Desmoglein-4 Deficiency Exacerbates Psoriasiform Dermatitis in Rats While Psoriasis Patients Displayed a Decreased Gene Expression of DSG4

Non-invasive delivery of biological macromolecular drugs into the skin by iontophoresis and its application to psoriasis treatment

(2020) Tatsuya Fukuta et al.   JOURNAL OF CONTROLLED RELEASE

Atopic dermatitis is an IL-13 dominant disease with greater molecular heterogeneity compared to psoriasis

(2019) Lam C. Tsoi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

LC-MS/MS analyses of open flow microperfusion samples quantify eicosanoids in a rat model of skin inflammation

(2019) Cornelia Pipper et al.   JOURNAL OF LIPID RESEARCH

Comparison of dendritic cells obtained from autoimmunty-prone and resistant rats

(2019) Neda Djedovic et al.   IMMUNOBIOLOGY

Post-transcriptional regulation of inflammation by RNA-binding proteins via cis-elements of mRNAs

(2019) Yutaro Uchida et al.   JOURNAL OF BIOCHEMISTRY

Targeting the IL-17 receptor using liposomal spherical nucleic acids as topical therapy for psoriasis

(2019) Haoming Liu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Resident and monocyte-derived Langerhans cells are required for imiquimod-induced psoriasis-like dermatitis model

(2018) Minseok Lee et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Decreased expression of IL-27 in moderate-to-severe psoriasis and its anti-inflammation role in imiquimod-induced psoriasis-like mouse model

(2017) Wenjuan Chen et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Impact of T-cell-specific Smad4 deficiency on the development of autoimmune diabetes in NOD mice

(2016) Donghee Kim et al.   IMMUNOLOGY AND CELL BIOLOGY

Strain-Related Differences in the Immune Response: Relevance to Human Stroke

(2016) Kyra J. Becker   Translational Stroke Research

An Autosomal Recessive Mutation of DSG4 Causes Monilethrix through the ER Stress Response

(2015) Madoka Kato et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Epidermal Th22 and Tc17 Cells Form a Localized Disease Memory in Clinically Healed Psoriasis

(2014) S. Cheuk et al.   JOURNAL OF IMMUNOLOGY

Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation

(2013) Robert M. Harmon et al.   JOURNAL OF CLINICAL INVESTIGATION

Roles of TLR7 in Activation of NF-κB Signaling of Keratinocytes by Imiquimod

(2013) Zheng Jun Li et al.   PLoS One

Desmoglein 3 acting as an upstream regulator of Rho GTPases, Rac-1/Cdc42 in the regulation of actin organisation and dynamics

(2012) Siu Man Tsang et al.   EXPERIMENTAL CELL RESEARCH

Increased MAPK and NF-κB expression of Langerhans cells is dependent on TLR2 and TLR4, and increased IRF-3 expression is partially dependent on TLR4 following UV exposure

(2011) Zhigang Bi   Molecular Medicine Reports

Major role for mRNA stability in shaping the kinetics of gene induction

(2010) Ran Elkon et al.   BMC GENOMICS

Downregulation of SMAD2, 4 and 6 mRNA and TGFβ Receptor I mRNA in Lesional and Non-lesional Psoriatic Skin

(2009) H Yu et al.   ACTA DERMATO-VENEREOLOGICA

Desmoglein 4 is regulated by transcription factors implicated in hair shaft differentiation

(2009) Hisham Bazzi et al.   DIFFERENTIATION

Molecular Dissection of Psoriasis: Integrating Genetics and Biology

(2009) James T. Elder et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Desmosome

(2009) E. Delva et al.   Cold Spring Harbor Perspectives in Biology

Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity

(2008) Philip Owens et al.   DEVELOPMENTAL BIOLOGY