- Home
- Publications
- Publication Search
- Publication Details
Title
Low-Dose IL-2 Therapy in Autoimmune and Rheumatic Diseases
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-04-01
DOI
10.3389/fimmu.2021.648408
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Autoimmunity and organ damage in systemic lupus erythematosus
- (2020) George C. Tsokos NATURE IMMUNOLOGY
- Low-dose IL-2 in children with recently diagnosed type 1 diabetes: a Phase I/II randomised, double-blind, placebo-controlled, dose-finding study
- (2020) Michelle Rosenzwajg et al. DIABETOLOGIA
- Repeated 5-day cycles of low dose aldesleukin in amyotrophic lateral sclerosis (IMODALS): A phase 2a randomised, double-blind, placebo-controlled trial
- (2020) William Camu et al. EBioMedicine
- Phenotyping of Adaptive Immune Responses in Inflammatory Diseases
- (2020) Jens Y. Humrich et al. Frontiers in Immunology
- Interleukin-2 Deficiency Associated with Renal Impairment in Systemic Lupus Erythematosus
- (2019) Miao Shao et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Dysregulation of T Follicular Helper Cells in Lupus
- (2019) John D. Mountz et al. JOURNAL OF IMMUNOLOGY
- Efficacy and safety of low-dose IL-2 in the treatment of systemic lupus erythematosus: a randomised, double-blind, placebo-controlled trial
- (2019) Jing He et al. ANNALS OF THE RHEUMATIC DISEASES
- Low dose of IL-2 combined with rapamycin restores and maintains the long-term balance of Th17/Treg cells in refractory SLE patients
- (2019) Chunmiao Zhao et al. BMC IMMUNOLOGY
- Circulating regulatory T cells were absolutely decreased in dermatomyositis/polymyositis patients and restored by low-dose IL-2
- (2019) Sheng-Xiao Zhang et al. ANNALS OF THE RHEUMATIC DISEASES
- Mechanisms of action of low-dose IL-2 restoration therapies in SLE
- (2019) André Ballesteros-Tato et al. CURRENT OPINION IN IMMUNOLOGY
- Short-term and low-dose IL-2 therapy restores the Th17/Treg balance in the peripheral blood of patients with primary Sjögren’s syndrome
- (2018) Miao Miao et al. ANNALS OF THE RHEUMATIC DISEASES
- Low Dose Interleukin-2 for Refractory Autoimmune Hepatitis
- (2018) Tiong Y. Lim et al. HEPATOLOGY
- Targeting Regulatory T Cells to Treat Patients With Systemic Lupus Erythematosus
- (2018) Masayuki Mizui et al. Frontiers in Immunology
- Immunological and clinical effects of low-dose interleukin-2 across 11 autoimmune diseases in a single, open clinical trial
- (2018) Michelle Rosenzwajg et al. ANNALS OF THE RHEUMATIC DISEASES
- Low-dose interleukin-2 therapy for the treatment of systemic lupus erythematosus
- (2018) Jens Y. Humrich et al. CURRENT OPINION IN RHEUMATOLOGY
- Regulatory T cells in the treatment of disease
- (2018) Amir Sharabi et al. NATURE REVIEWS DRUG DISCOVERY
- Restoring regulation – IL-2 therapy in systemic lupus erythematosus
- (2016) Jens Y. Humrich et al. Expert Review of Clinical Immunology
- Low-dose interleukin-2 treatment selectively modulates CD4+ T cell subsets in patients with systemic lupus erythematosus
- (2016) Jing He et al. NATURE MEDICINE
- The rise of IL-2 therapy — a novel biologic treatment for SLE
- (2016) Jens Y. Humrich et al. Nature Reviews Rheumatology
- New insights into the immunopathogenesis of systemic lupus erythematosus
- (2016) George C. Tsokos et al. Nature Reviews Rheumatology
- Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial
- (2016) John A. Todd et al. PLOS MEDICINE
- Low-Dose IL-2 in the Treatment of Lupus
- (2016) Masayuki Mizui et al. Current Rheumatology Reports
- Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus
- (2015) Caroline von Spee-Mayer et al. ANNALS OF THE RHEUMATIC DISEASES
- Rapid induction of clinical remission by low-dose interleukin-2 in a patient with refractory SLE
- (2015) Jens Y Humrich et al. ANNALS OF THE RHEUMATIC DISEASES
- Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients
- (2015) Michelle Rosenzwajg et al. JOURNAL OF AUTOIMMUNITY
- Regulatory T cells in systemic lupus erythematosus
- (2014) Kim Ohl et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Beyond regulatory T cells: the potential role for IL-2 to deplete T-follicular helper cells and treat autoimmune diseases
- (2014) André Ballesteros-Tato Immunotherapy
- Phenotypic and Functional Analysis of CD4+CD25-Foxp3+ T Cells in Patients with Systemic Lupus Erythematosus
- (2014) M. Bonelli et al. JOURNAL OF IMMUNOLOGY
- TREG-cell therapies for autoimmune rheumatic diseases
- (2014) Makoto Miyara et al. Nature Reviews Rheumatology
- Effects of Low-Dose Recombinant Interleukin 2 to Promote T-Regulatory Cells in Alopecia Areata
- (2014) Emeline Castela et al. JAMA Dermatology
- Circulating Precursor CCR7loPD-1hi CXCR5+ CD4+ T Cells Indicate Tfh Cell Activity and Promote Antibody Responses upon Antigen Reexposure
- (2013) Jing He et al. IMMUNITY
- Low-dose interleukin 2 in patients with type 1 diabetes: a phase 1/2 randomised, double-blind, placebo-controlled trial
- (2013) Agnès Hartemann et al. Lancet Diabetes & Endocrinology
- Rapamycin/IL-2 Combination Therapy in Patients With Type 1 Diabetes Augments Tregs yet Transiently Impairs -Cell Function
- (2012) S. A. Long et al. DIABETES
- Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survival
- (2012) Jenny S. Henkel et al. EMBO Molecular Medicine
- Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation
- (2012) André Ballesteros-Tato et al. IMMUNITY
- Rapamycin Causes Upregulation of Autophagy and Impairs Islets Function Both In Vitro and In Vivo
- (2011) M. Tanemura et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Human FoxP3+ regulatory T cells in systemic autoimmune diseases
- (2011) Makoto Miyara et al. AUTOIMMUNITY REVIEWS
- Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity
- (2011) Shi-Bing Yang et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Systemic Lupus Erythematosus
- (2011) George C. Tsokos NEW ENGLAND JOURNAL OF MEDICINE
- Regulatory T-Cell Responses to Low-Dose Interleukin-2 in HCV-Induced Vasculitis
- (2011) David Saadoun et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interleukin-2 and Regulatory T Cells in Graft-versus-Host Disease
- (2011) John Koreth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interleukin-2 Receptor Signaling: At the Interface between Tolerance and Immunity
- (2010) Thomas R. Malek et al. IMMUNITY
- IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells
- (2010) Yenkel Grinberg-Bleyer et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Rapamycin Prevents and Breaks the Anti-CD3-Induced Tolerance in NOD Mice
- (2009) A. Valle et al. DIABETES
- Regulatory T cells exert checks and balances on self tolerance and autoimmunity
- (2009) Kajsa Wing et al. NATURE IMMUNOLOGY
- Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus
- (2009) J. Y. Humrich et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Central Role of Defective Interleukin-2 Production in the Triggering of Islet Autoimmune Destruction
- (2008) Qizhi Tang et al. IMMUNITY
- The Biology of Interleukin-2
- (2007) Thomas R. Malek Annual Review of Immunology
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now