High-dimensional profiling clusters asthma severity by lymphoid and non-lymphoid status
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Title
High-dimensional profiling clusters asthma severity by lymphoid and non-lymphoid status
Authors
Keywords
severe asthma, BAL, immune, multi-omics, CyTOF, RNA-seq, clusters, FceRI+, IFN-g, ICLite
Journal
Cell Reports
Volume 35, Issue 2, Pages 108974
Publisher
Elsevier BV
Online
2021-04-15
DOI
10.1016/j.celrep.2021.108974
References
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Note: Only part of the references are listed.- Are We meeting the Promise of Endotypes and Precision Medicine in Asthma
- (2020) Anuradha Ray et al. PHYSIOLOGICAL REVIEWS
- Human Th1 and Th2 Cells Targeting Rhinovirus and Allergen Coordinately Promote Allergic Asthma.
- (2020) Lyndsey M. Muehling et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
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- (2020) Juan Tur et al. Cell Reports
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- (2019) Wei Wu et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Bronchoalveolar Lavage Cell Gene Expression in Severe Asthma Reveals Mechanisms of Severe Disease and Influences of Medications
- (2019) Nathaniel Weathington et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Pulmonary type2 innate lymphoid cells in paediatric severe asthma: phenotype and response to steroids
- (2019) Prasad Nagakumar et al. EUROPEAN RESPIRATORY JOURNAL
- Automated optimized parameters for T-distributed stochastic neighbor embedding improve visualization and analysis of large datasets
- (2019) Anna C. Belkina et al. Nature Communications
- T H 1 signatures are present in the lower airways of children with severe asthma, regardless of allergic status
- (2018) Julia A. Wisniewski et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Elevated Expression of IL-33 and TSLP in the Airways of Human Asthmatics In Vivo: A Potential Biomarker of Severe Refractory Disease
- (2018) Yan Li et al. JOURNAL OF IMMUNOLOGY
- After asthma: redefining airways diseases
- (2018) Ian D Pavord et al. LANCET
- Mitochondrial Dynamics at the Interface of Immune Cell Metabolism and Function
- (2018) Angelika S. Rambold et al. TRENDS IN IMMUNOLOGY
- Tralokinumab for severe, uncontrolled asthma (STRATOS 1 and STRATOS 2): two randomised, double-blind, placebo-controlled, phase 3 clinical trials
- (2018) Reynold A Panettieri et al. Lancet Respiratory Medicine
- Baseline Patient Factor Impact on the Clinical Efficacy of Benralizumab for Severe Asthma
- (2018) Eugene R. Bleecker et al. EUROPEAN RESPIRATORY JOURNAL
- T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED
- (2017) Chih-Hsi Scott Kuo et al. EUROPEAN RESPIRATORY JOURNAL
- Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma
- (2017) Pieter-Paul Hekking et al. EUROPEAN RESPIRATORY JOURNAL
- Biochemical Underpinnings of Immune Cell Metabolic Phenotypes
- (2017) Benjamin A. Olenchock et al. IMMUNITY
- Ex-Th17 (Nonclassical Th1) Cells Are Functionally Distinct from Classical Th1 and Th17 Cells and Are Not Constrained by Regulatory T Cells
- (2017) Sharee A. Basdeo et al. JOURNAL OF IMMUNOLOGY
- Tezepelumab in Adults with Uncontrolled Asthma
- (2017) Jonathan Corren et al. NEW ENGLAND JOURNAL OF MEDICINE
- Reslizumab in patients with inadequately controlled late-onset asthma and elevated blood eosinophils
- (2017) Guy Brusselle et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- Biomarkers of Airway Type-2 Inflammation and Integrating Complex Phenotypes to Endotypes in Asthma
- (2016) Michael C. Peters et al. CURRENT ALLERGY AND ASTHMA REPORTS
- Macrophages in Tissue Repair, Regeneration, and Fibrosis
- (2016) Thomas A. Wynn et al. IMMUNITY
- Current application of exhaled nitric oxide in clinical practice
- (2016) Joseph D. Spahn et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Current concepts of severe asthma
- (2016) Anuradha Ray et al. JOURNAL OF CLINICAL INVESTIGATION
- In Vivo Depletion of CD206+ M2 Macrophages Exaggerates Lung Injury in Endotoxemic Mice
- (2015) Kenta Kambara et al. AMERICAN JOURNAL OF PATHOLOGY
- Evolving Concepts of Asthma
- (2015) Marc Gauthier et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- FlowSOM: Using self-organizing maps for visualization and interpretation of cytometry data
- (2015) Sofie Van Gassen et al. CYTOMETRY PART A
- High IFN-γ and low SLPI mark severe asthma in mice and humans
- (2015) Mahesh Raundhal et al. JOURNAL OF CLINICAL INVESTIGATION
- RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection
- (2015) Agnieszka Jozwik et al. Nature Communications
- Efficacy and safety of tralokinumab in patients with severe uncontrolled asthma: a randomised, double-blind, placebo-controlled, phase 2b trial
- (2015) Christopher E Brightling et al. Lancet Respiratory Medicine
- Gene Expression in Relation to Exhaled Nitric Oxide Identifies Novel Asthma Phenotypes with Unique Biomolecular Pathways
- (2014) Brian D. Modena et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Sputum gene expression signature of 6 biomarkers discriminates asthma inflammatory phenotypes
- (2014) Katherine J. Baines et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert
- (2014) S. Ariotti et al. SCIENCE
- Exploring the Effects of Omalizumab in Allergic Asthma
- (2013) Nicola A. Hanania et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
- (2013) Y. Liao et al. BIOINFORMATICS
- International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
- (2013) K. F. Chung et al. EUROPEAN RESPIRATORY JOURNAL
- Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects
- (2013) Annette T. Hastie et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Dupilumab in Persistent Asthma with Elevated Eosinophil Levels
- (2013) Sally Wenzel et al. NEW ENGLAND JOURNAL OF MEDICINE
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection
- (2012) Fei Chen et al. NATURE MEDICINE
- Asthma phenotypes: the evolution from clinical to molecular approaches
- (2012) Sally E Wenzel NATURE MEDICINE
- Essentials of the self-organizing map
- (2012) Teuvo Kohonen NEURAL NETWORKS
- Severe Asthma
- (2011) Nizar N. Jarjour et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Sparse PLS discriminant analysis: biologically relevant feature selection and graphical displays for multiclass problems
- (2011) Kim-Anh Lê Cao et al. BMC BIOINFORMATICS
- Costs of asthma in the United States: 2002-2007
- (2011) Sarah Beth L. Barnett et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma
- (2009) Prescott G. Woodruff et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Genome-wide Analysis of Histone Methylation Reveals Chromatin State-Based Regulation of Gene Transcription and Function of Memory CD8+ T Cells
- (2009) Yasuto Araki et al. IMMUNITY
- Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation
- (2009) Melanie A. Kleinschek et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cluster Analysis and Clinical Asthma Phenotypes
- (2008) Pranab Haldar et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- WGCNA: an R package for weighted correlation network analysis
- (2008) Peter Langfelder et al. BMC BIOINFORMATICS
- Differential expression of CD26 on virus-specific CD8+T cells during active, latent and resolved infection
- (2008) Chris C. Ibegbu et al. IMMUNOLOGY
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