Novel insights into conjugation of antitumor-active unsymmetrical bisacridine C-2028 with glutathione: characteristics of non-enzymatic and glutathione S-transferase-mediated reactions

New Unsymmetrical Bisacridine Derivatives Noncovalently Attached to Quaternary Quantum Dots Improve Cancer Therapy by Enhancing Cytotoxicity toward Cancer Cells and Protecting Normal Cells

(2020) Joanna Pilch et al.   ACS Applied Materials & Interfaces

Design, synthesis and high antitumor potential of new unsymmetrical bisacridine derivatives towards human solid tumors, specifically pancreatic cancers and their unique ability to stabilize DNA G-quadruplexes

(2020) Ewa Paluszkiewicz et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

In Vitro Study of the Enzymatic and Nonenzymatic Conjugation of Treosulfan with Glutathione

(2019) Michał Romański et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

Glutathione Transferase P1-1 an Enzyme Useful in Biomedicine and as Biomarker in Clinical Practice and in Environmental Pollution

(2019) Alessio Bocedi et al.   Nutrients

N-Acetylcysteine as an antioxidant and disulphide breaking agent: the reasons why

(2018) Giancarlo Aldini et al.   FREE RADICAL RESEARCH

Glutathione transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases

(2018) Nerino Allocati et al.   Oncogenesis

Drug metabolism in drug discovery and development

(2018) Zhoupeng Zhang et al.   Acta Pharmaceutica Sinica B

Expression of CYP and GST in human normal and colon tumor tissues

(2018) H Bulus et al.   BIOTECHNIC & HISTOCHEMISTRY

Glutathione S-Transferases and Cytochrome P450 enzyme expression in patients with Intracranial Tumors: Preliminary Report of 55 Patients

(2018) Cahit Kural et al.   MEDICAL PRINCIPLES AND PRACTICE

Simulation of interindividual differences in inactivation of reactive para -benzoquinone imine metabolites of diclofenac by glutathione S -transferases in human liver cytosol

(2016) Michiel W. den Braver et al.   TOXICOLOGY LETTERS

Site of Reactivity Models Predict Molecular Reactivity of Diverse Chemicals with Glutathione

(2015) Tyler B. Hughes et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Nucleophilic substitution of nitro group in nitrotriazolotriazines as a model of potential interaction with cysteine-containing proteins

(2015) Vladimir L. Rusinov et al.   Chemistry of Heterocyclic Compounds

The widespread role of non-enzymatic reactions in cellular metabolism

(2015) Markus A Keller et al.   CURRENT OPINION IN BIOTECHNOLOGY

Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes

(2012) Marcel Deponte   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Glutathione transferases: a structural perspective

(2011) Aaron Oakley   DRUG METABOLISM REVIEWS

Glutathione S-transferases: an overview in cancer research

(2010) Giuliano Di Pietro et al.   Expert Opinion on Drug Metabolism & Toxicology

Structure-based design of anticancer prodrug PABA/NO

(2010) Xinhua Ji   Drug Design Development and Therapy