Fidgetin-like 2 negatively regulates axonal growth and can be targeted to promote functional nerve regeneration

A Novel Therapeutic Approach to Corneal Alkaline Burn Model by Targeting Fidgetin-Like 2, a Microtubule Regulator

(2021) Jessie Wang et al.   Translational Vision Science & Technology

A comparative study of the expression patterns of Fign family members in zebrafish embryonic development

(2020) Zhangji Dong et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Knockdown of fidgetin improves regeneration of injured axons by a microtubule-based mechanism

(2019) Andrew J. Matamoros et al.   JOURNAL OF NEUROSCIENCE

The model of local axon homeostasis - explaining the role and regulation of microtubule bundles in axon maintenance and pathology

(2019) Ines Hahn et al.   Neural Development

Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex

(2019) Yue Qu et al.   eLife

Cytoskeleton dynamics in axon regeneration

(2018) Oriane Blanquie et al.   CURRENT OPINION IN NEUROBIOLOGY

Systemic epothilone D improves hindlimb function after spinal cord contusion injury in rats

(2018) Beatrice Sandner et al.   EXPERIMENTAL NEUROLOGY

Systemic administration of epothilone D improves functional recovery of walking after rat spinal cord contusion injury

(2018) Jörg Ruschel et al.   EXPERIMENTAL NEUROLOGY

Motor axon navigation relies on Fidgetin-like 1–driven microtubule plus end dynamics

(2018) Coralie Fassier et al.   JOURNAL OF CELL BIOLOGY

Microtubule-severing enzymes: From cellular functions to molecular mechanism

(2018) Francis J. McNally et al.   JOURNAL OF CELL BIOLOGY

Fidgetin-Like 2 siRNA Enhances the Wound Healing Capability of a Surfactant Polymer Dressing

(2018) Brian P. O'Rourke et al.   Advances in Wound Care

Fidgetin regulates cultured astrocyte migration by severing tyrosinated microtubules at the leading edge

(2017) Zunlu Hu et al.   MOLECULAR BIOLOGY OF THE CELL

The effect of cavernous nerve traction on erectile function in rats

(2017) Hao Li et al.   PLoS One

Nanoparticle Delivery of Fidgetin siRNA as a Microtubule-based Therapy to Augment Nerve Regeneration

(2017) Timothy O. Austin et al.   Scientific Reports

Stability properties of neuronal microtubules

(2016) Peter W. Baas et al.   Cytoskeleton

Cut Your Losses: Spastin Mediates Branch-Specific Axon Loss

(2016) Hagar Meltzer et al.   NEURON

Stripe Assay to Study the Attractive or Repulsive Activity of a Protein Substrate Using Dissociated Hippocampal Neurons

(2016) Satoru Yamagishi et al.   Jove-Journal of Visualized Experiments

Potential Role of Semaphorin 3A and Its Receptors in Regulating Aberrant Sympathetic Innervation in Peritoneal and Deep Infiltrating Endometriosis

(2016) Yanchun Liang et al.   PLoS One

Caspase-3 dependent nitrergic neuronal apoptosis following cavernous nerve injury is mediated via RhoA and ROCK activation in major pelvic ganglion

(2016) Johanna L. Hannan et al.   Scientific Reports

Role of macrophages in Wallerian degeneration and axonal regeneration after peripheral nerve injury

(2015) Peiwen Chen et al.   ACTA NEUROPATHOLOGICA

Penile rehabilitation following prostate cancer treatment: review of current literature

(2015) Run Wang et al.   ASIAN JOURNAL OF ANDROLOGY

Fidgetin-Like 2: A Microtubule-Based Regulator of Wound Healing

(2015) Rabab A. Charafeddine et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Inhibition of kinesin-5 improves regeneration of injured axons by a novel microtubule-based mechanism

(2015) PeterW Baas et al.   Neural Regeneration Research

Building the Neuronal Microtubule Cytoskeleton

(2015) Lukas C. Kapitein et al.   NEURON

Systemic administration of epothilone B promotes axon regeneration after spinal cord injury

(2015) J. Ruschel et al.   SCIENCE

Vertebrate Fidgetin Restrains Axonal Growth by Severing Labile Domains of Microtubules

(2015) Lanfranco Leo et al.   Cell Reports

The tubulin code: Molecular components, readout mechanisms, and functions

(2014) Carsten Janke   JOURNAL OF CELL BIOLOGY

Beyond taxol: microtubule-based treatment of disease and injury of the nervous system

(2013) Peter W. Baas et al.   BRAIN

CFEOM1-Associated Kinesin KIF21A Is a Cortical Microtubule Growth Inhibitor

(2013) Babet van der Vaart et al.   DEVELOPMENTAL CELL

Transglutaminase and Polyamination of Tubulin: Posttranslational Modification for Stabilizing Axonal Microtubules

(2013) Yuyu Song et al.   NEURON

Whole genome microarray of the major pelvic ganglion after cavernous nerve injury: new insights into molecular profile changes after nerve injury

(2012) Giulia Calenda et al.   BJU INTERNATIONAL

Microtubule deacetylation sets the stage for successful axon regeneration

(2012) Li Chen et al.   EMBO JOURNAL

HDAC5 is a novel injury-regulated tubulin deacetylase controlling axon regeneration

(2012) Yongcheol Cho et al.   EMBO JOURNAL

Microtubule-severing enzymes at the cutting edge

(2012) D. J. Sharp et al.   JOURNAL OF CELL SCIENCE

Genetic Study of Axon Regeneration with Cultured Adult Dorsal Root Ganglion Neurons

(2012) Saijilafu et al.   Jove-Journal of Visualized Experiments

Taxol Facilitates Axon Regeneration in the Mature CNS

(2011) V. Sengottuvel et al.   JOURNAL OF NEUROSCIENCE

Semaphorin 3A inhibits growth of adult sympathetic and parasympathetic neurones via distinct cyclic nucleotide signalling pathways

(2010) MR Nangle et al.   BRITISH JOURNAL OF PHARMACOLOGY

EphB Signaling Directs Peripheral Nerve Regeneration through Sox2-Dependent Schwann Cell Sorting

(2010) Simona Parrinello et al.   CELL

Tubulin polyglutamylation stimulates spastin-mediated microtubule severing

(2010) Benjamin Lacroix et al.   JOURNAL OF CELL BIOLOGY

Acetylation of Microtubules Influences Their Sensitivity to Severing by Katanin in Neurons and Fibroblasts

(2010) H. Sudo et al.   JOURNAL OF NEUROSCIENCE

Microtubule-severing enzymes

(2009) Antonina Roll-Mecak et al.   CURRENT OPINION IN CELL BIOLOGY

The trip of the tip: understanding the growth cone machinery

(2009) Laura Anne Lowery et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Erectile dysfunction following prostatectomy: prevention and treatment

(2009) Ahmed Magheli et al.   Nature Reviews Urology

The Microtubule-severing Proteins Spastin and Katanin Participate Differently in the Formation of Axonal Branches

(2008) Wenqian Yu et al.   MOLECULAR BIOLOGY OF THE CELL

Cavernous nerve regeneration using acellular nerve grafts

(2008) Stephen S. Connolly et al.   WORLD JOURNAL OF UROLOGY