MOLECULAR BIOLOGY REPORTS

Localized Myosin II Activity Regulates Assembly and Plasticity of the Axon Initial Segment

(2018) Stephen L. Berger et al.   NEURON

Rbfox Splicing Factors Promote Neuronal Maturation and Axon Initial Segment Assembly

(2018) Martin Jacko et al.   NEURON

Intermediate filament accumulation can stabilize microtubules inCaenorhabditis elegansmotor neurons

(2018) Naina Kurup et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The intriguing nature of dorsal root ganglion neurons: linking structure with polarity and function

(2018) Ana Isabel Nascimento et al.   PROGRESS IN NEUROBIOLOGY

Competition between microtubule-associated proteins directs motor transport

(2018) Brigette Y. Monroy et al.   Nature Communications

The HAUS Complex Is a Key Regulator of Non-centrosomal Microtubule Organization during Neuronal Development

(2018) Inês Cunha-Ferreira et al.   Cell Reports

The Regulation of Axon Diameter: From Axonal Circumferential Contractility to Activity-Dependent Axon Swelling

(2018) Ana Rita Costa et al.   Frontiers in Molecular Neuroscience

Large Volume Electron Microscopy and Neural Microcircuit Analysis

(2018) Yoshiyuki Kubota et al.   Frontiers in Neural Circuits

Myosin II activity is required for structural plasticity at the axon initial segment

(2017) Mark D. Evans et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Periodic actin structures in neuronal axons are required to maintain microtubules

(2017) Yue Qu et al.   MOLECULAR BIOLOGY OF THE CELL

The nano-architecture of the axonal cytoskeleton

(2017) Christophe Leterrier et al.   NATURE REVIEWS NEUROSCIENCE

Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions

(2017) Mei-Yao Lin et al.   NEURON

MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus KIF5-Dependent Cargo Transport in Sensory Neurons

(2017) Laura F. Gumy et al.   NEURON

Differentiation between Oppositely Oriented Microtubules Controls Polarized Neuronal Transport

(2017) Roderick P. Tas et al.   NEURON

Drosophila Short stop as a paradigm for the role and regulation of spectraplakins

(2017) André Voelzmann et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Ankyrin G Membrane Partners Drive the Establishment and Maintenance of the Axon Initial Segment

(2017) Christophe Leterrier et al.   Frontiers in Cellular Neuroscience

Structure and Function of an Actin-Based Filter in the Proximal Axon

(2017) Varuzhan Balasanyan et al.   Cell Reports

Enhanced FIB-SEM systems for large-volume 3D imaging

(2017) C Shan Xu et al.   eLife

Genetic defects in β-spectrin and tau sensitize C. elegans axons to movement-induced damage via torque-tension coupling

(2017) Michael Krieg et al.   eLife

Role of tau in the spatial organization of axonal microtubules: keeping parallel microtubules evenly distributed despite macromolecular crowding

(2016) Alix Méphon-Gaspard et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Arthropod neurons and nervous system

(2016) Carmen Ramona Smarandache-Wellmann   CURRENT BIOLOGY

Stability properties of neuronal microtubules

(2016) Peter W. Baas et al.   Cytoskeleton

Nanoscopic compartmentalization of membrane protein motion at the axon initial segment

(2016) David Albrecht et al.   JOURNAL OF CELL BIOLOGY

Dendrites In Vitro and In Vivo Contain Microtubules of Opposite Polarity and Axon Formation Correlates with Uniform Plus-End-Out Microtubule Orientation

(2016) K. W. Yau et al.   JOURNAL OF NEUROSCIENCE

Dynein Regulator NDEL1 Controls Polarized Cargo Transport at the Axon Initial Segment

(2016) Marijn Kuijpers et al.   NEURON

Microtubule Organization Determines Axonal Transport Dynamics

(2016) Shaul Yogev et al.   NEURON

Intermediate Filaments: Structure and Assembly

(2016) Harald Herrmann et al.   Cold Spring Harbor Perspectives in Biology

Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity

(2016) Carlos Sánchez-Huertas et al.   Nature Communications

Axon Initial Segment Cytoskeleton: Architecture, Development, and Role in Neuron Polarity

(2016) Steven L. Jones et al.   NEURAL PLASTICITY

Dynamic Microtubules Drive Circuit Rewiring in the Absence of Neurite Remodeling

(2015) Naina Kurup et al.   CURRENT BIOLOGY

Evolutionary aspects in intermediate filament proteins

(2015) Annette Peter et al.   CURRENT OPINION IN CELL BIOLOGY

Hierarchical Microtubule Organization Controls Axon Caliber and Transport and Determines Synaptic Structure and Stability

(2015) Raiko Stephan et al.   DEVELOPMENTAL CELL

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays

(2015) Sam F.B. van Beuningen et al.   NEURON

Composite bottlebrush mechanics: α-internexin fine-tunes neurofilament network properties

(2015) M. Kornreich et al.   Soft Matter

Resolving bundled microtubules using anti-tubulin nanobodies

(2015) Marina Mikhaylova et al.   Nature Communications

Redistribution of Kv1 and Kv7 enhances neuronal excitability during structural axon initial segment plasticity

(2015) Hiroshi Kuba et al.   Nature Communications

Rapid Modulation of Axon Initial Segment Length Influences Repetitive Spike Firing

(2015) Mark D. Evans et al.   Cell Reports

Nanoscale Architecture of the Axon Initial Segment Reveals an Organized and Robust Scaffold

(2015) Christophe Leterrier et al.   Cell Reports

Sorting of Dendritic and Axonal Vesicles at the Pre-axonal Exclusion Zone

(2015) Ginny G. Farías et al.   Cell Reports

Distal Spike Initiation Zone Location Estimation by Morphological Simulation of Ionic Current Filtering Demonstrated in a Novel Model of an Identified Drosophila Motoneuron

(2015) Cengiz Günay et al.   PLoS Computational Biology

A Stochastic Multiscale Model That Explains the Segregation of Axonal Microtubules and Neurofilaments in Neurological Diseases

(2015) Chuan Xue et al.   PLoS Computational Biology

Preferential Targeting of Nav1.6 Voltage-Gated Na+ Channels to the Axon Initial Segment during Development

(2015) Elizabeth J. Akin et al.   PLoS One

Giant ankyrin-G: A critical innovation in vertebrate evolution of fast and integrated neuronal signaling

(2015) Paul M. Jenkins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Axonal Transport: How High Microtubule Density Can Compensate for Boundary Effects in Small-Caliber Axons

(2014) Juliana C. Wortman et al.   BIOPHYSICAL JOURNAL

The MAP1B case: An old MAP that is new again

(2014) David Villarroel-Campos et al.   Developmental Neurobiology

Axon initial segment cytoskeleton comprises a multiprotein submembranous coat containing sparse actin filaments

(2014) Steven L. Jones et al.   JOURNAL OF CELL BIOLOGY

Activity-Dependent and Activity-Independent Development of the Axon Initial Segment

(2014) H. Kuba et al.   JOURNAL OF NEUROSCIENCE

Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons

(2014) Dennis Janning et al.   MOLECULAR BIOLOGY OF THE CELL

Spectrins: A structural platform for stabilization and activation of membrane channels, receptors and transporters

(2013) Beata Machnicka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Transglutaminase and Polyamination of Tubulin: Posttranslational Modification for Stabilizing Axonal Microtubules

(2013) Yuyu Song et al.   NEURON

The axonal endoplasmic reticulum and protein trafficking: Cellular bootlegging south of the soma

(2013) Carolina González et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

MAP6-F Is a Temperature Sensor That Directly Binds to and Protects Microtubules from Cold-induced Depolymerization

(2012) Christian Delphin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spectraplakins Promote Microtubule-Mediated Axonal Growth by Functioning As Structural Microtubule-Associated Proteins and EB1-Dependent +TIPs (Tip Interacting Proteins)

(2012) J. Alves-Silva et al.   JOURNAL OF NEUROSCIENCE

Why Do Axons Differ in Caliber?

(2012) J. A. Perge et al.   JOURNAL OF NEUROSCIENCE

Peripherin Is a Subunit of Peripheral Nerve Neurofilaments: Implications for Differential Vulnerability of CNS and Peripheral Nervous System Axons

(2012) A. Yuan et al.   JOURNAL OF NEUROSCIENCE

Signal Processing in the Axon Initial Segment

(2012) Maarten H.P. Kole et al.   NEURON

Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons

(2012) K. Xu et al.   SCIENCE

Networks of Polarized Actin Filaments in the Axon Initial Segment Provide a Mechanism for Sorting Axonal and Dendritic Proteins

(2012) Kaori Watanabe et al.   Cell Reports

Differential Trafficking of Transport Vesicles Contributes to the Localization of Dendritic Proteins

(2012) Sarmad Al-Bassam et al.   Cell Reports

The Cell Adhesion Molecule Neurofascin Stabilizes Axo-axonic GABAergic Terminals at the Axon Initial Segment

(2011) Martin Kriebel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuronal polarity in Drosophila: Sorting out axons and dendrites

(2010) Melissa M. Rolls   Developmental Neurobiology

Hooks and comets: The story of microtubule polarity orientation in the neuron

(2010) Peter W. Baas et al.   Developmental Neurobiology

Conformational Dynamics of Neurofilament Side-Arms

(2010) Mark J. Stevens et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability

(2010) Matthew S. Grubb et al.   NATURE

Presynaptic activity regulates Na+ channel distribution at the axon initial segment

(2010) Hiroshi Kuba et al.   NATURE

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease

(2010) Nobutaka Hirokawa et al.   NEURON

Axon Extension Occurs Independently of Centrosomal Microtubule Nucleation

(2010) M. Stiess et al.   SCIENCE

A novel recessiveNeflmutation causes a severe, early-onset axonal neuropathy

(2009) Sabrina W. Yum et al.   ANNALS OF NEUROLOGY

Mouse ACF7 and Drosophila Short stop modulate filopodia formation and microtubule organisation during neuronal growth

(2009) N. Sanchez-Soriano et al.   JOURNAL OF CELL SCIENCE

Neurofilaments Bind Tubulin and Modulate Its Polymerization

(2009) A. Bocquet et al.   JOURNAL OF NEUROSCIENCE

How the Optic Nerve Allocates Space, Energy Capacity, and Information

(2009) J. A. Perge et al.   JOURNAL OF NEUROSCIENCE

Myosin-dependent targeting of transmembrane proteins to neuronal dendrites

(2009) Tommy L Lewis et al.   NATURE NEUROSCIENCE

AnkyrinG is required to maintain axo-dendritic polarity in vivo

(2009) J.-M. Sobotzik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stretch growth of integrated axon tracts: Extremes and exploitations

(2009) Douglas H. Smith   PROGRESS IN NEUROBIOLOGY

Post-transcriptional control of neurofilaments: New roles in development, regeneration and neurodegenerative disease

(2009) Ben G. Szaro et al.   TRENDS IN NEUROSCIENCES

Docking of Axonal Mitochondria by Syntaphilin Controls Their Mobility and Affects Short-Term Facilitation

(2008) Jian-Sheng Kang et al.   CELL

AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity

(2008) Kristian L. Hedstrom et al.   JOURNAL OF CELL BIOLOGY

Review of the Multiple Aspects of Neurofilament Functions, and their Possible Contribution to Neurodegeneration

(2008) Rodolphe Perrot et al.   MOLECULAR NEUROBIOLOGY

Sodium channel cluster, βIV-spectrin and ankyrinG positive “hot spots” on dendritic segments of parvalbumin-containing neurons and some other neurons in the mouse and rat main olfactory bulbs

(2008) Toshio Kosaka et al.   NEUROSCIENCE RESEARCH

Complementary dimerization of microtubule-associated tau protein: Implications for microtubule bundling and tau-mediated pathogenesis

(2008) K. J. Rosenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA