ALDH2 protects against high fat diet-induced obesity cardiomyopathy and defective autophagy: role of CaM kinase II, histone H3K9 methyltransferase SUV39H, Sirt1, and PGC-1α deacetylation
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
ALDH2 protects against high fat diet-induced obesity cardiomyopathy and defective autophagy: role of CaM kinase II, histone H3K9 methyltransferase SUV39H, Sirt1, and PGC-1α deacetylation
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF OBESITY
Volume 42, Issue 5, Pages 1073-1087
Publisher
Springer Nature
Online
2018-03-13
DOI
10.1038/s41366-018-0030-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Modeling insulin resistance in rodents by alterations in diet: what have high-fat and high-calorie diets revealed?
- (2018) Lewin Small et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart Disease
- (2017) Connor A. Emdin et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Ablation of Akt2 prevents paraquat-induced myocardial mitochondrial injury and contractile dysfunction: Role of Nrf2
- (2017) Shuyi Wang et al. TOXICOLOGY LETTERS
- The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction
- (2017) Guang Yang et al. Nature Communications
- Clinical utility of metabolic syndrome severity scores: considerations for practitioners
- (2017) Mark D DeBoer et al. Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
- Associations between aldehyde dehydrogenase 2 (ALDH2) rs671 genetic polymorphisms, lifestyles and hypertension risk in Chinese Han people
- (2017) Cong Ma et al. Scientific Reports
- Glucolipotoxicity diminishes cardiomyocyte TFEB and inhibits lysosomal autophagy during obesity and diabetes
- (2016) Purvi C. Trivedi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Autophagy in cardiac metabolic control: Novel mechanisms for cardiovascular disorders
- (2016) Yufei Yang et al. CELL BIOLOGY INTERNATIONAL
- Adiponectin promotes VEGF-C-dependent lymphangiogenesis by inhibiting miR-27b through a CaMKII/AMPK/p38 signaling pathway in human chondrosarcoma cells
- (2016) C.-Y. Huang et al. CLINICAL SCIENCE
- Infant Eating Behaviors and Risk for Overweight
- (2016) Julie C. Lumeng JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Epigenetics and obesity cardiomyopathy: From pathophysiology to prevention and management
- (2016) Yingmei Zhang et al. PHARMACOLOGY & THERAPEUTICS
- Toll-like receptor 4 knockout alleviates paraquat-induced cardiomyocyte contractile dysfunction through an autophagy-dependent mechanism
- (2016) Shuyi Wang et al. TOXICOLOGY LETTERS
- Mitochondrial aldehyde dehydrogenase obliterates insulin resistance-induced cardiac dysfunction through deacetylation of PGC-1α
- (2016) Nan Hu et al. Oncotarget
- Aldehyde dehydrogenase 2 activation in aged heart improves the autophagy by reducing the carbonyl modification on SIRT1
- (2016) Bing Wu et al. Oncotarget
- The role of sirtuins in cardiac disease
- (2015) Shouji Matsushima et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- A novel protective mechanism for mitochondrial aldehyde dehydrogenase (ALDH2) in type i diabetes-induced cardiac dysfunction: Role of AMPK-regulated autophagy
- (2015) Yuli Guo et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Aldehyde dedydrogenase-2 plays a beneficial role in ameliorating chronic alcohol-induced hepatic steatosis and inflammation through regulation of autophagy
- (2015) Rui Guo et al. JOURNAL OF HEPATOLOGY
- The Protective Effects of Salidroside from Exhaustive Exercise-Induced Heart Injury by Enhancing thePGC-1α–NRF1/NRF2Pathway and Mitochondrial Respiratory Function in Rats
- (2015) Zheng Ping et al. Oxidative Medicine and Cellular Longevity
- Dietary Intervention for Overweight and Obese Adults: Comparison of Low-Carbohydrate and Low-Fat Diets. A Meta-Analysis
- (2015) Jonathan Sackner-Bernstein et al. PLoS One
- Caffeine promotes autophagy in skeletal muscle cells by increasing the calcium-dependent activation of AMP-activated protein kinase
- (2014) T.S. Mathew et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Potentiating mitochondrial aldehyde dehydrogenase 2 to treat post-infarction heart failure
- (2014) A. Yavari et al. CARDIOVASCULAR RESEARCH
- Ca2+ mishandling and cardiac dysfunction in obesity and insulin resistance: Role of oxidative stress
- (2014) Karla Carvajal et al. CELL CALCIUM
- Mitochondrial aldehyde dehydrogenase 2 accentuates aging-induced cardiac remodeling and contractile dysfunction: role of AMPK, Sirt1, and mitochondrial function
- (2014) Yingmei Zhang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Aldehyde dehydrogenase 2 ameliorates doxorubicin-induced myocardial dysfunction through detoxification of 4-HNE and suppression of autophagy
- (2014) Aijun Sun et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Targeting Aldehyde Dehydrogenase 2: New Therapeutic Opportunities
- (2014) Che-Hong Chen et al. PHYSIOLOGICAL REVIEWS
- Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system
- (2014) A. D. Ebert et al. Science Translational Medicine
- Mitochondrial Aldehyde Dehydrogenase 2 Plays Protective Roles in Heart Failure After Myocardial Infarction via Suppression of the Cytosolic JNK/p53 Pathway in Mice
- (2014) Aijun Sun et al. Journal of the American Heart Association
- Metabolism leaves its mark on the powerhouse: recent progress in post-translational modifications of lysine in mitochondria
- (2014) Kyriakos N. Papanicolaou et al. Frontiers in Physiology
- Oxidative activation of Ca2+/calmodulin-activated kinase II mediates ER stress-induced cardiac dysfunction and apoptosis
- (2013) Nathan D. Roe et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Activation of Calcium/Calmodulin-Dependent Protein Kinase II in Obesity Mediates Suppression of Hepatic Insulin Signaling
- (2013) Lale Ozcan et al. Cell Metabolism
- SIRT3 protects cardiomyocytes from oxidative stress-mediated cell death by activating NF-κB
- (2012) Chun-Juan Chen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mitochondrial aldehyde dehydrogenase (ALDH2) protects against streptozotocin-induced diabetic cardiomyopathy: role of GSK3β and mitochondrial function
- (2012) Yingmei Zhang et al. BMC Medicine
- Insulin-Like Growth Factor 1 Alleviates High-Fat Diet–Induced Myocardial Contractile Dysfunction
- (2012) Yingmei Zhang et al. HYPERTENSION
- Alterations in Glutathione Redox Metabolism, Oxidative Stress, and Mitochondrial Function in the Left Ventricle of Elderly Zucker Diabetic Fatty Rat Heart
- (2012) Haider Raza et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Sirtuins as regulators of metabolism and healthspan
- (2012) Riekelt H. Houtkooper et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitochondrial biogenesis and PGC-1α deacetylation by chronic treadmill exercise: differential response in cardiac and skeletal muscle
- (2011) Ling Li et al. BASIC RESEARCH IN CARDIOLOGY
- Role of Cardiac Steatosis and Lipotoxicity in Obesity Cardiomyopathy
- (2011) Yingmei Zhang et al. HYPERTENSION
- ALDH2 in alcoholic heart diseases: Molecular mechanism and clinical implications
- (2011) Yingmei Zhang et al. PHARMACOLOGY & THERAPEUTICS
- PGC-1 coactivators in the cardiovascular system
- (2011) Ian S. Patten et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Aldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde
- (2010) Heng Ma et al. EUROPEAN HEART JOURNAL
- Peroxisome Proliferator-activated Receptor γ Co-activator 1α (PGC-1α) and Sirtuin 1 (SIRT1) Reside in Mitochondria
- (2010) Katia Aquilano et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transgenic Overexpression of Aldehyde Dehydrogenase-2 Rescues Chronic Alcohol Intake–Induced Myocardial Hypertrophy and Contractile Dysfunction
- (2009) Thomas A. Doser et al. CIRCULATION
- PGC-1α and ERRα target gene downregulation is a signature of the failing human heart
- (2008) Smita Sihag et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More