Featured Article: Modulation of fetal hemoglobin in hereditary persistence of fetal hemoglobin deletion type-2, compared to Sicilian δβ-thalassemia, by BCL11A and SOX6-targeting microRNAs

Regulation of the fetal hemoglobin silencing factor BCL11A

(2016) Anindita Basak et al.   Annals of the New York Academy of Sciences

An overview of molecular basis of iron metabolism regulation and the associated pathologies

(2015) Bruno Silva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

HIF-mediated increased ROS from reduced mitophagy and decreased catalase causes neocytolysis

(2015) Jihyun Song et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Fluid Shear Stress Upregulates E-Tmod41 via miR-23b-3p and Contributes to F-Actin Cytoskeleton Remodeling during Erythropoiesis

(2015) Weiyun Mu et al.   PLoS One

The Regulatory Roles of MicroRNA-146b-5p and Its Target Platelet-derived Growth Factor Receptor α (PDGFRA) in Erythropoiesis and Megakaryocytopoiesis

(2014) Peng-Fei Zhai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decreased miR-146 expression in peripheral blood mononuclear cells is correlated with ongoing islet autoimmunity in type 1 diabetes patients 1型糖尿病患者外周血单个核细胞miR-146表达下调与胰岛持续免疫失衡相关

(2014) Minglan Yang et al.   Journal of Diabetes

MicroRNA-486-3p Regulates γ-Globin Expression in Human Erythroid Cells by Directly Modulating BCL11A

(2013) Valentina Lulli et al.   PLoS One

The Switch from Fetal to Adult Hemoglobin

(2013) V. G. Sankaran et al.   Cold Spring Harbor Perspectives in Medicine

Expression profiling of ETO2-regulated miRNAs in erythroid cells: Possible influence on miRNA abundance

(2013) Tohru Fujiwara et al.   FEBS Open Bio

Reawakening fetal hemoglobin: prospects for new therapies for the  -globin disorders

(2012) D. E. Bauer et al.   BLOOD

MicroRNAs as components of regulatory networks controlling erythropoiesis

(2012) Imane Azzouzi et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

A Functional Element Necessary for Fetal Hemoglobin Silencing

(2011) Vijay G. Sankaran et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transcriptional silencing of  -globin by BCL11A involves long-range interactions and cooperation with SOX6

(2010) J. Xu et al.   GENES & DEVELOPMENT

Mechanism of human Hb switching: a possible role of the kit receptor/miR 221-222 complex

(2010) M. Gabbianelli et al.   HAEMATOLOGICA

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites

(2010) Doron Betel et al.   GENOME BIOLOGY

A Brief Review on the Mechanisms of miRNA Regulation

(2010) Yimei Cai et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Developmental and species-divergent globin switching are driven by BCL11A

(2009) Vijay G. Sankaran et al.   NATURE

Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of  -thalassemia

(2008) M. Uda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA polymorphisms at the BCL11A, HBS1L-MYB, and  -globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

(2008) G. Lettre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific RepressorBCL11A

(2008) Vijay G. Sankaran et al.   SCIENCE