UPRmt activation protects against MPP+-induced toxicity in a cell culture model of Parkinson's disease

Multi-OMICS study of a CHCHD10 variant causing ALS demonstrates metabolic rewiring and activation of endoplasmic reticulum and mitochondrial unfolded protein responses

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Activation of Mitochondrial Unfolded Protein Response in SHSY5Y Expressing APP Cells and APP/PS1 Mice

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Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity

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TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response

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Sex specific activation of the ERα axis of the mitochondrial UPR (UPRmt) in the G93A-SOD1 mouse model of familial ALS

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Dysregulation of the Mitochondrial Unfolded Protein Response Induces Non-Apoptotic Dopaminergic Neurodegeneration inC. elegansModels of Parkinson's Disease

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Activation of the mitochondrial unfolded protein response promotes longevity and dopamine neuron survival in Parkinson’s disease models

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Evidence for Mitochondrial UPR Gene Activation in Familial and Sporadic Alzheimer's Disease

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The Transcription Factor ATF5 Mediates a Mammalian Mitochondrial UPR

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Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response

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Mitochondrial and Nuclear Accumulation of the Transcription Factor ATFS-1 Promotes OXPHOS Recovery during the UPRmt

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The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease

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Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease

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Mitochondrial Proteostasis in the Control of Aging and Longevity

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Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection

(2014) Mark W. Pellegrino et al.   NATURE

Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabditis elegans

(2014) Christopher F. Bennett et al.   Nature Communications

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Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation

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Mitochondrial Respiratory Complex I: Structure, Function and Implication in Human Diseases

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