Lumican Inhibits In Vivo Melanoma Metastasis by Altering Matrix-Effectors and Invadopodia Markers

Label-Free Infrared Spectral Histology of Skin Tissue Part I: Impact of Lumican on Extracellular Matrix Integrity

(2020) Lise Nannan et al.   Frontiers in Cell and Developmental Biology

Advances in cyclin-dependent kinase inhibitors for the treatment of melanoma

(2020) Maximilian Julve et al.   EXPERT OPINION ON PHARMACOTHERAPY

Progress report on the major clinical advances in patient-oriented research into familial melanoma (2013–2018)

(2019) Mijke Visser et al.   Familial Cancer

UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression

(2019) James M. Arnold et al.   ONCOGENE

The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges

(2019) Loh et al.   Cells

Lumican as a multivalent effector in wound healing

(2018) Konstantina Karamanou et al.   ADVANCED DRUG DELIVERY REVIEWS

Tumor-suppressive functions of 4-MU on breast cancer cells of different ER status: Regulation of hyaluronan/HAS2/CD44 and specific matrix effectors

(2018) Theodoros T. Karalis et al.   MATRIX BIOLOGY

Proteoglycan Chemical Diversity Drives Multifunctional Cell Regulation and Therapeutics

(2018) Nikos K. Karamanos et al.   CHEMICAL REVIEWS

Melanoma

(2018) Dirk Schadendorf et al.   LANCET

The close relationship between heparanase and epithelial mesenchymal transition in gastric signet-ring cell adenocarcinoma

(2018) Shahid Shah et al.   Oncotarget

Cortactin and fascin-1 regulate extracellular vesicle release by controlling endosomal trafficking or invadopodia formation and function

(2018) Els Beghein et al.   Scientific Reports

Inhibition of heparanase protects against chronic kidney dysfunction following ischemia/reperfusion injury

(2018) Valentina Masola et al.   Oncotarget

Small leucine-rich proteoglycans and matrix metalloproteinase-14: Key partners?

(2017) Katarzyna Pietraszek-Gremplewicz et al.   MATRIX BIOLOGY

Cell matrix adhesions in cancer: The proteins that form the glue

(2017) Mazvita Maziveyi et al.   Oncotarget

Lumican delays melanoma growth in mice and drives tumor molecular assembly as well as response to matrix-targeted TAX2 therapeutic peptide

(2017) Albin Jeanne et al.   Scientific Reports

Lumican effectively regulates the estrogen receptors-associated functional properties of breast cancer cells, expression of matrix effectors and epithelial-to-mesenchymal transition

(2017) Konstantina Karamanou et al.   Scientific Reports

Lumican Inhibits SNAIL-Induced Melanoma Cell Migration Specifically by Blocking MMP-14 Activity

(2016) Marta Stasiak et al.   PLoS One

Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells

(2015) Panagiotis Bouris et al.   MATRIX BIOLOGY

Snail and Slug collaborate on EMT and tumor metastasis through miR-101-mediated EZH2 axis in oral tongue squamous cell carcinoma

(2015) Min Zheng et al.   Oncotarget

The Role of Snail in EMT and Tumorigenesis

(2014) Yifan Wang et al.   CURRENT CANCER DRUG TARGETS

Lumican: A new inhibitor of matrix metalloproteinase-14 activity

(2014) Katarzyna Pietraszek et al.   FEBS LETTERS

Lumican effects in the control of tumour progression and their links with metalloproteinases and integrins

(2013) Stéphane Brézillon et al.   FEBS Journal

Oncogene abnormalities in a series of primary melanomas of the sinonasal tract: NRAS mutations and cyclin D1 amplification are more frequent than KIT or BRAF mutations

(2013) Meriem Chraybi et al.   HUMAN PATHOLOGY

Lumican affects tumor cell functions, tumor–ECM interactions, angiogenesis and inflammatory response

(2013) Dragana Nikitovic et al.   MATRIX BIOLOGY

Lumican – Derived Peptides Inhibit Melanoma Cell Growth and Migration

(2013) Katarzyna Pietraszek et al.   PLoS One

Cortactin in cell migration and cancer at a glance

(2012) S. M. MacGrath et al.   JOURNAL OF CELL SCIENCE

Hyaluronan Synthase 2 (HAS2) Promotes Breast Cancer Cell Invasion by Suppression of Tissue Metalloproteinase Inhibitor 1 (TIMP-1)

(2011) Berit Bernert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lumican inhibits cell migration through α2β1 integrin

(2010) Cédric Zeltz et al.   EXPERIMENTAL CELL RESEARCH

Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis

(2010) Uri Barash et al.   FEBS Journal

SRC-3Δ4 Mediates the Interaction of EGFR with FAK to Promote Cell Migration

(2010) Weiwen Long et al.   MOLECULAR CELL

FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion

(2009) Keefe T. Chan et al.   JOURNAL OF CELL BIOLOGY

A new role for cortactin in invadopodia: Regulation of protease secretion

(2008) E CLARK et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

MMP-14 mediated MMP-9 expression is involved in TGF-beta1-induced keratinocyte migration

(2008) Young Seomun et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes

(2008) Juha Hakulinen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY