NAC and Vitamin D Restore CNS Glutathione in Endotoxin-Sensitized Neonatal Hypoxic-Ischemic Rats

Short-term effects of early initiation of magnesium infusion combined with cooling after hypoxia–ischemia in term piglets

(2019) Ingran Lingam et al.   PEDIATRIC RESEARCH

Acute LPS sensitization and continuous infusion exacerbates hypoxic brain injury in a piglet model of neonatal encephalopathy

(2019) Kathryn A. Martinello et al.   Scientific Reports

N-Acetylcysteine rapidly replenishes central nervous system glutathione measured via magnetic resonance spectroscopy in human neonates with hypoxic-ischemic encephalopathy

(2018) Hunter G Moss et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Effect of hypothermia on interleukin-1 receptor antagonist pharmacodynamics in inflammatory-sensitized hypoxic-ischemic encephalopathy of term newborns

(2018) Mathilde Chevin et al.   Journal of Neuroinflammation

Melatonin as an adjunct to therapeutic hypothermia in a piglet model of neonatal encephalopathy: A translational study

(2018) Nicola J. Robertson et al.   NEUROBIOLOGY OF DISEASE

Vitamin D improves functional outcomes in neonatal hypoxic ischemic male rats treated with N -acetylcysteine and hypothermia

(2017) Danielle W. Lowe et al.   NEUROPHARMACOLOGY

Vitamin D insufficiency in neonatal hypoxic–ischemic encephalopathy

(2017) Danielle W Lowe et al.   PEDIATRIC RESEARCH

Phase I randomized clinical trial of N-acetylcysteine in combination with an adjuvant probenecid for treatment of severe traumatic brain injury in children

(2017) Robert S. B. Clark et al.   PLoS One

Neuroprotective effects of hypothermia in inflammatory-sensitized hypoxic-ischemic encephalopathy

(2016) Mathilde Chevin et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Probenecid and N-Acetylcysteine Prevent Loss of Intracellular Glutathione and Inhibit Neuronal Death after Mechanical Stretch Injury In Vitro

(2016) Lina Du et al.   JOURNAL OF NEUROTRAUMA

Association between Admission Serum 25-Hydroxyvitamin D Levels and Functional Outcome of Thrombolyzed Stroke Patients

(2016) Anaïs Daumas et al.   Journal of Stroke & Cerebrovascular Diseases

Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial

(2016) Denis Azzopardi et al.   LANCET NEUROLOGY

Sex-specific effects of N-acetylcysteine in neonatal rats treated with hypothermia after severe hypoxia-ischemia

(2016) Xingju Nie et al.   NEUROSCIENCE RESEARCH

Association between Admission Serum 25-Hydroxyvitamin D Levels and Functional Outcome of Thrombolyzed Stroke Patients

(2016) Anaïs Daumas et al.   Journal of Stroke & Cerebrovascular Diseases

Antenatal endotoxin disrupts lung vitamin D receptor and 25-hydroxyvitamin D 1α-hydroxylase expression in the developing rat

(2015) Erica Mandell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Brain Glutathione Levels – A Novel Biomarker for Mild Cognitive Impairment and Alzheimer’s Disease

(2015) Pravat K. Mandal et al.   BIOLOGICAL PSYCHIATRY

Magnetic resonance imaging-based cerebral tissue classification reveals distinct spatiotemporal patterns of changes after stroke in non-human primates

(2015) Mark. J. R. J. Bouts et al.   BMC NEUROSCIENCE

Serum Vitamin D Status as a Predictor of Prognosis in Patients with Acute Ischemic Stroke

(2015) Kwang-Yeol Park et al.   CEREBROVASCULAR DISEASES

Hypothermia Does Not Reverse Cellular Responses Caused by Lipopolysaccharide in Neonatal Hypoxic-Ischaemic Brain Injury

(2015) Damjan Osredkar et al.   DEVELOPMENTAL NEUROSCIENCE

Status of vitamin D, antioxidant enzymes, and antioxidant substances in neonates with neonatal hypoxic-ischemic encephalopathy

(2015) Mehmet Mutlu et al.   Journal of Maternal-Fetal & Neonatal Medicine

Low Serum Vitamin D Is Independently Associated with Larger Lesion Volumes after Ischemic Stroke

(2015) Anya Turetsky et al.   Journal of Stroke & Cerebrovascular Diseases

N-acetylaspartate Decrease in Acute Stage of Ischemic Stroke:A Perspective from Experimental and Clinical Studies

(2015) Hironaka IGARASHI et al.   Magnetic Resonance in Medical Sciences

Low Serum Vitamin D Is Independently Associated with Larger Lesion Volumes after Ischemic Stroke

(2015) Anya Turetsky et al.   Journal of Stroke & Cerebrovascular Diseases

Vitamin D as a Neurosteroid Affecting the Developing and Adult Brain

(2014) Natalie J. Groves et al.   Annual Review of Nutrition

Effect of vitamin D3 intake on the onset of disease in a murine model of human Krabbe disease

(2014) Manjeet K. Paintlia et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Antenatal Pharmacokinetics and Placental Transfer of N-Acetylcysteine in Chorioamnionitis for Fetal Neuroprotection

(2014) Donald B. Wiest et al.   JOURNAL OF PEDIATRICS

In vivo longitudinal proton magnetic resonance spectroscopy on neonatal hypoxic-ischemic rat brain injury: Neuroprotective effects of acetyl-L-carnitine

(2014) Su Xu et al.   MAGNETIC RESONANCE IN MEDICINE

Metabolic properties in stroked rats revealed by relaxation-enhanced magnetic resonance spectroscopy at ultrahigh fields

(2014) Noam Shemesh et al.   Nature Communications

Vitamin D upregulates glutamate cysteine ligase and glutathione reductase, and GSH formation, and decreases ROS and MCP-1 and IL-8 secretion in high-glucose exposed U937 monocytes

(2013) Sushil K. Jain et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glutathione and γ-glutamylcysteine in the antioxidant and survival functions of mitochondria

(2013) Ruben Quintana-Cabrera et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Neuroprotective effect of calcitriol on ischemic/reperfusion injury through the NR3A/CREB pathways in the rat hippocampus

(2013) JUN FU et al.   Molecular Medicine Reports

Hypothermia is not neuroprotective after infection-sensitized neonatal hypoxic–ischemic brain injury

(2013) Damjan Osredkar et al.   RESUSCITATION

Interference with RhoA–ROCK Signaling Mechanism in Autoreactive CD4+ T Cells Enhances the Bioavailability of 1,25-Dihydroxyvitamin D3 in Experimental Autoimmune Encephalomyelitis

(2012) Ajaib S. Paintlia et al.   AMERICAN JOURNAL OF PATHOLOGY

Vitamin D Deficiency Exacerbates Experimental Stroke Injury and Dysregulates Ischemia-Induced Inflammation in Adult Rats

(2012) Robyn Balden et al.   ENDOCRINOLOGY

Effects of combination therapy using hypothermia and erythropoietin in a rat model of neonatal hypoxia–ischemia

(2012) Annie Y. Fang et al.   PEDIATRIC RESEARCH

Elevation of glutathione as a therapeutic strategy in Alzheimer disease

(2011) Chava B. Pocernich et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Placental pathology in asphyxiated newborns meeting the criteria for therapeutic hypothermia

(2010) Pia Wintermark et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Mitochondrial Glutathione, a Key Survival Antioxidant

(2009) Montserrat Marí et al.   ANTIOXIDANTS & REDOX SIGNALING

Apoptosis and glutathione: beyond an antioxidant

(2009) R Franco et al.   CELL DEATH AND DIFFERENTIATION

Measurement of glutathione in normal volunteers and stroke patients at 3T using J-difference spectroscopy with minimized subtraction errors

(2009) Li An et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

MR spectroscopic imaging of glutathione in the white and gray matter at 7 T with an application to multiple sclerosis

(2009) Radhika Srinivasan et al.   MAGNETIC RESONANCE IMAGING

Neuroprotection by co-treatment and post-treating with calcitriol following the ischemic and excitotoxic insult in vivo and in vitro

(2009) Małgorzata Kajta et al.   NEUROCHEMISTRY INTERNATIONAL

Vitamin D, a neuro-immunomodulator: Implications for neurodegenerative and autoimmune diseases

(2009) D.A. Fernandes de Abreu et al.   PSYCHONEUROENDOCRINOLOGY

Starving Neurons Show Sex Difference in Autophagy

(2008) Lina Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of glutathione synthesis

(2008) Shelly C. Lu   MOLECULAR ASPECTS OF MEDICINE

Impact of indolent inflammation on neonatal hypoxic-ischemic brain injury in mice

(2007) John D.E. Barks et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE