Nicotinamide Mononucleotide Attenuates Renal Interstitial Fibrosis After AKI by Suppressing Tubular DNA Damage and Senescence

Cyclin G1 and TASCC regulate kidney epithelial cell G2-M arrest and fibrotic maladaptive repair

(2019) Guillaume Canaud et al.   Science Translational Medicine

Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3-dependent mechanism in male mice

(2019) Nina Klimova et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cryptotanshinone inhibits hypoxia/reoxygenation‐induced oxidative stress and apoptosis in renal tubular epithelial cells

(2019) Rui Zhu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease

(2019) Hisayuki Amano et al.   Cell Metabolism

Nicotinamide reduces renal interstitial fibrosis by suppressing tubular injury and inflammation

(2019) Meiling Zheng et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Nicotinamide riboside, an NAD+ precursor, attenuates the development of liver fibrosis in a diet-induced mouse model of liver fibrosis

(2019) Tho X. Pham et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Proximal tubule ATR regulates DNA repair to prevent maladaptive renal injury responses

(2019) Seiji Kishi et al.   JOURNAL OF CLINICAL INVESTIGATION

A reduced form of nicotinamide riboside defines a new path for NAD+ biosynthesis and acts as an orally bioavailable NAD+ precursor

(2019) Judith Giroud-Gerbetant et al.   Molecular Metabolism

Human DNA ligase IV is able to use NAD+ as an alternative adenylation donor for DNA ends ligation

(2018) Shih-Hsun Chen et al.   NUCLEIC ACIDS RESEARCH

Nicotinamide Mononucleotide, an NAD + Precursor, Rescues Age-Associated Susceptibility to AKI in a Sirtuin 1–Dependent Manner

(2017) Yi Guan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A conserved NAD + binding pocket that regulates protein-protein interactions during aging

(2017) Jun Li et al.   SCIENCE

The Fountain of Youth by Targeting Senescent Cells?

(2017) Peter L.J. de Keizer   TRENDS IN MOLECULAR MEDICINE

Cellular senescence in the aging and diseased kidney

(2017) F. A. Valentijn et al.   Journal of Cell Communication and Signaling

Oxidant Mechanisms in Renal Injury and Disease

(2016) Brian B. Ratliff et al.   ANTIOXIDANTS & REDOX SIGNALING

NAD + Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair

(2016) Evandro Fei Fang et al.   Cell Metabolism

Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice

(2016) Kathryn F. Mills et al.   Cell Metabolism

PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection

(2016) Mei T. Tran et al.   NATURE

DNA damage response in cisplatin-induced nephrotoxicity

(2015) Shiyao Zhu et al.   ARCHIVES OF TOXICOLOGY

Acute kidney injury in China: a cross-sectional survey

(2015) Li Yang et al.   LANCET

Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD

(2015) David A. Ferenbach et al.   Nature Reviews Nephrology

ARTD1 (PARP1) activation and NAD+ in DNA repair and cell death

(2014) Elise Fouquerel et al.   DNA REPAIR

Acute kidney injury—epidemiology, outcomes and economics

(2014) Oleksa Rewa et al.   Nature Reviews Nephrology

The diverse roles and clinical relevance of PARPs in DNA damage repair: Current state of the art

(2012) Mike De Vos et al.   BIOCHEMICAL PHARMACOLOGY

Cellular pathophysiology of ischemic acute kidney injury

(2011) Joseph V. Bonventre et al.   JOURNAL OF CLINICAL INVESTIGATION

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

(2010) Li Yang et al.   NATURE MEDICINE