TNFAIP8 Regulates Intestinal Epithelial Cell Differentiation and May Alter Terminal Differentiation of Secretory Progenitors

TNFAIP8 controls murine intestinal stem cell homeostasis and regeneration by regulating microbiome-induced Akt signaling

(2020) Jason R. Goldsmith et al.   Nature Communications

Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity

(2019) Jing Liu et al.   DEVELOPMENTAL CELL

Profiling of chromatin accessibility and identification of general cis-regulatory mechanisms that control two ocular lens differentiation pathways

(2019) Yilin Zhao et al.   Epigenetics & Chromatin

Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types

(2018) Benjamin E. Mead et al.   BMC BIOLOGY

Increased expression of GATA zinc finger domain containing 1 through gene amplification promotes liver cancer by directly inducing phosphatase of regenerating liver 3

(2018) Wei Sun et al.   HEPATOLOGY

Tales from the crypt: intestinal niche signals in tissue renewal, plasticity and cancer

(2018) Maureen Spit et al.   Open Biology

Sox4 Promotes Atoh1-Independent Intestinal Secretory Differentiation Toward Tuft and Enteroendocrine Fates

(2018) Adam D. Gracz et al.   GASTROENTEROLOGY

Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis

(2018) Patricia Santofimia-Castaño et al.   Scientific Reports

A single-cell survey of the small intestinal epithelium

(2017) Adam L. Haber et al.   NATURE

Single-cell mRNA quantification and differential analysis with Census

(2017) Xiaojie Qiu et al.   NATURE METHODS

Reversed graph embedding resolves complex single-cell trajectories

(2017) Xiaojie Qiu et al.   NATURE METHODS

Intrinsically disordered chromatin protein NUPR1 binds to the C-terminal region of Polycomb RING1B

(2017) Patricia Santofimia-Castaño et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of adult intestinal identity by the Polycomb repressive machinery

(2016) Fulvio Chiacchiera et al.   CELL CYCLE

8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors

(2016) Vassilios Bavetsias et al.   JOURNAL OF MEDICINAL CHEMISTRY

Molecular insights into the binding of phosphoinositides to the TH domain region of TIPE proteins

(2016) Priya Antony et al.   JOURNAL OF MOLECULAR MODELING

Crucial Roles of TNFAIP8 Protein in Regulating Apoptosis andListeriaInfection

(2015) Thomas P. Porturas et al.   JOURNAL OF IMMUNOLOGY

Histone Demethylases KDM4A and KDM4C Regulate Differentiation of Embryonic Stem Cells to Endothelial Cells

(2015) Liangtang Wu et al.   Stem Cell Reports

TIPE3 Is the Transfer Protein of Lipid Second Messengers that Promote Cancer

(2014) Svetlana A. Fayngerts et al.   CANCER CELL

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

GPS2/KDM4A Pioneering Activity Regulates Promoter-Specific Recruitment of PPARγ

(2014) M. Dafne Cardamone et al.   Cell Reports

Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis

(2012) Tewfik Hamidi et al.   JOURNAL OF CLINICAL INVESTIGATION

Homozygosity Mapping and Exome Sequencing Reveal GATAD1 Mutation in Autosomal Recessive Dilated Cardiomyopathy

(2011) Jeanne L. Theis et al.   Circulation-Cardiovascular Genetics

Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells

(2011) K. L. VanDussen et al.   DEVELOPMENT

Origin of the brush cell lineage in the mouse intestinal epithelium

(2011) Matthew Bjerknes et al.   DEVELOPMENTAL BIOLOGY

Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium

(2011) François Gerbe et al.   JOURNAL OF CELL BIOLOGY

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

(2011) Wim de Lau et al.   NATURE

A New Isoform of the Histone Demethylase JMJD2A/KDM4A Is Required for Skeletal Muscle Differentiation

(2011) Laure Verrier et al.   PLoS Genetics

Mouse atonal homolog 1 directs intestinal progenitors to secretory cell rather than absorptive cell fate

(2010) Kelli L. VanDussen et al.   DEVELOPMENTAL BIOLOGY

Altered intestinal epithelial homeostasis in mice with intestine-specific deletion of the Krüppel-like factor 4 gene

(2010) Amr M. Ghaleb et al.   DEVELOPMENTAL BIOLOGY

SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells

(2009) Taeko K. Noah et al.   EXPERIMENTAL CELL RESEARCH

TIPE2, a Negative Regulator of Innate and Adaptive Immunity that Maintains Immune Homeostasis

(2008) Honghong Sun et al.   CELL

A Different TIPE of Immune Homeostasis

(2008) Eric C. Freundt et al.   CELL

Current View: Intestinal Stem Cells and Signaling

(2008) David H. Scoville et al.   GASTROENTEROLOGY

Crystal structure of TIPE2 provides insights into immune homeostasis

(2008) Xu Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY