Generation of mature and functional hair cells by co-expression of Gfi1, Pou4f3, and Atoh1 in the postnatal mouse cochlea

The therapeutic potential of induced hepatocyte-like cells generated by direct reprogramming on hepatic fibrosis

(2019) Suhyun Park et al.   Stem Cell Research & Therapy

Multiple supporting cell subtypes are capable of spontaneous hair cell regeneration in the neonatal mouse cochlea

(2019) Melissa M. McGovern et al.   DEVELOPMENT

Gata3 is required for the functional maturation of inner hair cells and their innervation in the mouse cochlea

(2019) Tanaya Bardhan et al.   JOURNAL OF PHYSIOLOGY-LONDON

Renewed proliferation in adult mouse cochlea and regeneration of hair cells

(2019) Yilai Shu et al.   Nature Communications

Direct In Vivo Reprogramming with Sendai Virus Vectors Improves Cardiac Function after Myocardial Infarction

(2018) Kazutaka Miyamoto et al.   Cell Stem Cell

Characterization of Lgr6+ Cells as an Enriched Population of Hair Cell Progenitors Compared to Lgr5+ Cells for Hair Cell Generation in the Neonatal Mouse Cochlea

(2018) Yanping Zhang et al.   Frontiers in Molecular Neuroscience

High-resolution transcriptional dissection of in vivo Atoh1-mediated hair cell conversion in mature cochleae identifies Isl1 as a co-reprogramming factor

(2018) Tetsuji Yamashita et al.   PLoS Genetics

Helios is a key transcriptional regulator of outer hair cell maturation

(2018) Lauren Chessum et al.   NATURE

Atoh1 in sensory hair cell development: constraints and cofactors

(2017) Aida Costa et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

In Vivo Interplay between p27 Kip1 , GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice

(2017) Bradley J. Walters et al.   Cell Reports

Inactivation of STAT3 Signaling Impairs Hair Cell Differentiation in the Developing Mouse Cochlea

(2017) Qianqian Chen et al.   Stem Cell Reports

Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes In Vivo Attenuates Liver Fibrosis

(2016) Guangqi Song et al.   Cell Stem Cell

Extensive Supporting Cell Proliferation and Mitotic Hair Cell Generation by In Vivo Genetic Reprogramming in the Neonatal Mouse Cochlea

(2016) Wenli Ni et al.   JOURNAL OF NEUROSCIENCE

Noise induced reversible changes of cochlear ribbon synapses contribute to temporary hearing loss in mice

(2015) Lin Shi et al.   ACTA OTO-LARYNGOLOGICA

Generation of sensory hair cells by genetic programming with a combination of transcription factors

(2015) A. Costa et al.   DEVELOPMENT

Gene Expression by Mouse Inner Ear Hair Cells during Development

(2015) D. I. Scheffer et al.   JOURNAL OF NEUROSCIENCE

In Vivo Cochlear Hair Cell Generation and Survival by Coactivation of  -Catenin and Atoh1

(2015) B. R. Kuo et al.   JOURNAL OF NEUROSCIENCE

Manipulating cell fate in the cochlea: a feasible therapy for hearing loss

(2015) Masato Fujioka et al.   TRENDS IN NEUROSCIENCES

Quantitative High-Resolution Cellular Map of the Organ of Corti

(2015) Jörg Waldhaus et al.   Cell Reports

Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo

(2014) B. C. Cox et al.   DEVELOPMENT

Hey1 and Hey2 Control the Spatial and Temporal Pattern of Mammalian Auditory Hair Cell Differentiation Downstream of Hedgehog Signaling

(2014) A. Benito-Gonzalez et al.   JOURNAL OF NEUROSCIENCE

Transcription Factors with Conserved Binding Sites Near ATOH1 on the POU4F3 Gene Enhance the Induction of Cochlear Hair Cells

(2014) Ryoukichi Ikeda et al.   MOLECULAR NEUROBIOLOGY

Integrating the active process of hair cells with cochlear function

(2014) A. J. Hudspeth   NATURE REVIEWS NEUROSCIENCE

In Vivo Generation of Immature Inner Hair Cells in Neonatal Mouse Cochleae by Ectopic Atoh1 Expression

(2014) Zhiyong Liu et al.   PLoS One

Spontaneous regeneration of cochlear supporting cells after neonatal ablation ensures hearing in the adult mouse

(2014) Marcia M. Mellado Lagarde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway

(2014) Wenyan Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Temporospatial expression and cellular localization of VGLUT3 in the rat cochlea

(2013) Zhe Peng et al.   BRAIN RESEARCH

In vivo reprogramming of astrocytes to neuroblasts in the adult brain

(2013) Wenze Niu et al.   NATURE CELL BIOLOGY

Generation of hair cells in neonatal mice by β-catenin overexpression in Lgr5-positive cochlear progenitors

(2013) Fuxin Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Eya1-Six1 Interaction Is Sufficient to Induce Hair Cell Fate in the Cochlea by Activating Atoh1 Expression in Cooperation with Sox2

(2012) Mohi Ahmed et al.   DEVELOPMENTAL CELL

Conditional Gene Expression in the Mouse Inner Ear Using Cre-loxP

(2012) Brandon C. Cox et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Age-Dependent In Vivo Conversion of Mouse Cochlear Pillar and Deiters' Cells to Immature Hair Cells by Atoh1 Ectopic Expression

(2012) Z. Liu et al.   JOURNAL OF NEUROSCIENCE

Atoh1 Directs the Formation of Sensory Mosaics and Induces Cell Proliferation in the Postnatal Mammalian Cochlea In Vivo

(2012) M. C. Kelly et al.   JOURNAL OF NEUROSCIENCE

Targeting of the Hair Cell Proteins Cadherin 23, Harmonin, Myosin XVa, Espin, and Prestin in an Epithelial Cell Model

(2010) L. Zheng et al.   JOURNAL OF NEUROSCIENCE

Sensorineural Deafness and Seizures in Mice Lacking Vesicular Glutamate Transporter 3

(2008) Rebecca P. Seal et al.   NEURON