Txnip C247S mutation protects the heart against acute myocardial infarction

Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization

(2018) William J. Sullivan et al.   CELL

Acute Myocardial Infarction

(2017) Jeffrey L. Anderson et al.   NEW ENGLAND JOURNAL OF MEDICINE

UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization

(2017) Ryota Nakashima et al.   Scientific Reports

Deletion of thioredoxin-interacting protein improves cardiac inotropic reserve in the streptozotocin-induced diabetic heart

(2016) Ronald B. Myers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Thioredoxin-2 Inhibits Mitochondrial Reactive Oxygen Species Generation and Apoptosis Stress Kinase-1 Activity to Maintain Cardiac Function

(2015) Q. Huang et al.   CIRCULATION

HIF-1 reduces ischaemia–reperfusion injury in the heart by targeting the mitochondrial permeability transition pore

(2014) Sang-Ging Ong et al.   CARDIOVASCULAR RESEARCH

Cardiac Mitochondria and Reactive Oxygen Species Generation

(2014) Yeong-Renn Chen et al.   CIRCULATION RESEARCH

Thioredoxin-interacting protein regulates protein disulfide isomerases and endoplasmic reticulum stress

(2014) S. Lee et al.   EMBO Molecular Medicine

The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein

(2014) Jungwon Hwang et al.   Nature Communications

Thioredoxin 1 Is Essential for Sodium Sulfide–Mediated Cardioprotection in the Setting of Heart Failure

(2013) Chad K. Nicholson et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

α-Synuclein-mediated defense against oxidative stress via modulation of glutathione peroxidase

(2013) Hee Jung Koo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

AMPK-Dependent Degradation of TXNIP upon Energy Stress Leads to Enhanced Glucose Uptake via GLUT1

(2013) Ning Wu et al.   MOLECULAR CELL

Regulation of HIF-1α activity by overexpression of thioredoxin is independent of thioredoxin reductase status

(2013) Salvador Naranjo-Suarez et al.   MOLECULES AND CELLS

Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury

(2011) Jun Yoshioka et al.   JOURNAL OF CLINICAL INVESTIGATION

Deletion of the  -Arrestin Protein Txnip in Mice Promotes Adiposity and Adipogenesis While Preserving Insulin Sensitivity

(2010) W. A. Chutkow et al.   DIABETES

Thioredoxin 1 enhances neovascularization and reduces ventricular remodeling during chronic myocardial infarction: A study using thioredoxin 1 transgenic mice

(2010) Ram Sudheer Adluri et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Disruption of TBP-2 ameliorates insulin sensitivity and secretion without affecting obesity

(2010) Eiji Yoshihara et al.   Nature Communications

Avoidance of Transient Cardiomyopathy in Cardiomyocyte-Targeted Tamoxifen-Induced MerCreMer Gene Deletion Models

(2009) Norimichi Koitabashi et al.   CIRCULATION RESEARCH

Thioredoxin-independent Regulation of Metabolism by the α-Arrestin Proteins

(2009) Parth Patwari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intracellular Shuttling and Mitochondrial Function of Thioredoxin-interacting Protein

(2009) Geetu Saxena et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thioredoxin-Interacting Protein: A Critical Link Between Glucose Toxicity and  -Cell Apoptosis

(2008) J. Chen et al.   DIABETES