Self-Reproduction and Darwinian Evolution in Autocatalytic Chemical Reaction Systems

Structured sequences emerge from random pool when replicated by templated ligation

(2021) Patrick W. Kudella et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Darwinian properties and their trade-offs in autocatalytic RNA reaction networks

(2021) Sandeep Ameta et al.   Nature Communications

Selection from a pool of self-assembling lipid replicators

(2020) Ignacio Colomer et al.   Nature Communications

On the conditions for mimicking natural selection in chemical systems

(2020) Grégoire Danger et al.   Nature Reviews Chemistry

Spontaneous formation of autocatalytic sets with self-replicating inorganic metal oxide clusters

(2020) Haralampos N. Miras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autocatalytic chemical networks at the origin of metabolism

(2020) Joana C. Xavier et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Nonenzymatic Metabolic Reactions and Life’s Origins

(2020) Kamila B. Muchowska et al.   CHEMICAL REVIEWS

An ecological framework for the analysis of prebiotic chemical reaction networks

(2020) Zhen Peng et al.   JOURNAL OF THEORETICAL BIOLOGY

Emergence of light-driven protometabolism on recruitment of a photocatalytic cofactor by a self-replicator

(2020) Guillermo Monreal Santiago et al.   Nature Chemistry

From self-replication to replicator systems en route to de novo life

(2020) Paul Adamski et al.   Nature Reviews Chemistry

Universal motifs and the diversity of autocatalytic systems

(2020) Alex Blokhuis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cooperative Ligation Breaks Sequence Symmetry and Stabilizes Early Molecular Replication

(2019) Shoichi Toyabe et al.   Physical Review X

A chemically fuelled self-replicator

(2019) Sarah M. Morrow et al.   Nature Communications

Template-directed RNA polymerization and enhanced ribozyme catalysis inside membraneless compartments formed by coacervates

(2019) Raghav R. Poudyal et al.   Nature Communications

What is special about autocatalysis?

(2019) Peter Schuster   MONATSHEFTE FUR CHEMIE

A chemically fueled non-enzymatic bistable network

(2019) Indrajit Maity et al.   Nature Communications

Coupled catabolism and anabolism in autocatalytic RNA sets

(2018) Simon Arsène et al.   NUCLEIC ACIDS RESEARCH

A transient self-assembling self-replicator

(2018) Ignacio Colomer et al.   Nature Communications

Origins of building blocks of life: A review

(2018) Norio Kitadai et al.   Geoscience Frontiers

Systems protobiology: origin of life in lipid catalytic networks

(2018) Doron Lancet et al.   Journal of the Royal Society Interface

Kinetic Selection of Template Polymer with Complex Sequences

(2018) Yoshiya J. Matsubara et al.   PHYSICAL REVIEW LETTERS

Compartmentalised RNA catalysis in membrane-free coacervate protocells

(2018) Björn Drobot et al.   Nature Communications

Analysis of in vitro evolution reveals the underlying distribution of catalytic activity among random sequences

(2017) Abe Pressman et al.   NUCLEIC ACIDS RESEARCH

Foldamer hypothesis for the growth and sequence differentiation of prebiotic polymers

(2017) Elizaveta Guseva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Topological and thermodynamic factors that influence the evolution of small networks of catalytic RNA species

(2017) Jessica A.M. Yeates et al.   RNA

Formose Reaction Controlled by a Copolymer of N,N-Dimethylacrylamide and 4-Vinylphenylboronic Acid

(2017) Tomohiro Michitaka et al.   Polymers

Design principles of autocatalytic cycles constrain enzyme kinetics and force low substrate saturation at flux branch points

(2017) Uri Barenholz et al.   eLife

Real-Time Detection of a Self-Replicating RNA Enzyme

(2016) Charles Olea et al.   MOLECULES

Diversification of self-replicating molecules

(2016) Jan W. Sadownik et al.   Nature Chemistry

Growth and division of active droplets provides a model for protocells

(2016) David Zwicker et al.   Nature Physics

Unbounded growth patterns of reproducing, competing polymers—similarities to biological evolution

(2016) Emanuel Gregor Worst et al.   NEW JOURNAL OF PHYSICS

Amplification of RNA by an RNA polymerase ribozyme

(2016) David P. Horning et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamics of prebiotic RNA reproduction illuminated by chemical game theory

(2016) Jessica A. M. Yeates et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribose and related sugars from ultraviolet irradiation of interstellar ice analogs

(2016) C. Meinert et al.   SCIENCE

Transient compartmentalization of RNA replicators prevents extinction due to parasites

(2016) S. Matsumura et al.   SCIENCE

From Chemical Gardens to Chemobrionics

(2015) Laura M. Barge et al.   CHEMICAL REVIEWS

Spontaneous emergence of autocatalytic information-coding polymers

(2015) Alexei V. Tkachenko et al.   JOURNAL OF CHEMICAL PHYSICS

Primordial evolvability: Impasses and challenges

(2015) Vera Vasas et al.   JOURNAL OF THEORETICAL BIOLOGY

Prebiotic network evolution: six key parameters

(2015) Philippe Nghe et al.   Molecular BioSystems

Freeze–thaw cycles as drivers of complex ribozyme assembly

(2015) Hannes Mutschler et al.   Nature Chemistry

Noise-Induced Mechanism for Biological Homochirality of Early Life Self-Replicators

(2015) Farshid Jafarpour et al.   PHYSICAL REVIEW LETTERS

Exponential self-replication enabled through a fibre elongation/breakage mechanism

(2015) Mathieu Colomb-Delsuc et al.   Nature Communications

Competition and Cooperation in Dynamic Replication Networks

(2014) Zehavit Dadon et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Formation of Monosaccharides: From the Formose Reaction towards Selective Synthesis

(2014) Irina V. Delidovich et al.   ChemSusChem

Physical autocatalysis driven by a bond-forming thiol–ene reaction

(2014) Andrew J. Bissette et al.   Nature Communications

A High-Resolution Structure that Provides Insight into Coiled-Coil Thiodepsipeptide Dynamic Chemistry

(2013) Zehavit Dadon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Uncovering the Selection Criteria for the Emergence of Multi-Building-Block Replicators from Dynamic Combinatorial Libraries

(2013) Morteza Malakoutikhah et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamic Combinatorial Libraries: From Exploring Molecular Recognition to Systems Chemistry

(2013) Jianwei Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Competition between model protocells driven by an encapsulated catalyst

(2013) Katarzyna Adamala et al.   Nature Chemistry

Next-generation sequencing reveals how RNA catalysts evolve from random space

(2013) Sandeep Ameta et al.   NUCLEIC ACIDS RESEARCH

Mechanism of IAPP amyloid fibril formation involves an intermediate with a transient  -sheet

(2013) L. E. Buchanan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Escalation of polymerization in a thermal gradient

(2013) C. B. Mast et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonenzymatic Template-Directed RNA Synthesis Inside Model Protocells

(2013) K. Adamala et al.   SCIENCE

Darwinian evolution in a translation-coupled RNA replication system within a cell-like compartment

(2013) Norikazu Ichihashi et al.   Nature Communications

Dynamic Molecular Networks: From Synthetic Receptors to Self-Replicators

(2012) Sijbren Otto   ACCOUNTS OF CHEMICAL RESEARCH

The Structure of Autocatalytic Sets: Evolvability, Enablement, and Emergence

(2012) Wim Hordijk et al.   ACTA BIOTHEORETICA

Evolution before genes

(2012) Vera Vasas et al.   Biology Direct

Spontaneous network formation among cooperative RNA replicators

(2012) Nilesh Vaidya et al.   NATURE

Prebiotically plausible mechanisms increase compositional diversity of nucleic acid sequences

(2012) Julien Derr et al.   NUCLEIC ACIDS RESEARCH

The Origin of Large Molecules in Primordial Autocatalytic Reaction Networks

(2012) Varun Giri et al.   PLoS One

Chemical and light triggering of peptide networks under partial thermodynamic control

(2011) Zehavit Dadon et al.   CHEMICAL COMMUNICATIONS

Autocatalyses

(2011) Raphaël Plasson et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Ribozyme-Catalyzed Transcription of an Active Ribozyme

(2011) A. Wochner et al.   SCIENCE

Defining Life

(2010) Steven A. Benner   ASTROBIOLOGY

A Review on Inorganic Nanostructure Self-Assembly

(2010) Yuehui Wang et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Lack of evolvability in self-sustaining autocatalytic networks constraints metabolism-first scenarios for the origin of life

(2010) V. Vasas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mineral Surfaces, Geochemical Complexities, and the Origins of Life

(2010) R. M. Hazen et al.   Cold Spring Harbor Perspectives in Biology

On the origin of life in the Zinc world: 1. Photosynthesizing, porous edifices built of hydrothermally precipitated zinc sulfide as cradles of life on Earth

(2009) Armen Y Mulkidjanian   Biology Direct

The smallest chemical reaction system with bistability

(2009) Thomas Wilhelm   BMC Systems Biology

Origin of Self-Replicating Biopolymers: Autocatalytic Feedback Can Jump-Start the RNA World

(2009) Meng Wu et al.   JOURNAL OF MOLECULAR EVOLUTION

Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions

(2009) Matthew W. Powner et al.   NATURE

Self-organized criticality of a catalytic reaction network under flow

(2009) Akinori Awazu et al.   PHYSICAL REVIEW E

Self-Sustained Replication of an RNA Enzyme

(2009) T. A. Lincoln et al.   SCIENCE

Explosive Percolation in Random Networks

(2009) D. Achlioptas et al.   SCIENCE

Prevolutionary dynamics and the origin of evolution

(2008) M. A. Nowak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Implausibility of Metabolic Cycles on the Prebiotic Earth

(2008) Leslie E Orgel   PLOS BIOLOGY