Atypical E2Fs either Counteract or Cooperate with RB during Tumorigenesis Depending on Tissue Context

E2F7 is a potent inhibitor of liver tumor growth in adult mice

(2020) Eva Moreno et al.   HEPATOLOGY

Excessive E2F Transcription in Single Cancer Cells Precludes Transient Cell-Cycle Exit after DNA Damage

(2020) Hendrika A. Segeren et al.   Cell Reports

Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation

(2019) Maria C. Cuitiño et al.   Cell Reports

Cyclin F‐dependent degradation of E2F7 is critical for DNA repair and G2‐phase progression

(2019) Ruixue Yuan et al.   EMBO JOURNAL

Chk1 and 14‐3‐3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest

(2018) Ruixue Yuan et al.   EMBO JOURNAL

Feedback regulation between atypical E2Fs and APC/CCdh1coordinates cell cycle progression

(2016) Michiel Boekhout et al.   EMBO REPORTS

RB localizes to DNA double-strand breaks and promotes DNA end resection and homologous recombination through the recruitment of BRG1

(2016) Renier Vélez-Cruz et al.   GENES & DEVELOPMENT

E2f8 mediates tumor suppression in postnatal liver development

(2016) Lindsey N. Kent et al.   JOURNAL OF CLINICAL INVESTIGATION

Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer

(2016) I Thurlings et al.   ONCOGENE

E2F8 as a Novel Therapeutic Target for Lung Cancer

(2015) Sin-Aye Park et al.   JNCI-Journal of the National Cancer Institute

E2F8 as a Novel Therapeutic Target for Lung Cancer

(2015) Sin-Aye Park et al.   JNCI-Journal of the National Cancer Institute

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Control of cell cycle transcription during G1 and S phases

(2013) Cosetta Bertoli et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Atypical E2F Repressors and Activators Coordinate Placental Development

(2012) Madhu M. Ouseph et al.   DEVELOPMENTAL CELL

E2F7, a novel target, is up-regulated by p53 and mediates DNA damage-dependent transcriptional repression

(2012) L. A. Carvajal et al.   GENES & DEVELOPMENT

The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence

(2012) O. Aksoy et al.   GENES & DEVELOPMENT

E2F8 is essential for polyploidization in mammalian cells

(2012) Shusil K. Pandit et al.   NATURE CELL BIOLOGY

RB deletion disrupts coordination between DNA replication licensing and mitotic entry in vivo

(2011) Ryan J. Bourgo et al.   MOLECULAR BIOLOGY OF THE CELL

E2F7 represses a network of oscillating cell cycle genes to control S-phase progression

(2011) Bart Westendorp et al.   NUCLEIC ACIDS RESEARCH

Synergistic Function of E2F7 and E2F8 Is Essential for Cell Survival and Embryonic Development

(2008) Jing Li et al.   DEVELOPMENTAL CELL

A Genetic Screen for Increased Loss of Heterozygosity in Saccharomyces cerevisiae

(2008) M. P. Andersen et al.   GENETICS