Magneto-Activation and Magnetic Resonance Imaging of Natural Killer Cells Labeled with Magnetic Nanocomplexes for the Treatment of Solid Tumors

NK cell-based cancer immunotherapy: from basic biology to clinical development

(2021) Sizhe Liu et al.   Journal of Hematology & Oncology

Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors

(2020) Enli Liu et al.   NEW ENGLAND JOURNAL OF MEDICINE

The NK cell–cancer cycle: advances and new challenges in NK cell–based immunotherapies

(2020) Tobias Bald et al.   NATURE IMMUNOLOGY

Cationic Nanoparticle-Mediated Activation of Natural Killer Cells for Effective Cancer Immunotherapy

(2020) Kwang-Soo Kim et al.   ACS Applied Materials & Interfaces

Chimeric antigen receptor-engineered natural killer cells for cancer immunotherapy

(2020) Ahmet Yilmaz et al.   Journal of Hematology & Oncology

FDA-approved ferumoxytol displays anti-leukaemia efficacy against cells with low ferroportin levels

(2019) Vicenta Trujillo-Alonso et al.   Nature Nanotechnology

Enhancement of natural killer cell cytotoxicity by using static magnetic field to increase their viability

(2019) Shu-Li Lin et al.   ELECTROMAGNETIC BIOLOGY AND MEDICINE

Natural Killer Cells as Key Players of Tumor Progression and Angiogenesis: Old and Novel Tools to Divert Their Pro-Tumor Activities into Potent Anti-Tumor Effects

(2019) Barbara Bassani et al.   Cancers

Cancer Immunotherapy Based on Natural Killer Cells: Current Progress and New Opportunities

(2019) Weilei Hu et al.   Frontiers in Immunology

Natural Killer Cell Therapy: A New Treatment Paradigm for Solid Tumors

(2019) Sooyeon Oh et al.   Cancers

Comprehensive characterization of tumor infiltrating natural killer cells and clinical significance in hepatocellular carcinoma based on gene expression profiles

(2019) Mei Wu et al.   BIOMEDICINE & PHARMACOTHERAPY

Harnessing NK Cells for Cancer Treatment

(2019) Paola Minetto et al.   Frontiers in Immunology

Magnetic Nanotweezers for Interrogating Biological Processes in Space and Time

(2018) Ji-wook Kim et al.   ACCOUNTS OF CHEMICAL RESEARCH

Actin retrograde flow controls natural killer cell response by regulating the conformation state of SHP‐1

(2018) Omri Matalon et al.   EMBO JOURNAL

Natural Killer cells immune response requires a minimal nanoscale distribution of activating antigens.

(2018) Yossi Keydar et al.   Nanoscale

MRI-guided interventional natural killer cell delivery for liver tumor treatment

(2018) Zhanliang Su et al.   Cancer Medicine

Signals Controlling Lytic Granule Polarization at the Cytotoxic Immune Synapse

(2018) Anna Kabanova et al.   Frontiers in Immunology

A multi-functional macrophage and tumor targeting gene delivery system for the regulation of macrophage polarity and reversal of cancer immunoresistance

(2018) Xiao-Yan He et al.   Nanoscale

Magnetic delivery of Fe3O4@polydopamine nanoparticle-loaded natural killer cells suggest a promising anticancer treatment

(2018) Liya Wu et al.   Biomaterials Science

Optical Imaging of Cellular Immunotherapy against Prostate Cancer

(2018) Sidhartha Tavri et al.   Molecular Imaging

In Vivo Magnetic Resonance Imaging and Optical Imaging Comparison of Viable and Nonviable Mesenchymal Stem Cells with a Bifunctional Label

(2018) Elizabeth Jane Sutton et al.   Molecular Imaging

Nanoscale Mechanosensing of Natural Killer Cells is Revealed by Antigen-Functionalized Nanowires

(2018) Guillaume Le Saux et al.   ADVANCED MATERIALS

The dynamics of magnetic nanoparticles exposed to non-heating alternating magnetic field in biochemical applications: theoretical study

(2017) Yuri I. Golovin et al.   JOURNAL OF NANOPARTICLE RESEARCH

Tumor-Associated Monocytes/Macrophages Impair NK-Cell Function via TGFβ1 in Human Gastric Cancer

(2017) Liu-sheng Peng et al.   Cancer Immunology Research

Developmental and Functional Control of Natural Killer Cells by Cytokines

(2017) Yang Wu et al.   Frontiers in Immunology

The Molecular Mechanism of Natural Killer Cells Function and Its Importance in Cancer Immunotherapy

(2017) Sourav Paul et al.   Frontiers in Immunology

Acidic pH-Triggered Drug-Eluting Nanocomposites for Magnetic Resonance Imaging-Monitored Intra-arterial Drug Delivery to Hepatocellular Carcinoma

(2016) Wooram Park et al.   ACS Applied Materials & Interfaces

Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing

(2016) Roshni Basu et al.   CELL

Liver-infiltrating CD11b−CD27− NK subsets account for NK-cell dysfunction in patients with hepatocellular carcinoma and are associated with tumor progression

(2016) Qiong-Fang Zhang et al.   Cellular & Molecular Immunology

Intratumoral Delivery of Immunotherapy—Act Locally, Think Globally

(2016) M. Angela Aznar et al.   JOURNAL OF IMMUNOLOGY

Early treatment of HER2-amplified brain tumors with targeted NK-92 cells and focused ultrasound improves survival

(2016) Ryan Alkins et al.   NEURO-ONCOLOGY

Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia

(2016) Rizwan Romee et al.   Science Translational Medicine

Harnessing NK Cell Memory for Cancer Immunotherapy

(2016) Todd A. Fehniger et al.   TRENDS IN IMMUNOLOGY

Stealth CD44-targeted hyaluronic acid supramolecular nanoassemblies for doxorubicin delivery: Probing the effect of uncovalent pegylation degree on cellular uptake and blood long circulation

(2015) Xiaopeng Han et al.   JOURNAL OF CONTROLLED RELEASE

Clinically applicable magnetic-labeling of natural killer cells for MRI of transcatheter delivery to liver tumors: preclinical validation for clinical translation

(2015) Kangan Li et al.   Nanomedicine

MRI Visible Drug Eluting Magnetic Microspheres for Transcatheter Intra-Arterial Delivery to Liver Tumors

(2015) Dong-Hyun Kim et al.   Theranostics

Increase of IFN-γ and TNF-γ production in CD107a + NK-92 cells co-cultured with cervical cancer cell lines pre-treated with the HO-1 inhibitor

(2014) Paulina Gómez-Lomelí et al.   Cancer Cell International

NK cell receptor imbalance and NK cell dysfunction in HBV infection and hepatocellular carcinoma

(2014) Cheng Sun et al.   Cellular & Molecular Immunology

Wiskott-Aldrich syndrome protein - dynamic regulation of actin homeostasis: from activation through function and signal termination in T lymphocytes

(2014) Omri Matalon et al.   IMMUNOLOGICAL REVIEWS

Poly(lactide-co-glycolide) microspheres for MRI-monitored transcatheter delivery of sorafenib to liver tumors

(2014) Jeane Chen et al.   JOURNAL OF CONTROLLED RELEASE

T-Cell and NK-Cell Infiltration into Solid Tumors: A Key Limiting Factor for Efficacious Cancer Immunotherapy

(2014) I. Melero et al.   Cancer Discovery

Degradable Hyaluronic Acid/Protamine Sulfate Interpolyelectrolyte Complexes as miRNA-Delivery Nanocapsules for Triple-Negative Breast Cancer Therapy

(2014) Shihua Wang et al.   Advanced Healthcare Materials

Image-Guided Local Delivery Strategies Enhance Therapeutic Nanoparticle Uptake in Solid Tumors

(2013) Samdeep K. Mouli et al.   ACS Nano

NK cell-based immunotherapy for malignant diseases

(2013) Min Cheng et al.   Cellular & Molecular Immunology

Efficient generation of human natural killer cell lines by viral transformation

(2013) B Vogel et al.   LEUKEMIA

Subcellular control of Rac-GTPase signalling by magnetogenetic manipulation inside living cells

(2013) F. Etoc et al.   Nature Nanotechnology

Generation of natural killer cells from hematopoietic stem cells in vitro for immunotherapy

(2012) Martha Luevano et al.   Cellular & Molecular Immunology

Influence of NK cell magnetic bead isolation methods on phenotype and function of murine NK cells

(2012) Kathrin Meinhardt et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Self-assembling nanocomplexes by combining ferumoxytol, heparin and protamine for cell tracking by magnetic resonance imaging

(2012) Mya S Thu et al.   NATURE MEDICINE

Magnetic nanoparticle–mediated massively parallel mechanical modulation of single-cell behavior

(2012) Peter Tseng et al.   NATURE METHODS

Human NK cell lytic granules and regulation of their exocytosis

(2012) Konrad Krzewski et al.   Frontiers in Immunology

Intraprocedural Transcatheter Intra-arterial Perfusion MRI as a Predictor of Tumor Response to Chemoembolization for Hepatocellular Carcinoma

(2011) Dingxin Wang et al.   ACADEMIC RADIOLOGY

Adoptive Transfer of Autologous Natural Killer Cells Leads to High Levels of Circulating Natural Killer Cells but Does Not Mediate Tumor Regression

(2011) M. R. Parkhurst et al.   CLINICAL CANCER RESEARCH

Mechanoresponsive system based on sub-micron chitosan-functionalized ferromagnetic disks

(2011) Dong-Hyun Kim et al.   JOURNAL OF MATERIALS CHEMISTRY

Dynamic molecular processes mediate cellular mechanotransduction

(2011) Brenton D. Hoffman et al.   NATURE

Natural Killer Cell Lytic Granule Secretion Occurs through a Pervasive Actin Network at the Immune Synapse

(2011) Gregory D. Rak et al.   PLOS BIOLOGY

FDA report: Ferumoxytol for intravenous iron therapy in adult patients with chronic kidney disease

(2010) Min Lu et al.   AMERICAN JOURNAL OF HEMATOLOGY

The interaction of human natural killer cells with either unpolarized or polarized macrophages results in different functional outcomes

(2010) F. Bellora et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The influence of ferucarbotran on the chondrogenesis of human mesenchymal stem cells

(2009) Tobias D. Henning et al.   Contrast Media & Molecular Imaging

Ferromagnetic microdisks as carriers for biomedical applications

(2009) E. A. Rozhkova et al.   JOURNAL OF APPLIED PHYSICS

Biofunctionalized magnetic-vortex microdiscs for targeted cancer-cell destruction

(2009) Dong-Hyun Kim et al.   NATURE MATERIALS

Relationship between CD107a expression and cytotoxic activity

(2008) Esin Aktas et al.   CELLULAR IMMUNOLOGY

Agglomeration and sedimentation of TiO2 nanoparticles in cell culture medium

(2008) Zouhir E. Allouni et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Cell tracking with optical imaging

(2008) Elizabeth J. Sutton et al.   EUROPEAN RADIOLOGY

Functions of natural killer cells

(2008) Eric Vivier et al.   NATURE IMMUNOLOGY

Tracking of [18F]FDG-labeled natural killer cells to HER2/neu-positive tumors

(2008) Reinhard Meier et al.   NUCLEAR MEDICINE AND BIOLOGY

Measuring molecular rupture forces between single actin filaments and actin-binding proteins

(2008) J. M. Ferrer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-21 activates human natural killer cells and modulates their surface receptor expression

(2007) Kresten Skak et al.   IMMUNOLOGY