ARHGEF18/p114RhoGEF Coordinates PKA/CREB Signaling and Actomyosin Remodeling to Promote Trophoblast Cell-Cell Fusion During Placenta Morphogenesis

Interplay between Extracellular Matrix Stiffness and JAM-A Regulates Mechanical Load on ZO-1 and Tight Junction Assembly

(2020) Alexis J. Haas et al.   Cell Reports

The mechanobiology of actin cytoskeletal proteins during cell–cell fusion

(2019) Jing Cong et al.   Journal of the Royal Society Interface

Placentation defects are highly prevalent in embryonic lethal mouse mutants

(2018) Vicente Perez-Garcia et al.   NATURE

A Mechanosensitive RhoA Pathway that Protects Epithelia against Acute Tensile Stress

(2018) Bipul R. Acharya et al.   DEVELOPMENTAL CELL

Association between a Single Nucleotide Polymorphism in the 3′-UTR of ARHGEF18 and the Risk of Nonidiopathic Pulmonary Arterial Hypertension in Chinese Population

(2018) Ding Li et al.   DISEASE MARKERS

An apical MRCK-driven morphogenetic pathway controls epithelial polarity

(2017) Ceniz Zihni et al.   NATURE CELL BIOLOGY

Efficient Induction of Syncytiotrophoblast Layer II Cells from Trophoblast Stem Cells by Canonical Wnt Signaling Activation

(2017) Dongmei Zhu et al.   Stem Cell Reports

The basal chorionic trophoblast cell layer: An emerging coordinator of placenta development

(2016) Katharina Walentin et al.   BIOESSAYS

Plet1 is an epigenetically regulated cell surface protein that provides essential cues to direct trophoblast stem cell differentiation

(2016) Alexander Murray et al.   Scientific Reports

Mechanical Tension Drives Cell Membrane Fusion

(2015) Ji Hoon Kim et al.   DEVELOPMENTAL CELL

Shear wave elastography of placenta: in vivo quantitation of placental elasticity in preeclampsia

(2015) Fahrettin Kilic et al.   Diagnostic and Interventional Radiology

Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks

(2015) Paulina A. Latos et al.   GENES & DEVELOPMENT

ZO-1 controls endothelial adherens junctions, cell–cell tension, angiogenesis, and barrier formation

(2015) Olga Tornavaca et al.   JOURNAL OF CELL BIOLOGY

Review: An overview of molecular events occurring in human trophoblast fusion

(2015) P. Gerbaud et al.   PLACENTA

Shear wave elastography of placenta: in vivo quantitation of placental elasticity in preeclampsia

(2015) Fahrettin Kilic et al.   Diagnostic and Interventional Radiology

MarvelD3 couples tight junctions to the MEKK1–JNK pathway to regulate cell behavior and survival

(2014) Emily Steed et al.   JOURNAL OF CELL BIOLOGY

A PKA-ezrin-Cx43 signaling complex controls gap junction communication and thereby trophoblast cell fusion

(2014) G. Pidoux et al.   JOURNAL OF CELL SCIENCE

PKA Compartmentalization via AKAP220 and AKAP12 Contributes to Endothelial Barrier Regulation

(2014) Mariya Y. Radeva et al.   PLoS One

ArhGEF18 regulates RhoA-Rock2 signaling to maintain neuro-epithelial apico-basal polarity and proliferation

(2013) Cathrin Herder et al.   DEVELOPMENT

Keratin 5-Cre-driven excision of nonmuscle myosin IIA in early embryo trophectoderm leads to placenta defects and embryonic lethality

(2013) James Crish et al.   DEVELOPMENTAL BIOLOGY

LKB1 Controls Human Bronchial Epithelial Morphogenesis through p114RhoGEF-Dependent RhoA Activation

(2013) X. Xu et al.   MOLECULAR AND CELLULAR BIOLOGY

The Molecular Role of Connexin 43 in Human Trophoblast Cell Fusion1

(2012) Caroline E. Dunk et al.   BIOLOGY OF REPRODUCTION

Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex

(2012) Ahmed Elbediwy et al.   JOURNAL OF CELL BIOLOGY

DLC1 Interaction with  -Catenin Stabilizes Adherens Junctions and Enhances DLC1 Antioncogenic Activity

(2012) V. Tripathi et al.   MOLECULAR AND CELLULAR BIOLOGY

Stimulation of Cortical Myosin Phosphorylation by p114RhoGEF Drives Cell Migration and Tumor Cell Invasion

(2012) Stephen J. Terry et al.   PLoS One

Rho GTP exchange factor ARHGEF11 regulates the integrity of epithelial junctions by connecting ZO-1 and RhoA-Myosin II signaling

(2012) M. Itoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lulu2 regulates the circumferential actomyosin tensile system in epithelial cells through p114RhoGEF

(2011) Hiroyuki Nakajima et al.   JOURNAL OF CELL BIOLOGY

Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis

(2011) Stephen J. Terry et al.   NATURE CELL BIOLOGY

Interplay of cAMP and MAPK pathways in hCG secretion and fusogenic gene expression in a trophoblast cell line

(2010) M. Delidaki et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Rho Signaling and Tight Junction Functions

(2010) Steve Terry et al.   PHYSIOLOGY

Loss of the ssecks/gravin/akap12 Gene Results in Prostatic Hyperplasia

(2008) S. Akakura et al.   CANCER RESEARCH