Targeting ACLY Attenuates Tumor Growth and Acquired Cisplatin Resistance in Ovarian Cancer by Inhibiting the PI3K–AKT Pathway and Activating the AMPK–ROS Pathway

Cancer statistics, 2019

(2019) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Functional Diversity of p53 in Human and Wild Animals

(2019) Yi Li et al.   Frontiers in Endocrinology

Low expression of ACLY associates with favorable prognosis in acute myeloid leukemia

(2019) Jinghan Wang et al.   Journal of Translational Medicine

Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle

(2019) Koen H. G. Verschueren et al.   NATURE

NCCN Guidelines Insights: Ovarian Cancer, Version 1.2019

(2019) Deborah K. Armstrong et al.   Journal of the National Comprehensive Cancer Network

Overexpression of ATP citrate lyase in renal cell carcinoma tissues and its effect on the human renal carcinoma cells in�vitro

(2018) Lichen Teng et al.   Oncology Letters

Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism

(2016) Supriya Shah et al.   Oncotarget

ATP Citrate Lyase (ACLY): A Promising Target for Cancer Prevention and Treatment

(2015) Amrita Khwairakpam et al.   CURRENT DRUG TARGETS

Anti-diabetic Drug Metformin: Challenges and Perspectives for Cancer Therapy

(2014) Kaniyampadi Snima et al.   CURRENT CANCER DRUG TARGETS

ATP-citrate lyase regulates cellular senescence via an AMPK- and p53-dependent pathway

(2014) Jong-Hyuk Lee et al.   FEBS Journal

Ovarian cancer

(2014) Gordon C Jayson et al.   LANCET

Inhibition of ATP Citrate Lyase Induces an Anticancer Effect via Reactive Oxygen Species

(2013) Toshiro Migita et al.   AMERICAN JOURNAL OF PATHOLOGY

Pathview: an R/Bioconductor package for pathway-based data integration and visualization

(2013) Weijun Luo et al.   BIOINFORMATICS

Inhibition of ATP citrate lyase induces triglyceride accumulation with altered fatty acid composition in cancer cells

(2013) Toshiro Migita et al.   INTERNATIONAL JOURNAL OF CANCER

ATP Citrate Lyase Mediates Resistance of Colorectal Cancer Cells to SN38

(2013) Y. Zhou et al.   MOLECULAR CANCER THERAPEUTICS

Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth

(2013) Ruiting Lin et al.   MOLECULAR CELL

A global view of the biochemical pathways involved in the regulation of the metabolism of cancer cells

(2012) Philippe Icard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Prognostic and therapeutic implications of increased ATP citrate lyase expression in human epithelial ovarian cancer

(2012) YU WANG et al.   ONCOLOGY REPORTS

Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen-activated protein Kinase (MAPK) and Phosphatidylinositol-3-kinase (PI3K)/AKT pathways

(2011) Jun-ichi Hanai et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A Glucose-to-Gene Link

(2009) J. C. Rathmell et al.   SCIENCE

ATP Citrate Lyase: Activation and Therapeutic Implications in Non-Small Cell Lung Cancer

(2008) T. Migita et al.   CANCER RESEARCH