Substrate Stiffness and Stretch Regulate Profibrotic Mechanosignaling in Pulmonary Arterial Adventitial Fibroblasts

Quantification of uncertainty in a new network model of pulmonary arterial adventitial fibroblast pro-fibrotic signalling

(2020) Ariel Wang et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Quantification of model and data uncertainty in a network analysis of cardiac myocyte mechanosignalling

(2020) Shulin Cao et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Role of Extracellular Matrix in the Pathogenesis of Pulmonary Arterial Hypertension

(2018) Thenappan Thenappan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Factors Associated with Heritable Pulmonary Arterial Hypertension Exert Convergent Actions on the miR-130/301-Vascular Matrix Feedback Loop

(2018) Thomas Bertero et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanobiological Feedback in Pulmonary Vascular Disease

(2018) Paul B. Dieffenbach et al.   Frontiers in Physiology

Mechanical regulation of cardiac fibroblast profibrotic phenotypes

(2017) Kate M. Herum et al.   MOLECULAR BIOLOGY OF THE CELL

Predictive model identifies key network regulators of cardiomyocyte mechano-signaling

(2017) Philip M. Tan et al.   PLoS Computational Biology

Stretch-induced Activation of Transforming Growth Factor-β1in Pulmonary Fibrosis

(2016) Aaron R. Froese et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A computational model of cardiac fibroblast signaling predicts context-dependent drivers of myofibroblast differentiation

(2016) A.C. Zeigler et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Role of TRP channels in the cardiovascular system

(2015) Zhichao Yue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit

(2015) Thomas Bertero et al.   Cell Reports

Danshensu Inhibits β-Adrenergic Receptors-Mediated Cardiac Fibrosis by ROS/p38 MAPK Axis

(2014) Haiyan Lu et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

JNK suppresses pulmonary fibroblast elastogenesis during alveolar development

(2014) Sheng Liu et al.   RESPIRATORY RESEARCH

Inflammation and Mechanical Stretch Promote Aortic Stiffening in Hypertension Through Activation of p38 Mitogen-Activated Protein Kinase

(2013) Jing Wu et al.   CIRCULATION RESEARCH

Osteopontin is an endogenous modulator of the constitutively activated phenotype of pulmonary adventitial fibroblasts in hypoxic pulmonary hypertension

(2012) Adil Anwar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress

(2012) Kate M. Herum et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Formation of composite polyacrylamide and silicone substrates for independent control of stiffness and strain

(2012) Chelsey S. Simmons et al.   LAB ON A CHIP

Interstitial fluid flow and cyclic strain differentially regulate cardiac fibroblast activation via AT1R and TGF-β1

(2011) P.A. Galie et al.   EXPERIMENTAL CELL RESEARCH

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

The renin-angiotensin system mediates hyperoxia-induced collagen production in human lung fibroblasts

(2010) Yaw-Dong Lang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Thrombin-Induced Connective Tissue Growth Factor Expression in Human Lung Fibroblasts Requires the ASK1/JNK/AP-1 Pathway

(2009) C.-C. Yu et al.   JOURNAL OF IMMUNOLOGY

The PDE1A-PKCα Signaling Pathway Is Involved in the Upregulation of α-Smooth Muscle Actin by TGF-β1 in Adventitial Fibroblasts

(2009) Hai-Yan Zhou et al.   JOURNAL OF VASCULAR RESEARCH