Progress in Stereoselective Construction of C–C Bonds Enabled by Aldolases and Hydroxynitrile Lyases

CH‐π Interactions Promote the Conversion of Hydroxypyruvate in a Class II Pyruvate Aldolase

(2019) Stefan R. Marsden et al.   ADVANCED SYNTHESIS & CATALYSIS

Improving and Inverting Cβ-Stereoselectivity of Threonine Aldolase via Substrate-Binding-Guided Mutagenesis and a Stepwise Visual Screening

(2019) Qijia Chen et al.   ACS Catalysis

Building Up Quaternary Stereocenters Through Biocatalyzed Direct Insertion of Carbon Nucleophiles on Ketones

(2019) Nicoletta Gaggero   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Identification and application of threonine aldolase for synthesis of valuable α-amino, β-hydroxy-building blocks

(2019) Mathieu Ligibel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Application of Threonine Aldolases for the Asymmetric Synthesis of α-Quaternary α-Amino Acids

(2018) Julia Blesl et al.   ChemCatChem

Progress in using threonine aldolases for preparative synthesis

(2018) Sarah F. Beaudoin et al.   ENZYME AND MICROBIAL TECHNOLOGY

2-Deoxy-d-ribose-5-phosphate aldolase (DERA): applications and modifications

(2018) Meera Haridas et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The crystal structure and catalytic mechanism of hydroxynitrile lyase from passion fruit, Passiflora edulis

(2017) Fumihiro Motojima et al.   FEBS Journal

Reconstitution and Substrate Specificity of the Radical S-Adenosyl-methionine Thiazole C-Methyltransferase in Thiomuracin Biosynthesis

(2017) Nilkamal Mahanta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineering of d-fructose-6-phosphate aldolase A for improved activity towards cinnamaldehyde

(2017) Xiaohong Yang et al.   Catalysis Science & Technology

Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily

(2017) Elisa Lanfranchi et al.   Scientific Reports

An Enantio- and Diastereoselective Chemoenzymatic Synthesis of α-Fluoro β-Hydroxy Carboxylic Esters

(2016) James K. Howard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Minimalist Protein Engineering of an Aldolase Provokes Unprecedented Substrate Promiscuity

(2016) Deniz Güclü et al.   ACS Catalysis

Asymmetric assembly of aldose carbohydrates from formaldehyde and glycolaldehyde by tandem biocatalytic aldol reactions

(2015) Anna Szekrenyi et al.   Nature Chemistry

Discovery and molecular and biocatalytic properties of hydroxynitrile lyase from an invasive millipede,Chamberlinius hualienensis

(2015) Mohammad Dadashipour et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydroxynitrile Lyase-Catalyzed Synthesis of Enantiopure Cyanohydrins in Biocatalytic Active Static Emulsions (BASE) with Suppression of the Non-Enzymatic Side Reaction

(2014) Jan von Langermann et al.   ADVANCED SYNTHESIS & CATALYSIS

Improving the Properties of BacterialR-Selective Hydroxynitrile Lyases for Industrial Applications

(2014) Romana Wiedner et al.   ChemCatChem

Engineering the Donor Selectivity ofD-Fructose-6-Phosphate Aldolase for Biocatalytic Asymmetric Cross-Aldol Additions of Glycolaldehyde

(2014) Anna Szekrenyi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Engineering aldolases as biocatalysts

(2014) Claire L Windle et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Discovery of a novel (R)-selective bacterial hydroxynitrile lyase from Acidobacterium capsulatum

(2014) Romana Wiedner et al.   Computational and Structural Biotechnology Journal

Biocatalytic Methods for CC Bond Formation

(2013) Kateryna Fesko et al.   ChemCatChem

DHAP-dependent aldolases from (hyper)thermophiles: biochemistry and applications

(2013) Pierpaolo Falcicchio et al.   EXTREMOPHILES

Biochemical and structural characterization of a novel bacterial manganese-dependent hydroxynitrile lyase

(2013) Ivan Hajnal et al.   FEBS Journal

Glycopeptide antibiotic biosynthesis

(2013) Grace Yim et al.   JOURNAL OF ANTIBIOTICS

Biocatalytic Approaches to the Henry (Nitroaldol) Reaction

(2012) Sinéad E. Milner et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Current Trends in Asymmetric Synthesis with Aldolases

(2011) Pere Clapés et al.   ADVANCED SYNTHESIS & CATALYSIS

Structure-guided redesign of d-fructose-6-phosphate aldolase from E. coli: remarkable activity and selectivity towards acceptor substrates by two-point mutation

(2011) Mariana Gutierrez et al.   CHEMICAL COMMUNICATIONS

S-selective hydroxynitrile lyase from a plant Baliospermum montanum: Molecular characterization of recombinant enzyme

(2011) Mohammad Dadashipour et al.   JOURNAL OF BIOTECHNOLOGY

A study towards efficient l-threonine aldolase-catalyzed enantio- and diastereoselective aldol reactions of glycine with substituted benzaldehydes: biocatalyst production and process development

(2011) Katrin Baer et al.   TETRAHEDRON-ASYMMETRY

A Mutant D-Fructose-6-Phosphate Aldolase (Ala129Ser) with Improved Affinity towards Dihydroxyacetone for the Synthesis of Polyhydroxylated Compounds

(2010) José A. Castillo et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Retro-Henry Reaction Catalyzed by Hydroxynitrile Lyase from Hevea brasiliensis

(2010) Ruslan Yuryev et al.   ChemCatChem

Recent progress in stereoselective synthesis with aldolases

(2010) Pere Clapés et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Hydroxynitrile lyase from Passiflora edulis: Purification, characteristics and application in asymmetric synthesis of (R)-mandelonitrile

(2010) Techawaree Ueatrongchit et al.   ENZYME AND MICROBIAL TECHNOLOGY

Biocatalytic Access to α,α-Dialkyl-α-amino Acids by a Mechanism-Based Approach

(2009) Kateryna Fesko et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Practical Heterogeneous Catalyst for the Suzuki, Sonogashira, and Stille Coupling Reactions of Unreactive Aryl Chlorides

(2009) Myung-Jong Jin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A green-by-design biocatalytic process for atorvastatin intermediate

(2009) Steven K. Ma et al.   GREEN CHEMISTRY