The DEAD-box helicase DDX56 is a conserved stemness regulator in normal and cancer stem cells

Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy

(2020) Charles P. Couturier et al.   Nature Communications

One Stem Cell Program to Rule Them All?

(2020) Mallory Wiggans et al.   FEBS Journal

Cell-of-origin susceptibility to glioblastoma formation declines with neural lineage restriction

(2019) Sheila Alcantara Llaguno et al.   NATURE NEUROSCIENCE

CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing

(2019) Kornel Labun et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells

(2019) Graham MacLeod et al.   Cell Reports

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma

(2019) Cyril Neftel et al.   CELL

Signal Transduction in Ribosome Biogenesis: A Recipe to Avoid Disaster

(2019) Manuela Piazzi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

DDX56 inhibits type I interferon by disrupting assembly of IRF3–IPO5 to inhibit IRF3 nucleus import

(2019) Dan Li et al.   JOURNAL OF CELL SCIENCE

The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma

(2019) Bengt Phung et al.   Cell Reports

DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome

(2019) Parimal Samir et al.   NATURE

DEAD-box ATPases are global regulators of phase-separated organelles

(2019) Maria Hondele et al.   NATURE

The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis

(2019) Bruno Di Stefano et al.   Cell Stem Cell

Prospectively Isolated Tetraspanin + Neoblasts Are Adult Pluripotent Stem Cells Underlying Planaria Regeneration

(2018) An Zeng et al.   CELL

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

(2018) Tathiane M. Malta et al.   CELL

EvoRegen in animals: Time to uncover deep conservation or convergence of adult stem cell evolution and regenerative processes

(2018) Alvina G. Lai et al.   DEVELOPMENTAL BIOLOGY

Cell type transcriptome atlas for the planarianSchmidtea mediterranea

(2018) Christopher T. Fincher et al.   SCIENCE

Cell type atlas and lineage tree of a whole complex animal by single-cell transcriptomics

(2018) Mireya Plass et al.   SCIENCE

The genome of Schmidtea mediterranea and the evolution of core cellular mechanisms

(2018) Markus Alexander Grohme et al.   NATURE

Human glioblastoma arises from subventricular zone cells with low-level driver mutations

(2018) Joo Ho Lee et al.   NATURE

A Human Adult Stem Cell Signature Marks Aggressive Variants across Epithelial Cancers

(2018) Bryan A. Smith et al.   Cell Reports

P68 RNA helicase promotes invasion of glioma cells through negatively regulating DUSP5

(2018) Rui Wang et al.   CANCER SCIENCE

Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate

(2018) Ze Cheng et al.   MOLECULAR CELL

A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression

(2018) Xin Chen et al.   NEURON

Smed-myb-1 Specifies Early Temporal Identity during Planarian Epidermal Differentiation

(2018) Shu Jun Zhu et al.   Cell Reports

Wanted DEAD/H or Alive: Helicases Winding Up in Cancers

(2017) Wanpei Cai et al.   JNCI-Journal of the National Cancer Institute

Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy

(2017) Xiaoyang Lan et al.   NATURE

Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain

(2017) Anastassia Voronova et al.   NEURON

Cancer stem cells: The root of tumor recurrence and metastases

(2017) Claudia Peitzsch et al.   SEMINARS IN CANCER BIOLOGY

Yorkie is required to restrict the injury responses in planarians

(2017) Alexander Y. T. Lin et al.   PLoS Genetics

Wanted DEAD/H or Alive: Helicases Winding Up in Cancers

(2017) Wanpei Cai et al.   JNCI-Journal of the National Cancer Institute

The EGFR signaling pathway controls gut progenitor differentiation during planarian regeneration and homeostasis

(2016) Sara Barberán et al.   DEVELOPMENT

Egf Signaling Directs Neoblast Repopulation by Regulating Asymmetric Cell Division in Planarians

(2016) Kai Lei et al.   DEVELOPMENTAL CELL

Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress

(2016) Emilien Nicolas et al.   Nature Communications

HOX gene complement and expression in the planarian Schmidtea mediterranea

(2016) Ko W. Currie et al.   EvoDevo

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

(2015) Traver Hart et al.   CELL

A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis

(2015) Gianluca Amadei et al.   JOURNAL OF NEUROSCIENCE

StemChecker: a web-based tool to discover and explore stemness signatures in gene sets

(2015) José P. Pinto et al.   NUCLEIC ACIDS RESEARCH

The ancestral gene repertoire of animal stem cells

(2015) Alexandre Alié et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A mex3 homolog is required for differentiation during planarian stem cell lineage development

(2015) Shu Jun Zhu et al.   eLife

Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells

(2014) Mario L. Suvà et al.   CELL

p63 and p73 coordinate p53 function to determine the balance between survival, cell death and senescence in adult neural precursor cells

(2014) M P Fatt et al.   CELL DEATH AND DIFFERENTIATION

Evolution of the Cancer Stem Cell Model

(2014) Antonija Kreso et al.   Cell Stem Cell

Planarian yorkie/YAP functions to integrate adult stem cell proliferation, organ homeostasis and maintenance of axial patterning

(2014) A. Y. T. Lin et al.   DEVELOPMENT

Emerging treatment strategies for glioblastoma multiforme

(2014) S. K. Carlsson et al.   EMBO Molecular Medicine

Snail Coordinately Regulates Downstream Pathways to Control Multiple Aspects of Mammalian Neural Precursor Development

(2014) M. A. Zander et al.   JOURNAL OF NEUROSCIENCE

Contribution of p53 to Metastasis

(2014) E. Powell et al.   Cancer Discovery

Nucleolar stress with and without p53

(2014) Allison James et al.   Nucleus

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

A Tumorigenic MLL-Homeobox Network in Human Glioblastoma Stem Cells

(2012) M. Gallo et al.   CANCER RESEARCH

Genetic Regulators of a Pluripotent Adult Stem Cell System in Planarians Identified by RNAi and Clonal Analysis

(2012) Daniel E. Wagner et al.   Cell Stem Cell

An Asymmetrically Localized Staufen2-Dependent RNA Complex Regulates Maintenance of Mammalian Neural Stem Cells

(2012) John P. Vessey et al.   Cell Stem Cell

TORC1 is required to balance cell proliferation and cell death in planarians

(2012) Kimberly C. Tu et al.   DEVELOPMENTAL BIOLOGY

The Retinoblastoma pathway regulates stem cell proliferation in freshwater planarians

(2012) Shu Jun Zhu et al.   DEVELOPMENTAL BIOLOGY

Gene expression of pluripotency determinants is conserved between mammalian and planarian stem cells

(2012) Pinar Önal et al.   EMBO JOURNAL

A restricted cell population propagates glioblastoma growth after chemotherapy

(2012) Jian Chen et al.   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

A Comparative Transcriptomic Analysis Reveals Conserved Features of Stem Cell Pluripotency in Planarians and Mammals

(2012) Roselyne M. Labbé et al.   STEM CELLS

Transcriptome Analysis of the Planarian Eye Identifies ovo as a Specific Regulator of Eye Regeneration

(2012) Sylvain W. Lapan et al.   Cell Reports

Defining the molecular profile of planarian pluripotent stem cells using a combinatorial RNA-seq, RNA interference and irradiation approach

(2012) Jordi Solana et al.   GENOME BIOLOGY

Two-color fluorescent in situ hybridization in the embryonic zebrafish brain using differential detection systems

(2011) Gilbert Lauter et al.   BMC DEVELOPMENTAL BIOLOGY

Genome-Wide Analysis of Self-Renewal in Drosophila Neural Stem Cells by Transgenic RNAi

(2011) Ralph A. Neumüller et al.   Cell Stem Cell

EGFR signaling regulates cell proliferation, differentiation and morphogenesis during planarian regeneration and homeostasis

(2011) Susanna Fraguas et al.   DEVELOPMENTAL BIOLOGY

The Capsid-Binding Nucleolar Helicase DDX56 Is Important for Infectivity of West Nile Virus

(2011) Z. Xu et al.   JOURNAL OF VIROLOGY

Stem cell gene expression programs influence clinical outcome in human leukemia

(2011) Kolja Eppert et al.   NATURE MEDICINE

Enhancer-driven membrane markers for analysis of nonautonomous mechanisms reveal neuron-glia interactions in Drosophila

(2011) C. Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clonogenic Neoblasts Are Pluripotent Adult Stem Cells That Underlie Planarian Regeneration

(2011) D. E. Wagner et al.   SCIENCE

Planarian stem cells: a simple paradigm for regeneration

(2011) A. Aziz Aboobaker   TRENDS IN CELL BIOLOGY

Cancer Stem Cells and Self-renewal

(2010) C. A. O'Brien et al.   CLINICAL CANCER RESEARCH

Planarian regeneration involves distinct stem cell responses to wounds and tissue absence

(2010) Danielle Wenemoser et al.   DEVELOPMENTAL BIOLOGY

Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation

(2010) Daniele Merico et al.   PLoS One

Genetic alterations and signaling pathways in the evolution of gliomas

(2009) Hiroko Ohgaki et al.   CANCER SCIENCE

Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens

(2009) Steven M. Pollard et al.   Cell Stem Cell

A planarian p53 homolog regulates proliferation and self-renewal in adult stem cell lineages

(2009) Bret J. Pearson et al.   DEVELOPMENT

Cell death and tissue remodeling in planarian regeneration

(2009) Jason Pellettieri et al.   DEVELOPMENTAL BIOLOGY

Formaldehyde-based whole-mount in situ hybridization method for planarians

(2009) Bret J. Pearson et al.   DEVELOPMENTAL DYNAMICS

Genomic aberrations in 80 cases of primary glioblastoma multiforme: Pathogenetic heterogeneity and putative cytogenetic pathways

(2009) Hanne-Sofie S. Dahlback et al.   GENES CHROMOSOMES & CANCER

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

A Drosophila Model for EGFR-Ras and PI3K-Dependent Human Glioma

(2009) Renee D. Read et al.   PLoS Genetics

Molecular Analysis of Stem Cells and Their Descendants during Cell Turnover and Regeneration in the Planarian Schmidtea mediterranea

(2008) George T. Eisenhoffer et al.   Cell Stem Cell

Planarian PTEN homologs regulate stem cells and regeneration through TOR signaling

(2008) N. J. Oviedo et al.   Disease Models & Mechanisms

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Selective Pharmacological Targeting of a DEAD Box RNA Helicase

(2008) Lisa Lindqvist et al.   PLoS One

 -Catenin Defines Head Versus Tail Identity During Planarian Regeneration and Homeostasis

(2007) K. A. Gurley et al.   SCIENCE