Imaging of Cancer Cells and Dictated Cytotoxicity Using Aptamer‐Guided Hybridization Chain Reaction (HCR)‐Generated G‐Quadruplex Chains

Near-infrared Light-Initiated Hybridization Chain Reaction for Spatially- and Temporally-Resolved Signal Amplification

(2019) Hongqian Chu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Single-handed supramolecular double helix of homochiral bis(N-amidothiourea) supported by double crossed C−I···S halogen bonds

(2019) Xiaosheng Yan et al.   Nature Communications

Localized Fe(II)-Induced Cytotoxic Reactive Oxygen Species Generating Nanosystem for Enhanced Anticancer Therapy

(2018) Yuxue Ding et al.   ACS Applied Materials & Interfaces

Construction of an autonomously concatenated hybridization chain reaction for signal amplification and intracellular imaging

(2018) Jie Wei et al.   Chemical Science

Enhancing the Efficacy of Photodynamic Therapy through a Porphyrin/POSS Alternating Copolymer

(2018) Jianqiu Jin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer

(2017) Fangfei Li et al.   Nature Communications

Live Cell MicroRNA Imaging Using Exonuclease III-Aided Recycling Amplification Based on Aggregation-Induced Emission Luminogens

(2016) Xuehong Min et al.   ACS Applied Materials & Interfaces

Combining Two-Photon-Activated Fluorescence Resonance Energy Transfer and Near-Infrared Photothermal Effect of Unimolecular Micelles for Enhanced Photodynamic Therapy

(2016) Yu Huang et al.   ACS Nano

Singlet Oxygen Generation by Laser Irradiation of Gold Nanoparticles

(2016) Samantha J. Chadwick et al.   Journal of Physical Chemistry C

Fluorescence resonance energy transfer-based hybridization chain reaction for in situ visualization of tumor-related mRNA

(2016) Jin Huang et al.   Chemical Science

The diagnostic accuracy of carcinoembryonic antigen to detect colorectal cancer recurrence – A systematic review

(2016) Caspar G. Sørensen et al.   International Journal of Surgery

G-quadruplex/protoporphyrin IX-functionalized silver nanoconjugates for targeted cancer cell photodynamic therapy

(2016) Jun Ai et al.   RSC Advances

TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood

(2016) I. Marginedas-Freixa et al.   Scientific Reports

Catalytic Molecular Imaging of MicroRNA in Living Cells by DNA-Programmed Nanoparticle Disassembly

(2015) Xuewen He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hyperbranched Hybridization Chain Reaction for Triggered Signal Amplification and Concatenated Logic Circuits

(2015) Sai Bi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting the folate receptor: diagnostic and therapeutic approaches to personalize cancer treatments

(2015) J. A. Ledermann et al.   ANNALS OF ONCOLOGY

The Effect of Coatings on the Affinity of Lanthanide Nanoparticles to MKN45 and HeLa Cancer Cells and Improvement in Photodynamic Therapy Efficiency

(2015) Takashi Sawamura et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Live Cell MicroRNA Imaging Using Cascade Hybridization Reaction

(2015) Zoya Cheglakov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

AS1411-conjugated gold nanospheres and their potential for breast cancer therapy

(2015) Mohammad T. Malik et al.   Oncotarget

Next-Generation in Situ Hybridization Chain Reaction: Higher Gain, Lower Cost, Greater Durability

(2014) Harry M. T. Choi et al.   ACS Nano

Nucleolin-targeting liposomes guided by aptamer AS1411 for the delivery of siRNA for the treatment of malignant melanomas

(2014) Liyu Li et al.   BIOMATERIALS

Cell-surface nucleolin acts as a central mediator for carcinogenic, anti-carcinogenic, and disease-related ligands

(2014) Hirota Fujiki et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Aptamer-Targeted DNA Nanostructures for Therapeutic Delivery

(2014) Phapanin Charoenphol et al.   MOLECULAR PHARMACEUTICS

Improved in Vitro Efficacy of Gold Nanoconstructs by Increased Loading of G-quadruplex Aptamer

(2014) Duncan Hieu M. Dam et al.   NANO LETTERS

Cell Surface Nucleolin as a Target for Anti-Cancer Therapies

(2014) Marina Koutsioumpa et al.   Recent Patents on Anti-Cancer Drug Discovery

A phase II trial of AS1411 (a novel nucleolin-targeted DNA aptamer) in metastatic renal cell carcinoma

(2013) Jonathan E. Rosenberg et al.   INVESTIGATIONAL NEW DRUGS

Cancer risk in 680 000 people exposed to computed tomography scans in childhood or adolescence: data linkage study of 11 million Australians

(2013) J. D. Mathews et al.   BMJ-British Medical Journal

Direct Observation of Nanoparticle–Cancer Cell Nucleus Interactions

(2012) Duncan Hieu M. Dam et al.   ACS Nano

The heme oxygenase-1 inhibitor ZnPPIX induces non-canonical, Beclin 1-independent, autophagy through p38 MAPK pathway

(2012) C. Zhou et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Optical Aptasensors for the Analysis of the Vascular Endothelial Growth Factor (VEGF)

(2012) Ronit Freeman et al.   ANALYTICAL CHEMISTRY

Fluorescence Detection of DNA, Adenosine-5′-Triphosphate (ATP), and Telomerase Activity by Zinc(II)-Protoporphyrin IX/G-Quadruplex Labels

(2012) Zhanxia Zhang et al.   ANALYTICAL CHEMISTRY

Photocontrolled Targeted Drug Delivery: Photocaged Biologically Active Folic Acid as a Light-Responsive Tumor-Targeting Molecule

(2012) Nien-Chu Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Optimal strategies for the treatment of metastatic triple-negative breast cancer with currently approved agents

(2012) F. Andre et al.   ANNALS OF ONCOLOGY

A graphene functionalized electrochemical aptasensor for selective label-free detection of cancer cells

(2011) Lingyan Feng et al.   BIOMATERIALS

Amplified Analysis of DNA by the Autonomous Assembly of Polymers Consisting of DNAzyme Wires

(2011) Fuan Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aptamer-Based Tumor-Targeted Drug Delivery for Photodynamic Therapy

(2010) Yen-An Shieh et al.   ACS Nano

Breaking down the barriers: siRNA delivery and endosome escape

(2010) M. Dominska et al.   JOURNAL OF CELL SCIENCE

In vitro Studies of Functionalized Mesoporous Silica Nanoparticles for Photodynamic Therapy

(2009) Hsiung-Lin Tu et al.   ADVANCED MATERIALS

Mechanisms of tumor resistance to EGFR-targeted therapies

(2009) Elizabeth A Hopper-Borge et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Mesoporous silica nanoparticles functionalized with an oxygen-sensing probe for cell photodynamic therapy: potential cancer theranostics

(2009) Shih-Hsun Cheng et al.   JOURNAL OF MATERIALS CHEMISTRY

Exploring the Differential Recognition of DNA G-Quadruplex Targets by Small Molecules Using Dynamic Combinatorial Chemistry

(2008) Anthony Bugaut et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Zinc protoporphyrin IX, a heme oxygenase-1 inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice

(2008) Dominika Nowis et al.   BMC CANCER

G-Quadruplexes: Targets in Anticancer Drug Design

(2008) Tian-miao Ou et al.   ChemMedChem

Cell-surface nucleolin is a signal transducing P-selectin binding protein for human colon carcinoma cells

(2008) E. Merit Reyes-Reyes et al.   EXPERIMENTAL CELL RESEARCH

Folate receptor alpha as a tumor target in epithelial ovarian cancer

(2008) Kimberly R. Kalli et al.   GYNECOLOGIC ONCOLOGY

Imaging and imagination: understanding the endo-lysosomal system

(2008) Eline Meel et al.   HISTOCHEMISTRY AND CELL BIOLOGY