Targeting NF-κB–dependent alkaliptosis for the treatment of venetoclax-resistant acute myeloid leukemia cells

Mechanisms for resistance in AML insights into molecular pathways mediating resistance to venetoclax

(2021) Marina Y. Konopleva   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Broadening horizons: the role of ferroptosis in cancer

(2021) Xin Chen et al.   Nature Reviews Clinical Oncology

Venetoclax combination therapy in relapsed/refractory acute myeloid leukemia: A single institution experience

(2020) Daria Gaut et al.   LEUKEMIA RESEARCH

Targeting apoptosis in cancer therapy

(2020) Benedito A. Carneiro et al.   Nature Reviews Clinical Oncology

Enhancing venetoclax activity in hematological malignancies

(2020) Toshihisa Satta et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia

(2020) Courtney D. DiNardo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Venetoclax and alvocidib are both cytotoxic to acute myeloid leukemia cells resistant to cytarabine and clofarabine

(2020) Rie Nishi et al.   BMC CANCER

Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins

(2019) Rumani Singh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The molecular machinery of regulated cell death

(2019) Daolin Tang et al.   CELL RESEARCH

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice

(2018) Xinxin Song et al.   GASTROENTEROLOGY

JTC-801 exerts anti-proliferative effects in human osteosarcoma cells by inducing apoptosis

(2018) Chang-Jun Zheng et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

NF-kappaB: Two Sides of the Same Coin

(2018) Bruno Pires et al.   Genes

Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma

(2017) Yangchun Xie et al.   GASTROENTEROLOGY

Acute myeloid leukaemia

(2016) Asim Khwaja et al.   Nature Reviews Disease Primers

HMGB1 in health and disease

(2014) Rui Kang et al.   MOLECULAR ASPECTS OF MEDICINE

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

(2013) Andrew J Souers et al.   NATURE MEDICINE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

NF-κB activation enhances cell death by antimitotic drugs in human prostate cancer cells

(2010) Ricardo Parrondo et al.   Molecular Cancer