Common variants at 21q22.3 locus influence MX1 and TMPRSS2 gene expression and susceptibility to severe COVID-19

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

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The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic

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Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area

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Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy

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First comprehensive computational analysis of functional consequences of TMPRSS2 SNPs in susceptibility to SARS-CoV-2 among different populations

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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

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A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells

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Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells

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ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in Italy

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New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis

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ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population

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Presence of Genetic Variants Among Young Men With Severe COVID-19

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Genomewide Association Study of Severe Covid-19 with Respiratory Failure

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Genetic Analysis of the Coronavirus SARS-CoV-2 Host Protease TMPRSS2 in Different Populations

(2020) Roberta Russo et al.   Frontiers in Genetics

What chances do children have against COVID-19? Is the answer hidden within the thymus?

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Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

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Susceptibility to severe COVID-19

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The role of the thymus in COVID-19 disease severity: implications for antibody treatment and immunization

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COVID-19 and Genetic Variants of Protein Involved in the SARS-CoV-2 Entry into the Host Cells

(2020) Andrea Latini et al.   Genes

SARS-CoV-2 Infection Boosts MX1 Antiviral Effector in COVID-19 Patients

(2020) Juan Bizzotto et al.   iScience

Ventilation of coronavirus disease 2019 patients

(2020) Giacomo Grasselli et al.   Current Opinion in Critical Care

ACE2 and TMPRSS2 polymorphisms in various diseases with special reference to its impact on COVID-19 disease

(2020) HariOm Singh et al.   MICROBIAL PATHOGENESIS

Genetic mechanisms of critical illness in Covid-19

(2020) Erola Pairo-Castineira et al.   NATURE

Interferon-Inducible Myxovirus Resistance Proteins: Potential Biomarkers for Differentiating Viral from Bacterial Infections

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Host genetics of severe influenza: from mouse Mx1 to human IRF7

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Human IFNAR2 deficiency: Lessons for antiviral immunity

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Systematic identification of trans eQTLs as putative drivers of known disease associations

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IFN-α Is Constitutively Expressed in the Human Thymus, but Not in Peripheral Lymphoid Organs

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Global Analysis of the Impact of Environmental Perturbation on cis-Regulation of Gene Expression

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Efficient Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by the Transmembrane Protease TMPRSS2

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