Caspase-1 Abrogates the Salutary Effects of Hypertrophic Preconditioning in Pressure Overload Hearts via IL-1β and IL-18

Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function

(2020) Li Wang et al.   NATURE CELL BIOLOGY

Double knockout of Akt2 and AMPK accentuates high fat diet-induced cardiac anomalies through a cGAS-STING-mediated mechanism

(2020) Yan Gong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cells of the adult human heart

(2020) Monika Litviňuková et al.   NATURE

Variations in Energy Metabolism Precede Alterations in Cardiac Structure and Function in Hypertrophic Preconditioning

(2020) Jian Wu et al.   Frontiers in Cardiovascular Medicine

Inflammation and NLRP3 Inflammasome Activation Initiated in Response to Pressure Overload by Ca 2+ /Calmodulin-Dependent Protein Kinase II δ Signaling in Cardiomyocytes Are Essential for Adverse Cardiac Remodeling

(2019) Takeshi Suetomi et al.   CIRCULATION

Inflammation and fibrosis in murine models of heart failure

(2019) Lucas Bacmeister et al.   BASIC RESEARCH IN CARDIOLOGY

Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension

(2019) Camilla Udjus et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Biomarkers of Inflammation in Left Ventricular Diastolic Dysfunction

(2019) Mihaela Mocan et al.   DISEASE MARKERS

Caspase-1 as Molecular Key in Cardiac Remodeling during Cardiorenal Syndrome Type 3 in the Murine Model

(2019) Mayra Trentin-Sonoda et al.   CURRENT MOLECULAR MEDICINE

Gender Differences in Cardiac Hypertrophy

(2019) Jian Wu et al.   Journal of Cardiovascular Translational Research

Caspase-1 regulates Ang II-induced cardiomyocyte hypertrophy via up-regulation of IL-1β

(2018) Yunlong Bai et al.   BIOSCIENCE REPORTS

NLRP3 Inflammasome and the IL-1 Pathway in Atherosclerosis

(2018) Alena Grebe et al.   CIRCULATION RESEARCH

ALDH2 protects against high fat diet-induced obesity cardiomyopathy and defective autophagy: role of CaM kinase II, histone H3K9 methyltransferase SUV39H, Sirt1, and PGC-1α deacetylation

(2018) Shuyi Wang et al.   INTERNATIONAL JOURNAL OF OBESITY

Tet2-Mediated Clonal Hematopoiesis Accelerates Heart Failure Through a Mechanism Involving the IL-1β/NLRP3 Inflammasome

(2018) Soichi Sano et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Mechanisms of physiological and pathological cardiac hypertrophy

(2018) Michinari Nakamura et al.   Nature Reviews Cardiology

Inflammasome, pyroptosis, and cytokines in myocardial ischemia-reperfusion injury

(2018) Stefano Toldo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Role of pyroptosis in cardiovascular disease

(2018) Zeng Zhaolin et al.   CELL PROLIFERATION

Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice

(2018) Lingfei Li et al.   EBioMedicine

Heat-shock protein 90 modulates cardiac ventricular hypertrophy via activation of MAPK pathway

(2018) Shoko Tamura et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IL-18 cleavage triggers cardiac inflammation and fibrosis upon β-adrenergic insult

(2017) Han Xiao et al.   EUROPEAN HEART JOURNAL

A Review of the Molecular Mechanisms Underlying the Development and Progression of Cardiac Remodeling

(2017) Leonardo Schirone et al.   Oxidative Medicine and Cellular Longevity

Effects of Heart Rate and Anesthetic Timing on High-Resolution Echocardiographic Assessment Under Isoflurane Anesthesia in Mice

(2017) Jian Wu et al.   JOURNAL OF ULTRASOUND IN MEDICINE

Dual-specificity phosphatase 14 protects the heart from aortic banding-induced cardiac hypertrophy and dysfunction through inactivation of TAK1-P38MAPK/-JNK1/2 signaling pathway

(2016) Chang-Yi Li et al.   BASIC RESEARCH IN CARDIOLOGY

Pyroptosis as a Regulated Form of Necrosis

(2016) Jun-ichi Abe et al.   CIRCULATION RESEARCH

Myocardial Hypertrophic Preconditioning Attenuates Cardiomyocyte Hypertrophy and Slows Progression to Heart Failure Through Upregulation of S100A8/A9

(2015) X. Wei et al.   CIRCULATION

Molecular Basis of Cardioprotection: Signal Transduction in Ischemic Pre-, Post-, and Remote Conditioning

(2015) G. Heusch   CIRCULATION RESEARCH

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Angiogenesis and Cardiac Hypertrophy

(2014) Toru Oka et al.   CIRCULATION RESEARCH

Pressure overload induces IL-18 and IL-18R expression, but markedly suppresses IL-18BP expression in a rabbit model. IL-18 potentiates TNF-α-induced cardiomyocyte death

(2014) Tadashi Yoshida et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Comparison between adenosine and isoflurane for assessing the coronary flow reserve in mouse models of left ventricular pressure and volume overload

(2012) Jieyun You et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Early Estimation of Left Ventricular Systolic Pressure and Prediction of Successful Aortic Constriction in a Mouse Model of Pressure Overload by Ultrasound Biomicroscopy

(2012) Jian Wu et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Prevalence of left-ventricular hypertrophy in hypertension: an updated review of echocardiographic studies

(2011) C Cuspidi et al.   JOURNAL OF HUMAN HYPERTENSION

Molecular mechanisms of left ventricular hypertrophy (LVH) in systemic hypertension (SH)—possible therapeutic perspectives

(2011) Federico Cacciapuoti   Journal of the American Society of Hypertension

The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse

(2011) E. Mezzaroma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA