EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission

SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance

(2021) Manuel Rogg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Basement Membrane Regulates Fibronectin Organization Using Sliding Focal Adhesions Driven by a Contractile Winch

(2020) Jiaoyang Lu et al.   DEVELOPMENTAL CELL

Basement membrane ligands initiate distinct signalling networks to direct cell shape

(2020) Michael J. Randles et al.   MATRIX BIOLOGY

Pan-Cancer Analyses Reveal Genomic Features of FOXM1 Overexpression in Cancer

(2019) Carter Barger et al.   Cancers

CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing

(2019) Kornel Labun et al.   NUCLEIC ACIDS RESEARCH

Integrins as biomechanical sensors of the microenvironment

(2019) Jenny Z. Kechagia et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

α-Integrins dictate distinct modes of type IV collagen recruitment to basement membranes

(2019) Ranjay Jayadev et al.   JOURNAL OF CELL BIOLOGY

Mutations in PDLIM5 are rare in dilated cardiomyopathy but are emerging as potential disease modifiers

(2019) Job A. J. Verdonschot et al.   Molecular Genetics & Genomic Medicine

The relationship between the thickness of glomerular basement membrane and renal outcomes in patients with diabetic nephropathy

(2018) Junlin Zhang et al.   ACTA DIABETOLOGICA

Alport syndrome and Pierson syndrome: Diseases of the glomerular basement membrane

(2018) Steven D. Funk et al.   MATRIX BIOLOGY

FERMT2 links cortical actin structures, plasma membrane tension and focal adhesion function to stabilize podocyte morphology

(2018) M. Yasuda-Yamahara et al.   MATRIX BIOLOGY

Basement membrane mechanics shape development: Lessons from the fly

(2018) William Ramos-Lewis et al.   MATRIX BIOLOGY

AIF1L regulates actomyosin contractility and filopodial extensions in human podocytes

(2018) Mako Yasuda-Yamahara et al.   PLoS One

Disease-causing mutation in α-actinin-4 promotes podocyte detachment through maladaptation to periodic stretch

(2018) Di Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes

(2018) Markus M. Rinschen et al.   Cell Reports

Basement Membrane Defects in Genetic Kidney Diseases

(2018) Christine Chew et al.   Frontiers in Pediatrics

ARP3 Controls the Podocyte Architecture at the Kidney Filtration Barrier

(2018) Christoph Schell et al.   DEVELOPMENTAL CELL

Enigma proteins regulate YAP mechanotransduction

(2018) Ahmed Elbediwy et al.   JOURNAL OF CELL SCIENCE

Integrin activation by talin, kindlin and mechanical forces

(2018) Zhiqi Sun et al.   NATURE CELL BIOLOGY

Integrin and dystroglycan compensate each other to mediate laminin-dependent basement membrane assembly and epiblast polarization

(2017) Shaohua Li et al.   MATRIX BIOLOGY

Cell-derived matrices for studying cell proliferation and directional migration in a complex 3D microenvironment

(2017) Riina Kaukonen et al.   Nature Protocols

Stressed podocytes—mechanical forces, sensors, signaling and response

(2017) Karlhans Endlich et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Integrin extension enables ultrasensitive regulation by cytoskeletal force

(2017) Jing Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier

(2017) Christoph Schell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The WD40-domain containing protein CORO2B is specifically enriched in glomerular podocytes and regulates the ventral actin cytoskeleton

(2017) M. Rogg et al.   Scientific Reports

The extracellular matrix: Tools and insights for the “omics” era

(2016) Alexandra Naba et al.   MATRIX BIOLOGY

Identification of Protease Specificity by Combining Proteome-Derived Peptide Libraries and Quantitative Proteomics

(2016) Martin L. Biniossek et al.   MOLECULAR & CELLULAR PROTEOMICS

α-Actinin links extracellular matrix rigidity-sensing contractile units with periodic cell-edge retractions

(2016) Giovanni Meacci et al.   MOLECULAR BIOLOGY OF THE CELL

Podocyte–actin dynamics in health and disease

(2016) Luca Perico et al.   Nature Reviews Nephrology

An active role for basement membrane assembly and modification in tissue sculpting

(2015) M. A. Morrissey et al.   JOURNAL OF CELL SCIENCE

Podocyte-Specific Deletion of Murine CXADR Does Not Impair Podocyte Development, Function or Stress Response

(2015) Christoph Schell et al.   PLoS One

Proteomic analysis of integrin-associated complexes from mesenchymal stem cells

(2015) Jila N. Ajeian et al.   Proteomics Clinical Applications

Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance

(2014) Xuefei Tian et al.   JOURNAL OF CLINICAL INVESTIGATION

Glomerular Cell Cross-Talk Influences Composition and Assembly of Extracellular Matrix

(2014) A. Byron et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Global Analysis Reveals the Complexity of the Human Glomerular Extracellular Matrix

(2014) R. Lennon et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

Mechanotransduction and extracellular matrix homeostasis

(2014) Jay D. Humphrey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Extracellular matrix assembly: a multiscale deconstruction

(2014) Janna K. Mouw et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The integrin adhesome: from genes and proteins to human disease

(2014) Sabina E. Winograd-Katz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Importance of Podocyte Adhesion for a Healthy Glomerulus

(2014) Rachel Lennon et al.   Frontiers in Endocrinology

N-WASP Is Required for Stabilization of Podocyte Foot Processes

(2013) C. Schell et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks

(2013) Melanie Boerries et al.   KIDNEY INTERNATIONAL

The glomerular basement membrane as a barrier to albumin

(2013) Jung Hee Suh et al.   Nature Reviews Nephrology

The podocyte slit diaphragm—from a thin grey line to a complex signalling hub

(2013) Florian Grahammer et al.   Nature Reviews Nephrology

Integrin-dependent force transmission to the extracellular matrix by  -actinin triggers adhesion maturation

(2013) P. Roca-Cusachs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Laminins in basement membrane assembly

(2013) Erhard Hohenester et al.   Cell Adhesion & Migration

Nanoscale protein architecture of the kidney glomerular basement membrane

(2013) Hani Suleiman et al.   eLife

Gain of glycosylation in integrin α3 causes lung disease and nephrotic syndrome

(2012) Nayia Nicolaou et al.   JOURNAL OF CLINICAL INVESTIGATION

Integrin α3Mutations with Kidney, Lung, and Skin Disease

(2012) Cristina Has et al.   NEW ENGLAND JOURNAL OF MEDICINE

Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins

(2011) Herbert B Schiller et al.   EMBO REPORTS

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

(2011) Jean-Cheng Kuo et al.   NATURE CELL BIOLOGY

Overview of the Matrisome--An Inventory of Extracellular Matrix Constituents and Functions

(2011) R. O. Hynes et al.   Cold Spring Harbor Perspectives in Biology

Laminin deposition in the extracellular matrix: a complex picture emerges

(2009) Kevin J. Hamill et al.   JOURNAL OF CELL SCIENCE

β1 integrin expression by podocytes is required to maintain glomerular structural integrity

(2008) Ambra Pozzi et al.   DEVELOPMENTAL BIOLOGY

EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial–mesenchymal transition

(2008) Mariko Hirano et al.   JOURNAL OF CELL BIOLOGY

RhoA and microtubule dynamics control cell–basement membrane interaction in EMT during gastrulation

(2008) Yukiko Nakaya et al.   NATURE CELL BIOLOGY