Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast

The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver

(2020) Natascha Hruschka et al.   ONCOGENE

Transcriptional regulation of normal human mammary cell heterogeneity and its perturbation in breast cancer

(2019) Davide Pellacani et al.   EMBO JOURNAL

Slide-seq: A scalable technology for measuring genome-wide expression at high spatial resolution

(2019) Samuel G. Rodriques et al.   SCIENCE

The clinical and biological significance of HER2 over-expression in breast ductal carcinoma in situ: a large study from a single institution

(2019) Islam M. Miligy et al.   BRITISH JOURNAL OF CANCER

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

Genomic landscape of ductal carcinoma in situ and association with progression

(2019) Chieh-Yu Lin et al.   BREAST CANCER RESEARCH AND TREATMENT

Tumor PIK3CA Genotype and Prognosis in Early-Stage Breast Cancer: A Pooled Analysis of Individual Patient Data

(2018) Dimitrios Zardavas et al.   JOURNAL OF CLINICAL ONCOLOGY

GATA3 zinc finger 2 mutations reprogram the breast cancer transcriptional network

(2018) Motoki Takaku et al.   Nature Communications

Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer

(2017) Jia-Min B Pang et al.   MODERN PATHOLOGY

GATA3 targets semaphorin 3B in mammary epithelial cells to suppress breast cancer progression and metastasis

(2017) P Shahi et al.   ONCOGENE

Ductal Carcinoma In Situ Biology, Biomarkers, and Diagnosis

(2017) Kylie L. Gorringe et al.   Frontiers in Oncology

Do LORIS Trial Eligibility Criteria Identify a Ductal Carcinoma In Situ Patient Population at Low Risk of Upgrade to Invasive Carcinoma?

(2016) Melissa Pilewskie et al.   ANNALS OF SURGICAL ONCOLOGY

Visualization and analysis of gene expression in tissue sections by spatial transcriptomics

(2016) P. L. Stahl et al.   SCIENCE

Feasibility of a prospective, randomised, open-label, international multicentre, phase III, non-inferiority trial to assess the safety of active surveillance for low risk ductal carcinoma in situ – The LORD study

(2015) Lotte E. Elshof et al.   EUROPEAN JOURNAL OF CANCER

Reactivation of multipotency by oncogenic PIK3CA induces breast tumour heterogeneity

(2015) Alexandra Van Keymeulen et al.   NATURE

PIK3CAH1047R induces multipotency and multi-lineage mammary tumours

(2015) Shany Koren et al.   NATURE

Survival Benefit of Breast Surgery for Low-Grade Ductal Carcinoma In Situ

(2015) Yasuaki Sagara et al.   JAMA Surgery

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Prioritization of Research Addressing Management Strategies for Ductal Carcinoma In Situ

(2014) Jennifer M. Gierisch et al.   ANNALS OF INTERNAL MEDICINE

Sequenza: allele-specific copy number and mutation profiles from tumor sequencing data

(2014) F. Favero et al.   ANNALS OF ONCOLOGY

PyClone: statistical inference of clonal population structure in cancer

(2014) Andrew Roth et al.   NATURE METHODS

TCC: an R package for comparing tag count data with robust normalization strategies

(2013) Jianqiang Sun et al.   BMC BIOINFORMATICS

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

(2013) Kristian Cibulskis et al.   NATURE BIOTECHNOLOGY

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Biological Markers in DCIS and Risk of Breast Recurrence: A Systematic Review

(2012) Sara A. Lari et al.   Journal of Cancer

Frequent pathway mutations of splicing machinery in myelodysplasia

(2011) Kenichi Yoshida et al.   NATURE

A new pathological system for grading DCIS with improved prediction of local recurrence: results from the UKCCCR/ANZ DCIS trial

(2010) S E Pinder et al.   BRITISH JOURNAL OF CANCER

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

The molecular pathology of breast cancer progression

(2010) Alessandro Bombonati et al.   JOURNAL OF PATHOLOGY

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

CDK Inhibitor p18INK4c Is a Downstream Target of GATA3 and Restrains Mammary Luminal Progenitor Cell Proliferation and Tumorigenesis

(2009) Xin-Hai Pei et al.   CANCER CELL

GATA3 in development and cancer differentiation: Cells GATA have it!

(2009) Jonathan Chou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

GATA3 inhibits breast cancer growth and pulmonary breast cancer metastasis

(2009) A B Dydensborg et al.   ONCOGENE

Gene and chromosomal alterations in sporadic breast cancer: correlation with histopathological features and implications for genesis and progression

(2009) Hitoshi Tsuda   Breast Cancer

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

GATA-3 Links Tumor Differentiation and Dissemination in a Luminal Breast Cancer Model

(2008) Hosein Kouros-Mehr et al.   CANCER CELL

Is Breast Tumor Progression Really Linear?

(2008) K. Polyak   CLINICAL CANCER RESEARCH

Ductal Carcinoma in Situ: State of the Science and Roadmap to Advance the Field

(2008) Henry M. Kuerer et al.   JOURNAL OF CLINICAL ONCOLOGY