Tetrahedral Framework Nucleic Acid Delivered RNA Therapeutics Significantly Attenuate Pancreatic Cancer Progression via Inhibition of CTR1-Dependent Copper Absorption

Tetrahedral Framework Nucleic Acids Loaded with Aptamer AS1411 for siRNA Delivery and Gene Silencing in Malignant Melanoma

(2021) Dexuan Xiao et al.   ACS Applied Materials & Interfaces

Improved Antiviral Activity of Classical Swine Fever Virus-Targeted siRNA by Tetrahedral Framework Nucleic Acid-Enhanced Delivery

(2021) Haisi Dong et al.   ACS Applied Materials & Interfaces

Enhanced Penetrability of a Tetrahedral Framework Nucleic Acid by Modification with iRGD for DOX-Targeted Delivery to Triple-Negative Breast Cancer

(2021) Mengting Liu et al.   ACS Applied Materials & Interfaces

Tetrahedral Framework Nucleic Acids Deliver Antimicrobial Peptides with Improved Effects and Less Susceptibility to Bacterial Degradation

(2020) Yuhao Liu et al.   NANO LETTERS

Smart Nanocarriers for the Delivery of Nucleic Acid‐based Therapeutics: A Comprehensive Review

(2020) Thiruganesh Ramasamy et al.   Biotechnology Journal

Progress in Biomedical Applications of Tetrahedral Framework Nucleic Acid-Based Functional Systems

(2020) Tao Zhang et al.   ACS Applied Materials & Interfaces

Tetrahedral framework nucleic acids as an advanced drug delivery system for oligonucleotide drugs

(2020) Yuhao Liu et al.   APL Materials

Framework nucleic acids as programmable carrier for transdermal drug delivery

(2019) Christian Wiraja et al.   Nature Communications

DNA nanostructures coordinate gene silencing in mature plants

(2019) Huan Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blockage of SLC31A1-dependent copper absorption increases pancreatic cancer cell autophagy to resist cell death

(2019) Ze Yu et al.   CELL PROLIFERATION

Development of Whole-Porcine Monoclonal Antibodies with Potent Neutralization Activity against Classical Swine Fever Virus from Single B Cells

(2019) Haisi Dong et al.   ACS Synthetic Biology

DNA Nanotechnology-Enabled Drug Delivery Systems

(2018) Qinqin Hu et al.   CHEMICAL REVIEWS

Role of copper transporters in copper homeostasis

(2018) Joseph R Prohaska   AMERICAN JOURNAL OF CLINICAL NUTRITION

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Recent Advances in Copper Intercalators as Anticancer Agents

(2018) C. Shobha Devi et al.   JOURNAL OF FLUORESCENCE

iRGD-guided tumor-penetrating nanocomplexes for therapeutic siRNA delivery to pancreatic cancer

(2018) Justin H. Lo et al.   MOLECULAR CANCER THERAPEUTICS

Concept and Development of Framework Nucleic Acids

(2018) Zhilei Ge et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Influencing the Tumor Microenvironment: A Phase II Study of Copper Depletion Using Tetrathiomolybdate in Patients with Breast Cancer at High Risk for Recurrence and in Preclinical Models of Lung Metastases

(2016) Nancy Chan et al.   CLINICAL CANCER RESEARCH

Pancreatic cancer

(2016) Terumi Kamisawa et al.   LANCET

Targeting copper in cancer therapy: ‘Copper That Cancer’

(2015) Delphine Denoyer et al.   Metallomics

Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation

(2015) Jing Wang et al.   Nature Chemistry

Developmental Self-Assembly of a DNA Tetrahedron

(2014) John P. Sadowski et al.   ACS Nano

Copper is required for oncogenic BRAF signalling and tumorigenesis

(2014) Donita C. Brady et al.   NATURE

Functional DNA Nanostructures for Theranostic Applications

(2013) Hao Pei et al.   ACCOUNTS OF CHEMICAL RESEARCH

Smart Drug Delivery Nanocarriers with Self-Assembled DNA Nanostructures

(2013) Jiang Li et al.   ADVANCED MATERIALS

Downregulation of gas5 increases pancreatic cancer cell proliferation by regulating CDK6

(2013) Xiongxiong Lu et al.   CELL AND TISSUE RESEARCH

In vitro cell migration and invasion assays

(2012) Nina Kramer et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Involvement of the phosphoinositide 3-kinase/Akt pathway in apoptosis induced by capsaicin in the human pancreatic cancer cell line PANC-1

(2012) JIAN-HONG ZHANG et al.   Oncology Letters

Carbon-ion radiation enhances migration ability and invasiveness of the pancreatic cancer cell, PANC-1, in vitro

(2011) Mayumi Fujita et al.   CANCER SCIENCE

miR-27a regulates the growth, colony formation and migration of pancreatic cancer cells by targeting Sprouty2

(2010) Yihui Ma et al.   CANCER LETTERS

MicroRNA-101, Down-regulated in Hepatocellular Carcinoma, Promotes Apoptosis and Suppresses Tumorigenicity

(2009) H. Su et al.   CANCER RESEARCH

Enhanced resistance of DNA nanostructures to enzymatic digestion

(2009) Jung-Won Keum et al.   CHEMICAL COMMUNICATIONS

Copper in diseases and treatments, and copper-based anticancer strategies

(2009) Francesco Tisato et al.   MEDICINAL RESEARCH REVIEWS

Copper homeostasis

(2009) Jason L. Burkhead et al.   NEW PHYTOLOGIST