The Molecular Mechanism of Natural Killer Cells Function and Its Importance in Cancer Immunotherapy
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Molecular Mechanism of Natural Killer Cells Function and Its Importance in Cancer Immunotherapy
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-09-13
DOI
10.3389/fimmu.2017.01124
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- NK Cell–derived Exosomes From NK Cells Previously Exposed to Neuroblastoma Cells Augment the Antitumor Activity of Cytokine-activated NK Cells
- (2017) Alireza Shoae-Hassani et al. JOURNAL OF IMMUNOTHERAPY
- MICA/IL-12: A novel bifunctional protein for killer cell activation
- (2017) Ashlee Tietje et al. ONCOLOGY REPORTS
- Multi-cellular natural killer (NK) cell clusters enhance NK cell activation through localizing IL-2 within the cluster
- (2017) Miju Kim et al. Scientific Reports
- High-efficiency lysis of cervical cancer by allogeneic NK cells derived from umbilical cord progenitors is independent of HLA status
- (2016) John P. Veluchamy et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- IL-21 Enhances Natural Killer Cell Response to Cetuximab-Coated Pancreatic Tumor Cells
- (2016) Elizabeth L. McMichael et al. CLINICAL CANCER RESEARCH
- CD19-CAR engineered NK-92 cells are sufficient to overcome NK cell resistance in B-cell malignancies
- (2016) Annette Romanski et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Role of KIR and CD16A genotypes in colorectal carcinoma genetic risk and clinical stage
- (2016) Angelica Canossi et al. Journal of Translational Medicine
- Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia
- (2016) Rizwan Romee et al. Science Translational Medicine
- IL-15 superagonist/IL-15RαSushi-Fc fusion complex (IL-15SA/IL-15RαSu-Fc; ALT-803) markedly enhances specific subpopulations of NK and memory CD8+ T cells, and mediates potent anti-tumor activity against murine breast and colon carcinomas
- (2016) Peter S. Kim et al. Oncotarget
- Adoptively transferred natural killer cells maintain long-term antitumor activity by epigenetic imprinting and CD4+ T cell help
- (2016) Jing Ni et al. OncoImmunology
- Intratumoral natural killer cells show reduced effector and cytolytic properties and control the differentiation of effector Th1 cells
- (2016) Sourav Paul et al. OncoImmunology
- How Do Cytotoxic Lymphocytes Kill Cancer Cells?
- (2015) L. Martinez-Lostao et al. CLINICAL CANCER RESEARCH
- Redistribution, Hyperproliferation, Activation of Natural Killer Cells and CD8 T Cells, and Cytokine Production During First-in-Human Clinical Trial of Recombinant Human Interleukin-15 in Patients With Cancer
- (2015) Kevin C. Conlon et al. JOURNAL OF CLINICAL ONCOLOGY
- ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma
- (2015) Congcong Zhang et al. JNCI-Journal of the National Cancer Institute
- Phase I clinical trial of autologous NK cell therapy using novel expansion method in patients with advanced digestive cancer
- (2015) Naoyuki Sakamoto et al. Journal of Translational Medicine
- CD56dimCD57+NKG2C+ NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT
- (2015) F Cichocki et al. LEUKEMIA
- ADP-ribose/TRPM2-mediated Ca2+ signaling is essential for cytolytic degranulation and antitumor activity of natural killer cells
- (2015) So-Young Rah et al. Scientific Reports
- ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma
- (2015) Congcong Zhang et al. JNCI-Journal of the National Cancer Institute
- Role of tumor necrosis factor superfamily in neuroinflammation and autoimmunity
- (2015) Sandip Sonar Frontiers in Immunology
- Effect of NKG2D ligand expression on host immune responses
- (2015) Marine Champsaur et al. IMMUNOLOGICAL REVIEWS
- CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells
- (2015) Jianfeng Han et al. Scientific Reports
- Myeloid Expression of Adenosine A2A Receptor Suppresses T and NK Cell Responses in the Solid Tumor Microenvironment
- (2014) C. Cekic et al. CANCER RESEARCH
- A phase II trial of pan-KIR2D blockade with IPH2101 in smoldering multiple myeloma
- (2014) N. Korde et al. HAEMATOLOGICA
- Two Novel NKG2D Ligands of the Mouse H60 Family with Differential Expression Patterns and Binding Affinities to NKG2D
- (2014) A. Takada et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Priming of NK Cells by IL-18
- (2014) J. Chaix et al. JOURNAL OF IMMUNOLOGY
- Cancer-Expanded Myeloid-Derived Suppressor Cells Induce Anergy of NK Cells through Membrane-Bound TGF- 1
- (2014) H. Li et al. JOURNAL OF IMMUNOLOGY
- The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells
- (2014) Antoine Marçais et al. NATURE IMMUNOLOGY
- Tissue-resident natural killer cells and their potential diversity
- (2014) Dorothy K. Sojka et al. SEMINARS IN IMMUNOLOGY
- NK cells and T cells cooperate during the clinical course of colorectal cancer
- (2014) Giuseppe Sconocchia et al. OncoImmunology
- A Chimeric Receptor with NKG2D Specificity Enhances Natural Killer Cell Activation and Killing of Tumor Cells
- (2013) Y.-H. Chang et al. CANCER RESEARCH
- Natural killer cell-mediated contact sensitivity develops rapidly and depends on interferon-α, interferon-γ and interleukin-12
- (2013) Monika Majewska-Szczepanik et al. IMMUNOLOGY
- Natural cytotoxicity receptors and their ligands
- (2013) Philip H Kruse et al. IMMUNOLOGY AND CELL BIOLOGY
- p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells
- (2013) Alexandre Iannello et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Murine NK Cell Intrinsic Cytokine-Induced Memory-like Responses Are Maintained following Homeostatic Proliferation
- (2013) M. P. Keppel et al. JOURNAL OF IMMUNOLOGY
- CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma
- (2013) J Chu et al. LEUKEMIA
- Transfection of chimeric anti-CD138 gene enhances natural killer cell activation and killing of multiple myeloma cells
- (2013) Hua Jiang et al. Molecular Oncology
- Antigen Presenting Cell-Mediated Expansion of Human Umbilical Cord Blood Yields Log-Scale Expansion of Natural Killer Cells with Anti-Myeloma Activity
- (2013) Nina Shah et al. PLoS One
- The Critical Role of the Tumor Microenvironment in Shaping Natural Killer Cell-Mediated Anti-Tumor Immunity
- (2013) Joanna Baginska et al. Frontiers in Immunology
- A phase 1 trial of the anti-inhibitory KIR mAb IPH2101 for AML in complete remission
- (2012) N. Vey et al. BLOOD
- Cytokine activation induces human memory-like NK cells
- (2012) R. Romee et al. BLOOD
- Antitumor Immunotherapeutic and Toxic Properties of an HDL-Conjugated Chimeric IL-15 Fusion Protein
- (2012) M. C. Ochoa et al. CANCER RESEARCH
- Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity
- (2012) G. Pietra et al. CANCER RESEARCH
- Cancer immunoediting by the innate immune system in the absence of adaptive immunity
- (2012) Timothy O’Sullivan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Sustained effector function of IL-12/15/18–preactivated NK cells against established tumors
- (2012) Jing Ni et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Immune Surveillance Properties of Human NK Cell-Derived Exosomes
- (2012) L. Lugini et al. JOURNAL OF IMMUNOLOGY
- NK Cells are Required for Costimulatory Blockade Induced Tolerance to Vascularized Allografts
- (2012) William van der Touw et al. TRANSPLANTATION
- Natural killer cell distribution and trafficking in human tissues
- (2012) Paolo Carrega et al. Frontiers in Immunology
- Successful transfer of alloreactive haploidentical KIR ligand-mismatched natural killer cells after infusion in elderly high risk acute myeloid leukemia patients
- (2011) A. Curti et al. BLOOD
- Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function
- (2011) B. Foley et al. BLOOD
- Adoptive Transfer of Autologous Natural Killer Cells Leads to High Levels of Circulating Natural Killer Cells but Does Not Mediate Tumor Regression
- (2011) M. R. Parkhurst et al. CLINICAL CANCER RESEARCH
- NK cells engineered to express a GD2-specific antigen receptor display built-in ADCC-like activity against tumour cells of neuroectodermal origin
- (2011) Ruth Esser et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Origin, phenotype and function of human natural killer cells in pregnancy
- (2011) Paola Vacca et al. TRENDS IN IMMUNOLOGY
- A phase II study of allogeneic natural killer cell therapy to treat patients with recurrent ovarian and breast cancer
- (2010) Melissa A. Geller et al. CYTOTHERAPY
- Multiple Mechanisms Downstream of TLR-4 Stimulation Allow Expression of NKG2D Ligands To Facilitate Macrophage/NK Cell Crosstalk
- (2010) P. Eissmann et al. JOURNAL OF IMMUNOLOGY
- Critical role for the chemokine receptor CXCR6 in NK cell–mediated antigen-specific memory of haptens and viruses
- (2010) Silke Paust et al. NATURE IMMUNOLOGY
- Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors
- (2009) Y. T. Bryceson et al. BLOOD
- Regulation of human NK-cell cytokine and chemokine production by target cell recognition
- (2009) C. Fauriat et al. BLOOD
- 2B4 (CD244) Signaling by Recombinant Antigen-specific Chimeric Receptors Costimulates Natural Killer Cell Activation to Leukemia and Neuroblastoma Cells
- (2009) B. Altvater et al. CLINICAL CANCER RESEARCH
- Natural killer cell cytotoxicity: how do they pull the trigger?
- (2009) Nicola J. Topham et al. IMMUNOLOGY
- Immune cells in the placental bed
- (2009) Judith N. Bulmer et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- Dendritic Cell-Derived Exosomes Promote Natural Killer Cell Activation and Proliferation: A Role for NKG2D Ligands and IL-15Rα
- (2009) Sophie Viaud et al. PLoS One
- Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity
- (2009) M. Balsamo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NK cell education: not an on-off switch but a tunable rheostat
- (2009) Petter Brodin et al. TRENDS IN IMMUNOLOGY
- HLA-E upregulation on IFN-γ-activated AML blasts impairs CD94/NKG2A-dependent NK cytolysis after haplo-mismatched hematopoietic SCT
- (2008) S Nguyen et al. BONE MARROW TRANSPLANTATION
- IL-21 induces in vivo immune activation of NK cells and CD8+ T cells in patients with metastatic melanoma and renal cell carcinoma
- (2008) Klaus Stensgaard Frederiksen et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Selective Induction of Expression of a Ligand for the NKG2D Receptor by Proteasome Inhibitors
- (2008) M. Vales-Gomez et al. CANCER RESEARCH
- Natural Killer Cell Accumulation in Tumors Is Dependent on IFN- and CXCR3 Ligands
- (2008) M. Wendel et al. CANCER RESEARCH
- Interleukin-12 improves cytotoxicity of natural killer cells via upregulated expression of NKG2D
- (2008) Cai Zhang et al. HUMAN IMMUNOLOGY
- Up on the tightrope: natural killer cell activation and inhibition
- (2008) Lewis L Lanier NATURE IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started