Lumican effects in the control of tumour progression and their links with metalloproteinases and integrins

Secreted 70kDa lumican stimulates growth and inhibits invasion of human pancreatic cancer

(2012) Tetsushi Yamamoto et al.   CANCER LETTERS

Insights into Targeting Colon Cancer Cell Fate at the Level of Proteoglycans / Glycosaminoglycans

(2012) D. Nikitovic et al.   CURRENT MEDICINAL CHEMISTRY

Overexpression of lumican affects the migration of human colon cancer cells through up-regulation of gelsolin and filamentous actin reorganization

(2012) Agata Radwanska et al.   EXPERIMENTAL CELL RESEARCH

Glycosaminoglycans: key players in cancer cell biology and treatment

(2012) Nikos Afratis et al.   FEBS Journal

The Biology of Small Leucine-rich Proteoglycans in Bone Pathophysiology

(2012) Dragana Nikitovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteoglycans in prostate cancer

(2012) Iris J. Edwards   Nature Reviews Urology

Effect of Lumican on the Migration of Human Mesenchymal Stem Cells and Endothelial Progenitor Cells: Involvement of Matrix Metalloproteinase-14

(2012) Mariusz Malinowski et al.   PLoS One

MT1-MMP Cleavage of the Antiangiogenic Proteoglycan Decorin: Role in Corneal Angiogenesis

(2011) Tatsuya Mimura et al.   CORNEA

Lumican regulates osteosarcoma cell adhesion by modulating TGFβ2 activity

(2011) Dragana Nikitovic et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Lumican inhibits angiogenesis by interfering with α2β1 receptor activity and downregulating MMP-14 expression

(2011) Jolanta Niewiarowska et al.   THROMBOSIS RESEARCH

Enhanced expression of lumican inhibited the attachment and growth of human embryonic kidney 293 cells

(2010) Toshiyuki Ishiwata et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Fibroblast and prostate tumor cell cross-talk: Fibroblast differentiation, TGF-β, and extracellular matrix down-regulation

(2010) Vivien J. Coulson-Thomas et al.   EXPERIMENTAL CELL RESEARCH

Lumican inhibits cell migration through α2β1 integrin

(2010) Cédric Zeltz et al.   EXPERIMENTAL CELL RESEARCH

Proteoglycans in cancer biology, tumour microenvironment and angiogenesis

(2010) Renato V. Iozzo et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Lumican core protein inhibits melanoma cell migration via alterations of focal adhesion complexes

(2009) Stéphane Brézillon et al.   CANCER LETTERS

Lumcorin: A leucine-rich repeat 9-derived peptide from human lumican inhibiting melanoma cell migration

(2009) Cédric Zeltz et al.   FEBS LETTERS

Extracellular Matrix Lumican Deposited on the Surface of Neutrophils Promotes Migration by Binding to β2Integrin

(2009) Seakwoo Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Accelerated arterial stiffening and gene expression profile of the aorta in patients with coronary artery disease

(2009) Céline Fassot et al.   JOURNAL OF HYPERTENSION

Metabolism of proteoglycans in tendon

(2009) S. G. Rees et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Lumican induces human corneal epithelial cell migration and integrin expression via ERK 1/2 signaling

(2008) Young Seomun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tumor microenvironment: Modulation by decorin and related molecules harboring leucine-rich tandem motifs

(2008) Silvia Goldoni et al.   INTERNATIONAL JOURNAL OF CANCER

Lumican, a small leucine-rich proteoglycan

(2008) Dragana Nikitovic et al.   IUBMB LIFE

Homologous Sequence in Lumican and Fibromodulin Leucine-rich Repeat 5-7 Competes for Collagen Binding

(2008) Sebastian Kalamajski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biological Functions of the Small Leucine-rich Proteoglycans: From Genetics to Signal Transduction

(2008) Liliana Schaefer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lumican affects actin cytoskeletal organization in human melanoma A375 cells

(2008) Agata Radwanska et al.   LIFE SCIENCES

Identification of β1 integrin as mediator of melanoma cell adhesion to lumican

(2007) Marie-France D’Onofrio et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS