The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

Yap suppresses T-cell function and infiltration in the tumor microenvironment

(2020) Eleni Stampouloglou et al.   PLOS BIOLOGY

Severe asthma in children—a review of definitions, epidemiology, and treatment options in 2019

(2019) Husam Ahmed et al.   PEDIATRIC PULMONOLOGY

Involvement of microRNAs in physiological and pathological processes in asthma

(2019) Seyed Reza Mousavi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

IgM anti-phosphorylcholine antibodies associate with senescent and IL-17+ T cells in SLE patients with a pro-inflammatory lipid profile

(2019) Patricia López et al.   RHEUMATOLOGY

Epidemiology of Asthma in Children and Adults

(2019) Shyamali C. Dharmage et al.   Frontiers in Pediatrics

MICRORNA-221 IS OVEREXPRESSED IN THE EQUINE ASTHMATIC AIRWAY SMOOTH MUSCLE AND MODULATES SMOOTH MUSCLE CELL PROLIFERATION.

(2019) Mohamed Issouf et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Inhibiting the Notch signaling pathway suppresses Th17-associated airway hyperresponsiveness in obese asthmatic mice

(2019) Zeyu Zeng et al.   LABORATORY INVESTIGATION

MicroRNA-30a Targets ATG5 and Attenuates Airway Fibrosis in Asthma by Suppressing Autophagy

(2019) Bin Bin Li et al.   INFLAMMATION

Asthma in Adults

(2019) Anil Nanda et al.   MEDICAL CLINICS OF NORTH AMERICA

Sphingosine-1-phosphate induces airway smooth muscle cells proliferation, migration and contraction by modulating Hippo signaling effector YAP

(2018) Lu Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

MiR-150-5p regulates EGR2 to promote the development of chronic rhinosinusitis via the DC-Th axis

(2018) Zuxia Ma et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mannose receptor modulates macrophage polarization and allergic inflammation through miR-511-3p

(2018) Yufeng Zhou et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lipid profiles in adolescents with and without asthma: Korea National Health and nutrition examination survey data

(2018) Sun-Hye Ko et al.   Lipids in Health and Disease

YAP Is Essential for Treg-Mediated Suppression of Antitumor Immunity

(2018) Xuhao Ni et al.   Cancer Discovery

Paracrine HGF/c-MET enhances the stem cell-like potential and glycolysis of pancreatic cancer cells via activation of YAP/HIF-1α

(2018) Bin Yan et al.   EXPERIMENTAL CELL RESEARCH

Yes-associated protein (YAP) binds to HIF-1α and sustains HIF-1α protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress

(2018) Xiaodong Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

MBD2 regulates differentiation and function of Th17 cells in neutrophils- dominant asthma via HIF-1α

(2018) Li Xu et al.   Journal of Inflammation-London

Th17/Treg homeostasis, but not Th1/Th2 homeostasis, is implicated in exacerbation of human bronchial asthma

(2018) Xiao-ling Zou et al.   Therapeutics and Clinical Risk Management

microRNA cluster 106a~363 is involved in T helper 17 cell differentiation

(2017) Marc Kästle et al.   IMMUNOLOGY

Oroxylin A prevents angiogenesis of LSECs in liver fibrosis via inhibition of YAP/HIF-1α signaling

(2017) Chenxi Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mouse models of severe asthma: Understanding the mechanisms of steroid resistance, tissue remodelling and disease exacerbation

(2017) Steven Maltby et al.   RESPIROLOGY

Investigation of the Possible Role of the Hippo/YAP1 Pathway in Asthma and Allergy

(2017) Lili E. Fodor et al.   Allergy Asthma & Immunology Research

Progress in the understanding of the pathology of allergic asthma and the potential of fruit proanthocyanidins as modulators of airway inflammation

(2017) Sara L. Coleman et al.   Food & Function

Asthma Exacerbations: Pathogenesis, Prevention, and Treatment

(2017) Jamee R. Castillo et al.   Journal of Allergy and Clinical Immunology-In Practice

Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s

(2016) Jakob von Moltke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

RBP-J–Regulated miR-182 Promotes TNF-α–Induced Osteoclastogenesis

(2016) Christine H. Miller et al.   JOURNAL OF IMMUNOLOGY

Transcription Factor Bcl11b Controls Identity and Function of Mature Type 2 Innate Lymphoid Cells

(2015) Danielle Califano et al.   IMMUNITY

Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells

(2015) Claudia U Duerr et al.   NATURE IMMUNOLOGY

microRNAs as Developmental Regulators

(2015) Kathryn N. Ivey et al.   Cold Spring Harbor Perspectives in Biology

Hypoxia-inducible miR-182 enhances HIF1α signaling via targeting PHD2 and FIH1 in prostate cancer

(2015) Yan Li et al.   Scientific Reports

Asthma: definitions and pathophysiology

(2015) James W. Mims   International Forum of Allergy & Rhinology

Immune surveillance of the lung by migrating tissue monocytes

(2015) Mathieu P Rodero et al.   eLife

Allergic rhinitis and asthma: Epidemiology and common pathophysiology

(2014) David A. Khan   ALLERGY AND ASTHMA PROCEEDINGS

IL-17 in Severe Asthma. Where Do We Stand?

(2014) Julie Chesné et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

EGR2 is critical for peripheral naïve T-cell differentiation and the T-cell response to influenza

(2014) Ning Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nr4a1-Dependent Ly6Clow Monocytes Monitor Endothelial Cells and Orchestrate Their Disposal

(2013) Leo M. Carlin et al.   CELL

Hypoxia potentiates allergen induction of HIF-1α, chemokines, airway inflammation, TGF-β1, and airway remodeling in a mouse model

(2013) Kwang Je Baek et al.   CLINICAL IMMUNOLOGY

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

(2013) Fernando Calvo et al.   NATURE CELL BIOLOGY

Global asthma prevalence in adults: findings from the cross-sectional world health survey

(2012) Teresa To et al.   BMC PUBLIC HEALTH

Early Growth Response Gene-2 Controls IL-17 Expression and Th17 Differentiation by Negatively Regulating Batf

(2012) T. Miao et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Intravascular Staining Redefines Lung CD8 T Cell Responses

(2012) K. G. Anderson et al.   JOURNAL OF IMMUNOLOGY

Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil function

(2012) Laura E. Crotty Alexander et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The Asparaginyl Hydroxylase Factor Inhibiting HIF-1α Is an Essential Regulator of Metabolism

(2010) Na Zhang et al.   Cell Metabolism

An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells

(2010) Woo-Yong Lee et al.   NATURE IMMUNOLOGY

TH-17 Cell-Related Cytokines' Potential Role in the Pathogenesis of Severe Asthma

(2008) Wisam Al-Ramli et al.   JOURNAL OF ASTHMA