Cardiomyocyte-specific Txnip C247S mutation improves left ventricular functional reserve in streptozotocin-induced diabetic mice

Txnip C247S mutation protects the heart against acute myocardial infarction

(2021) Yoshinobu Nakayama et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Thioredoxin-Interacting Protein as a Novel Potential Therapeutic Target in Diabetes Mellitus and Its Underlying Complications

(2020) Dawit Zewdu Wondafrash et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Cardiovascular Risk in Type 1 Diabetes Mellitus

(2019) Jonathan Schofield et al.   Diabetes Therapy

Guidelines for measuring cardiac physiology in mice

(2018) Merry L. Lindsey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Diabetes pathogenic mechanisms and potential new therapies based upon a novel target called TXNIP

(2018) Lance Thielen et al.   Current Opinion in Endocrinology Diabetes and Obesity

Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization

(2018) William J. Sullivan et al.   CELL

Methods to identify the substrates of thiol‐disulfide oxidoreductases

(2018) Takushi Fujimoto et al.   PROTEIN SCIENCE

Phosphorylation of TXNIP by AKT Mediates Acute Influx of Glucose in Response to Insulin

(2017) Althea N. Waldhart et al.   Cell Reports

Deletion of thioredoxin-interacting protein improves cardiac inotropic reserve in the streptozotocin-induced diabetic heart

(2016) Ronald B. Myers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Housekeeping proteins: How useful are they in skeletal muscle diabetes studies and muscle hypertrophy models?

(2016) Marco Aurélio Salomão Fortes et al.   ANALYTICAL BIOCHEMISTRY

Diabetes regulates fructose absorption through thioredoxin-interacting protein

(2016) James R Dotimas et al.   eLife

Thioredoxin-2 Inhibits Mitochondrial Reactive Oxygen Species Generation and Apoptosis Stress Kinase-1 Activity to Maintain Cardiac Function

(2015) Q. Huang et al.   CIRCULATION

Thioredoxin-Interacting Protein Deficiency Protects against Diabetic Nephropathy

(2015) A. Shah et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

AMPK-Dependent Degradation of TXNIP upon Energy Stress Leads to Enhanced Glucose Uptake via GLUT1

(2013) Ning Wu et al.   MOLECULAR CELL

Glutathione/thioredoxin systems modulate mitochondrial H2O2emission: An experimental-computational study

(2012) Miguel Antonio Aon et al.   JOURNAL OF GENERAL PHYSIOLOGY

Thioredoxin Interacting Protein: Redox Dependent and Independent Regulatory Mechanisms

(2011) Oded N. Spindel et al.   ANTIOXIDANTS & REDOX SIGNALING

Thioredoxin Reductase-2 Is Essential for Keeping Low Levels of H2O2Emission from Isolated Heart Mitochondria

(2011) Brian A. Stanley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury

(2011) Jun Yoshioka et al.   JOURNAL OF CLINICAL INVESTIGATION

Single dose streptozotocin-induced diabetes: considerations for study design in islet transplantation models

(2011) M C Deeds et al.   LABORATORY ANIMALS

Thioredoxin-1 Gene Therapy Enhances Angiogenic Signaling and Reduces Ventricular Remodeling in Infarcted Myocardium of Diabetic Rats

(2010) Samson Mathews Samuel et al.   CIRCULATION

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Deletion of the  -Arrestin Protein Txnip in Mice Promotes Adiposity and Adipogenesis While Preserving Insulin Sensitivity

(2010) W. A. Chutkow et al.   DIABETES

Diabetic cardiomyopathy, causes and effects

(2010) Sihem Boudina et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Disruption of TBP-2 ameliorates insulin sensitivity and secretion without affecting obesity

(2010) Eiji Yoshihara et al.   Nature Communications

Increased Glucose Uptake and Oxidation in Mouse Hearts Prevent High Fatty Acid Oxidation but Cause Cardiac Dysfunction in Diet-Induced Obesity

(2009) Jie Yan et al.   CIRCULATION

Thioredoxin-independent Regulation of Metabolism by the α-Arrestin Proteins

(2009) Parth Patwari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intracellular Shuttling and Mitochondrial Function of Thioredoxin-interacting Protein

(2009) Geetu Saxena et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity

(2009) M. R. Kaadige et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes

(2008) Junqin Chen et al.   FASEB JOURNAL

Txnip balances metabolic and growth signaling via PTEN disulfide reduction

(2008) S. T. Y. Hui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucose sensing by MondoA:Mlx complexes: A role for hexokinases and direct regulation of thioredoxin-interacting protein expression

(2008) C. A. Stoltzman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA