Dimethyl fumarate prevents ferroptosis to attenuate acute kidney injury by acting on NRF2

Acute kidney injury pathology and pathophysiology: a retrospective review

(2020) Joseph P Gaut et al.   Clinical Kidney Journal

NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

(2019) Matthew Dodson et al.   Redox Biology

Emerging Role of Ferroptosis in Acute Kidney Injury

(2019) Zhaoxin Hu et al.   Oxidative Medicine and Cellular Longevity

Effect of dimethyl fumarate on renal disease progression in a genetic ortholog of nephronophthisis

(2018) Oliver Oey et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Pharmacodynamics of Dimethyl Fumarate Are Tissue Specific and Involve NRF2-Dependent and -Independent Mechanisms

(2016) Melanie S. Brennan et al.   ANTIOXIDANTS & REDOX SIGNALING

Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid–Induced AKI

(2016) Diego Martin-Sanchez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Dimethylfumarate Attenuates Renal Fibrosis via NF-E2-Related Factor 2-Mediated Inhibition of Transforming Growth Factor-β/Smad Signaling

(2012) Chang Joo Oh et al.   PLoS One