Pulmonary Procoagulant and Innate Immune Responses in Critically Ill COVID-19 Patients

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Role of Platelet-Derived Growth Factor (PDGF) in Asthma as an Immunoregulatory Factor Mediating Airway Remodeling and Possible Pharmacological Target

(2020) Grzegorz Kardas et al.   Frontiers in Pharmacology

COVID-19 Does Not Lead to a “Typical” Acute Respiratory Distress Syndrome

(2020) Luciano Gattinoni et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

COVID-19 and its implications for thrombosis and anticoagulation

(2020) Jean Marie Connors et al.   BLOOD

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

The Innate Immune System: Fighting on the Front Lines or Fanning the Flames of COVID-19?

(2020) Julia L. McKechnie et al.   Cell Host & Microbe

Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients

(2020) Zhuo Zhou et al.   Cell Host & Microbe

Complement activation in patients with COVID-19: A novel therapeutic target

(2020) Massimo Cugno et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clinical and immunological features of severe and moderate coronavirus disease 2019

(2020) Guang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

(2020) Mingfeng Liao et al.   NATURE MEDICINE

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

(2020) Maximilian Ackermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pharmacological Agents Targeting Thromboinflammation in COVID-19: Review and Implications for Future Research

(2020) Mahesh V. Madhavan et al.   THROMBOSIS AND HAEMOSTASIS

Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases

(2020) Cynthia Magro et al.   Translational Research

Characterization of the Inflammatory Response to Severe COVID-19 Illness

(2020) Oliver J McElvaney et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19)

(2020) W. Joost Wiersinga et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

COVID-19: Complement, Coagulation, and Collateral Damage

(2020) Martin W. Lo et al.   JOURNAL OF IMMUNOLOGY

Cytokine storm and leukocyte changes in mild versus severe SARS‐CoV‐2 infection: Review of 3939 COVID‐19 patients in China and emerging pathogenesis and therapy concepts

(2020) Jin Wang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Coagulopathy in COVID‐19

(2020) Toshiaki Iba et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series

(2020) Benjamin T Bradley et al.   LANCET

Association of COVID-19 inflammation with activation of the C5a–C5aR1 axis

(2020) Julien Carvelli et al.   NATURE

Impaired Breakdown of Bradykinin and Its Metabolites as a Possible Cause for Pulmonary Edema in COVID-19 Infection

(2020) Steven de Maat et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies

(2020) Yujun Tang et al.   Frontiers in Immunology

Anticipating and managing coagulopathy and thrombotic manifestations of severe COVID-19

(2020) Lucas C. Godoy et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Cytokine Levels in Critically Ill Patients With COVID-19 and Other Conditions

(2020) Matthijs Kox et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Tackling the cytokine storm in COVID-19, challenges and hopes

(2020) Shifaa M. Abdin et al.   LIFE SCIENCES

Is COVID-19 associated thrombosis caused by overactivation of the complement cascade? A literature review

(2020) Alexander Fletcher-Sandersjöö et al.   THROMBOSIS RESEARCH

Acute respiratory distress syndrome

(2019) Michael A. Matthay et al.   Nature Reviews Disease Primers

Classical dendritic cells regulate acute lung inflammation and injury in mice with lipopolysaccharide‑induced acute respiratory distress syndrome

(2019) Lang Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

ACE2 Antagonizes VEGFa to Reduce Vascular Permeability During Acute Lung Injury

(2016) Xiaobo Yu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation

(2016) Kristina N. Ekdahl et al.   IMMUNOLOGICAL REVIEWS

Contact system revisited: an interface between inflammation, coagulation, and innate immunity

(2016) A. T. Long et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Immunothrombosis in Acute Respiratory Distress Syndrome: Cross Talks between Inflammation and Coagulation

(2016) Frantzeska Frantzeskaki et al.   RESPIRATION

Platelet Activation: The Mechanisms and Potential Biomarkers

(2016) Seong-Hoon Yun et al.   Biomed Research International

Vascular Endothelial Growth Factor in Acute Lung Injury and Acute Respiratory Distress Syndrome

(2013) S. Barratt et al.   RESPIRATION

FMS-Like Tyrosine Kinase 3 Ligand Treatment of Mice Aggravates Acute Lung Injury in Response to Streptococcus pneumoniae: Role of Pneumolysin

(2012) Christina Brumshagen et al.   INFECTION AND IMMUNITY

Acute Respiratory Distress Syndrome

(2012)   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Bronchoalveolar hemostasis in lung injury and acute respiratory distress syndrome

(2012) G. J. GLAS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Advances in assay of complement function and activation

(2011) Morten Harboe et al.   ADVANCED DRUG DELIVERY REVIEWS

Mannose-Binding Lectin (MBL) Substitution: Recovery of Opsonic Function In Vivo Lags behind MBL Serum Levels

(2009) N. Brouwer et al.   JOURNAL OF IMMUNOLOGY