In Situ Covalent Functionalization of DNA Origami Virus-like Particles

DNA origami demonstrate the unique stimulatory power of single pMHCs as T cell antigens

(2021) Joschka Hellmeier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extrusion of RNA from a DNA-Origami-Based Nanofactory

(2020) Jaeseung Hahn et al.   ACS Nano

Precision-Guided Missile-Like DNA Nanostructure Containing Warhead and Guidance Control for Aptamer-Based Targeted Drug Delivery into Cancer Cells in Vitro and in Vivo

(2020) Changhe Ouyang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Opportunities, Barriers, and a Strategy for Overcoming Translational Challenges to Therapeutic Nucleic Acid Nanotechnology

(2020) Kirill A. Afonin et al.   ACS Nano

Role of nanoscale antigen organization on B-cell activation probed using DNA origami

(2020) Rémi Veneziano et al.   Nature Nanotechnology

Opportunities and challenges for the clinical translation of structured DNA assemblies as gene therapeutic delivery and vaccine vectors

(2020) Marina A. Dobrovolskaia et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

A DNA nanodevice-based vaccine for cancer immunotherapy

(2020) Shaoli Liu et al.   NATURE MATERIALS

Automated Sequence Design of 3D Polyhedral Wireframe DNA Origami with Honeycomb Edges

(2019) Hyungmin Jun et al.   ACS Nano

Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies

(2019) Alan Shaw et al.   Nature Nanotechnology

Autonomously designed free-form 2D DNA origami

(2019) Hyungmin Jun et al.   Science Advances

Chemistries for DNA Nanotechnology

(2019) Mikael Madsen et al.   CHEMICAL REVIEWS

Custom-Size, Functional, and Durable DNA Origami with Design-Specific Scaffolds

(2019) Floris A. S. Engelhardt et al.   ACS Nano

Programming Structured DNA Assemblies to Probe Biophysical Processes

(2019) Eike-Christian Wamhoff et al.   Annual Review of Biophysics

Controllable Covalent-Bound Nanoarchitectures from DNA Frames

(2019) Zhiwei Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Uptake and Fate of Fluorescently Labeled DNA Nanostructures in Cellular Environments: A Cautionary Tale

(2019) Aurélie Lacroix et al.   ACS Central Science

Bioproduction of pure, kilobase-scale single-stranded DNA

(2019) Tyson R. Shepherd et al.   Scientific Reports

Peptide Assembly Directed and Quantified Using Megadalton DNA Nanostructures

(2019) Juan Jin et al.   ACS Nano

Automated sequence design of 2D wireframe DNA origami with honeycomb edges

(2019) Hyungmin Jun et al.   Nature Communications

Hierarchical Assembly of Nucleic Acid/Coiled-Coil Peptide Nanostructures

(2019) Alex Buchberger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Programmable DNA Origami Platform for Organizing Intrinsically Disordered Nucleoporins within Nanopore Confinement

(2018) Patrick D. Ellis Fisher et al.   ACS Nano

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

(2018) Suping Li et al.   NATURE BIOTECHNOLOGY

DNA Nanostructures at the Interface with Biology

(2018) Katherine E. Bujold et al.   Chem

In vitro synthesis of gene-length single-stranded DNA

(2018) Rémi Veneziano et al.   Scientific Reports

Design of Modular Protein Tags for Orthogonal Covalent Bond Formation at Specific DNA Sequences

(2017) Thang Minh Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Control of enzyme reactions by a reconfigurable DNA nanovault

(2017) Guido Grossi et al.   Nature Communications

Oligolysine-based coating protects DNA nanostructures from low-salt denaturation and nuclease degradation

(2017) Nandhini Ponnuswamy et al.   Nature Communications

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

(2016) Jung Soo Suk et al.   ADVANCED DRUG DELIVERY REVIEWS

Sequence-Dependent Fluorescence of Cy3- and Cy5-Labeled Double-Stranded DNA

(2016) Nicole Kretschy et al.   BIOCONJUGATE CHEMISTRY

Cellular delivery of enzyme-loaded DNA origami

(2016) Ari Ora et al.   CHEMICAL COMMUNICATIONS

Optimized DNA “Nanosuitcases” for Encapsulation and Conditional Release of siRNA

(2016) Katherine E. Bujold et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-assembly of size-controlled liposomes on DNA nanotemplates

(2016) Yang Yang et al.   Nature Chemistry

Designer nanoscale DNA assemblies programmed from the top down

(2016) R. Veneziano et al.   SCIENCE

Purification of Functionalized DNA Origami Nanostructures

(2015) Alan Shaw et al.   ACS Nano

Assembly and Purification of Enzyme-Functionalized DNA Origami Structures

(2015) Christopher Timm et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA rendering of polyhedral meshes at the nanoscale

(2015) Erik Benson et al.   NATURE

Complex wireframe DNA origami nanostructures with multi-arm junction vertices

(2015) Fei Zhang et al.   Nature Nanotechnology

Placing molecules with Bohr radius resolution using DNA origami

(2015) Jonas J. Funke et al.   Nature Nanotechnology

Hierarchical assembly of metal nanoparticles, quantum dots and organic dyes using DNA origami scaffolds

(2013) Robert Schreiber et al.   Nature Nanotechnology

Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

(2013) J. Jardine et al.   SCIENCE

DNA nanostructure serum stability: greater than the sum of its parts

(2012) Justin W. Conway et al.   CHEMICAL COMMUNICATIONS

Interenzyme Substrate Diffusion for an Enzyme Cascade Organized on Spatially Addressable DNA Nanostructures

(2012) Jinglin Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

(2012) S. M. Douglas et al.   SCIENCE

Functional Patterning of DNA Origami by Parallel Enzymatic Modification

(2011) Kasper Jahn et al.   BIOCONJUGATE CHEMISTRY

DNA origami: a quantum leap for self-assembly of complex structures

(2011) Thomas Tørring et al.   CHEMICAL SOCIETY REVIEWS

Orthogonal Protein Decoration of DNA Origami

(2010) Barbara Saccà et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Click chemistry with DNA

(2010) Afaf H. El-Sagheer et al.   CHEMICAL SOCIETY REVIEWS

Immobilization and One-Dimensional Arrangement of Virus Capsids with Nanoscale Precision Using DNA Origami

(2010) Nicholas Stephanopoulos et al.   NANO LETTERS

Single-molecule chemical reactions on DNA origami

(2010) Niels V. Voigt et al.   Nature Nanotechnology

Self-assembly of a nanoscale DNA box with a controllable lid

(2009) Ebbe S. Andersen et al.   NATURE