Subunit Vaccines Using TLR Triagonist Combination Adjuvants Provide Protection Against Coxiella burnetii While Minimizing Reactogenic Responses

The Use of Toll-Like Receptor Agonists in HIV-1 Cure Strategies

(2020) Janne Tegder Martinsen et al.   Frontiers in Immunology

A Novel Synthetic Dual Agonistic Liposomal TLR4/7 Adjuvant Promotes Broad Immune Responses in an Influenza Vaccine With Minimal Reactogenicity

(2020) Fumi Sato-Kaneko et al.   Frontiers in Immunology

Seroprevalence of Q fever among high-risk occupations in the Ilam province, the west of Iran

(2019) Ehsan Mostafavi et al.   PLoS One

Serological evidence of Coxiella burnetii infection in cattle and farm workers: is Q fever an underreported zoonotic disease in Ecuador?

(2019) Gustavo Echeverría et al.   Infection and Drug Resistance

Linked Toll-Like Receptor Triagonists Stimulate Distinct, Combination-Dependent Innate Immune Responses

(2019) Tyler J. Albin et al.   ACS Central Science

A Coxiella burnetii intratracheal aerosol infection model in mice, guinea pigs and non-human primates

(2019) A. E. Gregory et al.   INFECTION AND IMMUNITY

Coxiella burnetii seroprevalence in unvaccinated veterinary workers in Australia: Evidence to support Q fever vaccination

(2019) Emily Sellens et al.   Zoonoses and Public Health

Tuning Subunit Vaccines with Novel TLR Triagonist Adjuvants to Generate Protective Immune Responses against Coxiella burnetii

(2019) Adrienne P. Gilkes et al.   JOURNAL OF IMMUNOLOGY

Immunomodulation of the NLRP3 Inflammasome through Structure-Based Activator Design and Functional Regulation via Lysosomal Rupture

(2018) Saikat Manna et al.   ACS Central Science

The TLR-4 agonist adjuvant, GLA-SE, improves magnitude and quality of immune responses elicited by the ID93 tuberculosis vaccine: first-in-human trial

(2018) Rhea N. Coler et al.   npj Vaccines

Standardized guinea pig model for Q fever vaccine reactogenicity

(2018) Laurie A. Baeten et al.   PLoS One

Applications of Immunomodulatory Immune Synergies to Adjuvant Discovery and Vaccine Development

(2018) Janine K. Tom et al.   TRENDS IN BIOTECHNOLOGY

Synthetic Toll-Like Receptor 4 (TLR4) and TLR7 Ligands Work Additively via MyD88 To Induce Protective Antiviral Immunity in Mice

(2017) Peter H. Goff et al.   JOURNAL OF VIROLOGY

Combinatorial Delivery of Dual and Triple TLR Agonists via Polymeric Pathogen-like Particles Synergistically Enhances Innate and Adaptive Immune Responses

(2017) Ranjna Madan-Lala et al.   Scientific Reports

Toll-Like Receptor 2 (TLR2) and TLR9 Play Opposing Roles in Host Innate Immunity against Salmonella enterica Serovar Typhimurium Infection

(2015) Renhui Zhan et al.   INFECTION AND IMMUNITY

Confocal Imaging–Guided Laser Ablation of Basal Cell Carcinomas: An Ex Vivo Study

(2015) Heidy Sierra et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity

(2015) Geoffrey M Lynn et al.   NATURE BIOTECHNOLOGY

Recent Advances of Vaccine Adjuvants for Infectious Diseases

(2015) Sujin Lee et al.   Immune Network

Central Role of MyD88-Dependent Dendritic Cell Maturation and Proinflammatory Cytokine Production to Control Brucella abortus Infection

(2014) G. C. Macedo et al.   JOURNAL OF IMMUNOLOGY

TLR4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A Differentially Regulate Effector and Memory CD8+ T Cell Differentiation

(2014) W. Cui et al.   JOURNAL OF IMMUNOLOGY

Vaccination against Q fever for biodefense and public health indications

(2014) Sara Ruiz et al.   Frontiers in Microbiology

Formalin-Inactivated Coxiella burnetii Phase I Vaccine-Induced Protection Depends on B Cells To Produce Protective IgM and IgG

(2013) Guoquan Zhang et al.   INFECTION AND IMMUNITY

Identification of Substituted Pyrimido[5,4-b]indoles as Selective Toll-Like Receptor 4 Ligands

(2013) Michael Chan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Multifunctional Dendronized Peptide Polymer Platform for Safe and Effective siRNA Delivery

(2013) Hanxiang Zeng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular pathogenesis of the obligate intracellular bacterium Coxiella burnetii

(2013) Erin J. van Schaik et al.   NATURE REVIEWS MICROBIOLOGY

Q fever and pregnancy: disease, prevention, and strain specificity

(2012) E. Angelakis et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Isolation from Animal Tissue and Genetic Transformation of Coxiella burnetii Are Facilitated by an Improved Axenic Growth Medium

(2011) Anders Omsland et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

TLR4 Signaling via MyD88 and TRIF Differentially Shape the CD4+ T Cell Response to Porphyromonas gingivalis Hemagglutinin B

(2011) D. E. Gaddis et al.   JOURNAL OF IMMUNOLOGY

Profiling the Humoral Immune Response of Acute and Chronic Q Fever by Protein Microarray

(2011) Adam Vigil et al.   MOLECULAR & CELLULAR PROTEOMICS

Toll-like Receptor 2 Signaling in CD4+ T Lymphocytes Promotes T Helper 17 Responses and Regulates the Pathogenesis of Autoimmune Disease

(2010) Joseph M. Reynolds et al.   IMMUNITY

Role of CD4+ and CD8+ T Cells in Clearance of Primary Pulmonary Infection with Coxiella burnetii

(2010) A. J. Read et al.   INFECTION AND IMMUNITY

Q Fever Pneumonia

(2010) Thomas J. Marrie   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Mice Deficient in MyD88 Develop a Th2-Dominant Response and Severe Pathology in the Upper Genital Tract following Chlamydia muridarum Infection

(2010) Lili Chen et al.   JOURNAL OF IMMUNOLOGY

Genome-wide profiling of humoral immune response to Coxiella burnetii infection by protein microarray

(2010) Adam Vigil et al.   PROTEOMICS

TLR-based immune adjuvants

(2010) Folkert Steinhagen et al.   VACCINE

Dendrimers for Vaccine and Immunostimulatory Uses. A Review

(2009) Peter M. H. Heegaard et al.   BIOCONJUGATE CHEMISTRY

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS