Mitochondrial CHCHD2: Disease-Associated Mutations, Physiological Functions, and Current Animal Models
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Title
Mitochondrial CHCHD2: Disease-Associated Mutations, Physiological Functions, and Current Animal Models
Authors
Keywords
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Journal
Frontiers in Aging Neuroscience
Volume 13, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-04-22
DOI
10.3389/fnagi.2021.660843
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Note: Only part of the references are listed.- Early death of ALS-linked CHCHD10-R15L transgenic mice with central nervous system, skeletal muscle and cardiac pathology
- (2021) Éanna B. Ryan et al. iScience
- Homeostatic p62 levels and inclusion body formation in CHCHD2 knockout mice
- (2021) Shigeto Sato et al. HUMAN MOLECULAR GENETICS
- Chchd2 regulates mitochondrial morphology by modulating the levels of Opa1
- (2020) Wei Liu et al. CELL DEATH AND DIFFERENTIATION
- Amyloid-Beta Peptides Trigger Aggregation of Alpha-Synuclein In Vitro
- (2020) Janett Köppen et al. MOLECULES
- CHCHD10‐regulated OPA1‐mitofilin complex mediates TDP‐43‐induced mitochondrial phenotypes associated with frontotemporal dementia
- (2020) Tian Liu et al. FASEB JOURNAL
- Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations
- (2020) Yi-Ting Liu et al. HUMAN MOLECULAR GENETICS
- Epigenetics in Lewy Body Diseases: Impact on Gene Expression, Utility as a Biomarker, and Possibilities for Therapy
- (2020) Aintzane Urbizu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- ALS and Parkinson's disease genes CHCHD10 and CHCHD2 modify synaptic transcriptomes in human iPSC-derived motor neurons
- (2020) Sandra Harjuhaahto et al. NEUROBIOLOGY OF DISEASE
- MPTP-induced mouse model of Parkinson’s disease: A promising direction of therapeutic strategies
- (2020) Che Norma Mat Taib et al. Bosnian Journal of Basic Medical Sciences
- Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms
- (2020) Siddhesh Aras et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modulation of Alpha-Synuclein Aggregation by Cytochrome c Binding and Hetero-di-Tyrosine Adduct Formation
- (2019) Sumanta Ghosh et al. ACS Chemical Neuroscience
- Pathogenic alpha-synuclein aggregates preferentially bind to mitochondria and affect cellular respiration
- (2019) Xinhe Wang et al. Acta Neuropathologica Communications
- Twin CHCH Proteins, CHCHD2, and CHCHD10: Key Molecules of Parkinson’s Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia
- (2019) Yuzuru Imai et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- ALS/FTD mutant CHCHD10 mice reveal a tissue-specific toxic gain-of-function and mitochondrial stress response
- (2019) Corey J. Anderson et al. ACTA NEUROPATHOLOGICA
- Mitochondrial defect in muscle precedes neuromuscular junction degeneration and motor neuron death in CHCHD10S59L/+ mouse
- (2019) Emmanuelle C. Genin et al. ACTA NEUROPATHOLOGICA
- Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy
- (2019) Balvindar Singh et al. ACTA NEUROPATHOLOGICA
- Mutations in CHCHD2 cause α-synuclein aggregation
- (2019) Aya Ikeda et al. HUMAN MOLECULAR GENETICS
- Mutation Screening of the CHCHD2 Gene for Alzheimer’s Disease and Frontotemporal Dementia in Chinese Mainland Population
- (2018) Xiang-Qian Che et al. JOURNAL OF ALZHEIMERS DISEASE
- The cellular stress proteins CHCHD10 and MNRR1 (CHCHD2): Partners in mitochondrial and nuclear function and dysfunction
- (2018) Neeraja Purandare et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mutation analysis of CHCHD2 and CHCHD10 in Italian patients with mitochondrial myopathy
- (2018) Elisa Rubino et al. NEUROBIOLOGY OF AGING
- A new CHCHD2 mutation identified in a southern italy patient with multiple system atrophy
- (2018) Giuseppe Nicoletti et al. PARKINSONISM & RELATED DISORDERS
- CHCHD2 mutational screening in Brazilian patients with familial Parkinson’s disease
- (2018) Danielle D. Voigt et al. NEUROBIOLOGY OF AGING
- Generation of induced pluripotent stem cell line (ZZUi007-A) from a 52-year-old patient with a novel CHCHD2 gene mutation in Parkinson’s disease
- (2018) Yanlin Wang et al. Stem Cell Research
- Systematically analyzing rare variants of autosomal-dominant genes for sporadic Parkinson's disease in a Chinese cohort
- (2018) Nannan Yang et al. NEUROBIOLOGY OF AGING
- CHCHD10 is involved in the development of Parkinson's disease caused by CHCHD2 loss-of-function mutation p.T61I
- (2018) Chengyuan Mao et al. NEUROBIOLOGY OF AGING
- Loss of CHCHD10–CHCHD2 complexes required for respiration underlies the pathogenicity of a CHCHD10 mutation in ALS
- (2017) Isabella R Straub et al. HUMAN MOLECULAR GENETICS
- In vitro and in vivo studies of the ALS-FTLD protein CHCHD10 reveal novel mitochondrial topology and protein interactions
- (2017) S R Burstein et al. HUMAN MOLECULAR GENETICS
- Varied pathological and therapeutic response effects associated with CHCHD2 mutant and risk variants
- (2017) Murni Tio et al. HUMAN MUTATION
- Dementia with Lewy bodies and Parkinson’s disease-dementia: current concepts and controversies
- (2017) Kurt A. Jellinger JOURNAL OF NEURAL TRANSMISSION
- Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis
- (2017) David J Irwin et al. LANCET NEUROLOGY
- Selective neuronal vulnerability in Parkinson disease
- (2017) D. James Surmeier et al. NATURE REVIEWS NEUROSCIENCE
- Analysis of CHCHD2 gene in familial Parkinson's disease from Calabria
- (2017) Monica Gagliardi et al. NEUROBIOLOGY OF AGING
- Genetic analysis of CHCHD2 in a southern Spanish population
- (2017) Cristina Tejera-Parrado et al. NEUROBIOLOGY OF AGING
- A novel mutation of CHCHD2 p.R8H in a sporadic case of Parkinson's disease
- (2017) Aya Ikeda et al. PARKINSONISM & RELATED DISORDERS
- Loss of Parkinson’s disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c
- (2017) Hongrui Meng et al. Nature Communications
- Loss of function CHCHD10 mutations in cytoplasmic TDP-43 accumulation and synaptic integrity
- (2017) Jung-A. A. Woo et al. Nature Communications
- Genetic analysis ofCHCHD2gene in Chinese Parkinson's disease
- (2016) Nan-Nan Li et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages
- (2016) Lili Zhu et al. JOURNAL OF CELL BIOLOGY
- Role of cytochrome c in α-synuclein radical formation: implications of α-synuclein in neuronal death in Maneb- and paraquat-induced model of Parkinson’s disease
- (2016) Ashutosh Kumar et al. Molecular Neurodegeneration
- Dementia in Parkinson's disease is associated with enhanced mitochondrial complex I deficiency
- (2016) Ariana P. Gatt et al. MOVEMENT DISORDERS
- Mutation analysis of CHCHD2 in Canadian patients with familial Parkinson's disease
- (2016) Ming Zhang et al. NEUROBIOLOGY OF AGING
- CHCHD2 gene mutations in familial and sporadic Parkinson's disease
- (2016) Chang-he Shi et al. NEUROBIOLOGY OF AGING
- Lack of CHCHD2 mutations in Parkinson's disease in a Taiwanese population
- (2016) Tian-Sin Fan et al. NEUROBIOLOGY OF AGING
- A nonsense mutation inCHCHD2in a patient with Parkinson disease
- (2016) Eva Koschmidder et al. NEUROLOGY
- Genetic analysis of the CHCHD2 gene in a cohort of Chinese patients with Parkinson disease
- (2016) Hongwei Wu et al. NEUROSCIENCE LETTERS
- Mutational scanning of the CHCHD2 gene in Han Chinese patients with Parkinson’s disease and meta-analysis of the literature
- (2016) Xinglong Yang et al. PARKINSONISM & RELATED DISORDERS
- Mutation analysis of the CHCHD2 gene in Chinese Han patients with Parkinson's disease
- (2016) Qian Lu et al. PARKINSONISM & RELATED DISORDERS
- α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson’s disease
- (2016) Roberto Di Maio et al. Science Translational Medicine
- Mitochondrial Proteins Containing Coiled-Coil-Helix-Coiled-Coil-Helix (CHCH) Domains in Health and Disease
- (2016) Nazanine Modjtahedi et al. TRENDS IN BIOCHEMICAL SCIENCES
- High Frequency of GBA Gene Mutations in Dementia With Lewy Bodies Among Ashkenazi Jews
- (2016) Tamara Shiner et al. JAMA Neurology
- Mutation analysis ofCHCHD10in different neurodegenerative diseases
- (2015) Ming Zhang et al. BRAIN
- Balancing mitochondrial biogenesis and mitophagy to maintain energy metabolism homeostasis
- (2015) K Palikaras et al. CELL DEATH AND DIFFERENTIATION
- CHCHD10 mutations promote loss of mitochondrial cristae junctions with impaired mitochondrial genome maintenance and inhibition of apoptosis
- (2015) E. C. Genin et al. EMBO Molecular Medicine
- CHCHD2 and Parkinson's disease
- (2015) Jia Nee Foo et al. LANCET NEUROLOGY
- CHCHD2 and Parkinson's disease
- (2015) Guiyou Liu et al. LANCET NEUROLOGY
- CHCHD2 and Parkinson's disease
- (2015) Iris E Jansen et al. LANCET NEUROLOGY
- CHCHD2 mutations in autosomal dominant late-onset Parkinson's disease: a genome-wide linkage and sequencing study
- (2015) Manabu Funayama et al. LANCET NEUROLOGY
- MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism
- (2015) Siddhesh Aras et al. MITOCHONDRION
- CHCHD2 Is Coamplified with EGFR in NSCLC and Regulates Mitochondrial Function and Cell Migration
- (2015) Y. Wei et al. MOLECULAR CANCER RESEARCH
- Mitochondrial targeting sequence variants of theCHCHD2gene are a risk for Lewy body disorders
- (2015) Kotaro Ogaki et al. NEUROLOGY
- Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease
- (2015) Brent J. Ryan et al. TRENDS IN BIOCHEMICAL SCIENCES
- Two novel mutations in conserved codons indicate that CHCHD10 is a gene associated with motor neuron disease
- (2014) Kathrin Müller et al. BRAIN
- Mutations in the CHCHD10 gene are a common cause of familial amyotrophic lateral sclerosis
- (2014) Janel O. Johnson et al. BRAIN
- A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement
- (2014) Sylvie Bannwarth et al. BRAIN
- CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation
- (2014) Y Liu et al. CELL DEATH AND DIFFERENTIATION
- Mutation in the novel nuclear-encoded mitochondrial protein CHCHD10 in a family with autosomal dominant mitochondrial myopathy
- (2014) Senda Ajroud-Driss et al. NEUROGENETICS
- Lewy body disease and dementia with Lewy bodies
- (2014) Kenji KOSAKA PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- The clinical characteristics of dementia with Lewy bodies and a consideration of prodromal diagnosis
- (2014) Paul C Donaghy et al. Alzheimers Research & Therapy
- Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies
- (2013) David J. Irwin et al. NATURE REVIEWS NEUROSCIENCE
- Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2
- (2013) Siddhesh Aras et al. NUCLEIC ACIDS RESEARCH
- Role of Oxidative Stress in Parkinson's Disease
- (2013) Onyou Hwang Experimental Neurobiology
- Neuropathologic substrates of Parkinson disease dementia
- (2012) David J. Irwin et al. ANNALS OF NEUROLOGY
- Physiological Roles of Mitochondrial Reactive Oxygen Species
- (2012) Laura A. Sena et al. MOLECULAR CELL
- The Lewy Body in Parkinson’s Disease and Related Neurodegenerative Disorders
- (2012) Koichi Wakabayashi et al. MOLECULAR NEUROBIOLOGY
- Living on the edge with too many mouths to feed: Why dopamine neurons die
- (2012) J. Paul Bolam et al. MOVEMENT DISORDERS
- Studies of protein aggregation in A53T α-synuclein transgenic, Tg2576 transgenic, and P246L presenilin-1 knock-in cross bred mice
- (2011) Kristel L. Emmer et al. NEUROSCIENCE LETTERS
- The sites and topology of mitochondrial superoxide production
- (2010) Martin D. Brand EXPERIMENTAL GERONTOLOGY
- Mitochondrial Dysfunction Confers Resistance to Multiple Drugs in Caenorhabditis elegans
- (2010) Iryna O. Zubovych et al. MOLECULAR BIOLOGY OF THE CELL
- Genome-wide analysis of eukaryotic twin CX9C proteins
- (2010) Gabriele Cavallaro Molecular BioSystems
- A clinico-pathological study of subtypes in Parkinson's disease
- (2009) M. Selikhova et al. BRAIN
- Identification of novel cell migration-promoting genes by a functional genetic screen
- (2009) Minchul Seo et al. FASEB JOURNAL
- Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
- (2009) H. Chen et al. HUMAN MOLECULAR GENETICS
- Non-motor symptoms in Parkinson’s disease
- (2008) W. Poewe EUROPEAN JOURNAL OF NEUROLOGY
- Parkinson's disease: clinical features and diagnosis
- (2008) J Jankovic JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Identification of a Novel Protein MICS1 that is Involved in Maintenance of Mitochondrial Morphology and Apoptotic Release of Cytochrome c
- (2008) Toshihiko Oka et al. MOLECULAR BIOLOGY OF THE CELL
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