Behavioral flexibility in a mouse model for obsessive-compulsive disorder: Impaired Pavlovian reversal learning in SAPAP3 mutants

Differential Effects of Deep Brain Stimulation of the Internal Capsule and the Striatum on Excessive Grooming in Sapap3 Mutant Mice

(2018) Cindy M. Pinhal et al.   BIOLOGICAL PSYCHIATRY

Functional heterogeneity within the rodent lateral orbitofrontal cortex dissociates outcome devaluation and reversal learning deficits

(2018) Marios C Panayi et al.   eLife

Impaired instrumental reversal learning is associated with increased medial prefrontal cortex activity in Sapap3 knockout mouse model of compulsive behavior

(2018) Elizabeth E. Manning et al.   NEUROPSYCHOPHARMACOLOGY

Automated classification of self-grooming in mice using open-source software

(2017) Bastijn J.G. van den Boom et al.   JOURNAL OF NEUROSCIENCE METHODS

The neural basis of reversal learning: An updated perspective

(2017) A. Izquierdo et al.   NEUROSCIENCE

Cognitive inflexibility in Obsessive-Compulsive Disorder

(2017) Patricia Gruner et al.   NEUROSCIENCE

Neural basis of impaired safety signaling in Obsessive Compulsive Disorder

(2017) Annemieke M. Apergis-Schoute et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversal learning in patients with obsessive-compulsive disorder (OCD) and their unaffected relatives: Is orbitofrontal dysfunction an endophenotype of OCD?

(2017) Didem Tezcan et al.   PSYCHIATRY RESEARCH

Cognitive Dysfunction in Obsessive-Compulsive Disorder

(2016) Nabil Benzina et al.   Current Psychiatry Reports

Sign Tracking, but Not Goal Tracking, is Resistant to Outcome Devaluation

(2015) Sara E. Morrison et al.   Frontiers in Neuroscience

Effects of orbitofrontal cortex lesions on autoshaped lever pressing and reversal learning

(2014) Stephen E. Chang   BEHAVIOURAL BRAIN RESEARCH

Model-based and model-free Pavlovian reward learning: Revaluation, revision, and revelation

(2014) Peter Dayan et al.   COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE

Reversal Learning as a Neuropsychological Indicator for the Neuropathology of Obsessive Compulsive Disorder? A Behavioral Study

(2014) Gabriele Valerius et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

Circuit-Selective Striatal Synaptic Dysfunction in the Sapap3 Knockout Mouse Model of Obsessive-Compulsive Disorder

(2013) Yehong Wan et al.   BIOLOGICAL PSYCHIATRY

Spatial behavior reflects the mental disorder in OCD patients with and without comorbid schizophrenia

(2013) Anat Gershoni et al.   CNS SPECTRUMS

The touchscreen operant platform for testing learning and memory in rats and mice

(2013) Alexa E Horner et al.   Nature Protocols

Cognitive Inflexibility in Obsessive-Compulsive Disorder and Major Depression Is Associated with Distinct Neural Correlates

(2013) Peter L. Remijnse et al.   PLoS One

Optogenetic Stimulation of Lateral Orbitofronto-Striatal Pathway Suppresses Compulsive Behaviors

(2013) E. Burguiere et al.   SCIENCE

Repeated Cortico-Striatal Stimulation Generates Persistent OCD-Like Behavior

(2013) S. E. Ahmari et al.   SCIENCE

Dopaminergic control of cognitive flexibility in humans and animals

(2013) Marianne Klanker et al.   Frontiers in Neuroscience

JAABA: interactive machine learning for automatic annotation of animal behavior

(2012) Mayank Kabra et al.   NATURE METHODS

Neurobiology of obsessive–compulsive disorder: insights into neural circuitry dysfunction through mouse genetics

(2011) Jonathan T Ting et al.   CURRENT OPINION IN NEUROBIOLOGY

Glutamate abnormalities in obsessive compulsive disorder: Neurobiology, pathophysiology, and treatment

(2011) Christopher Pittenger et al.   PHARMACOLOGY & THERAPEUTICS

Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways

(2011) Mohammed R. Milad et al.   TRENDS IN COGNITIVE SCIENCES

Neurocognitive endophenotypes of impulsivity and compulsivity: towards dimensional psychiatry

(2011) Trevor W. Robbins et al.   TRENDS IN COGNITIVE SCIENCES

Executive Dysfunctions in Obsessive-Compulsive Patients and Unaffected Relatives: Searching for a New Intermediate Phenotype

(2010) Paolo Cavedini et al.   BIOLOGICAL PSYCHIATRY

Orbitofrontal inactivation impairs reversal of Pavlovian learning by interfering with ‘disinhibition’ of responding for previously unrewarded cues

(2009) Kathryn A. Burke et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Obsessive-compulsive disorder

(2009) Jonathan S Abramowitz et al.   LANCET

An Animal Model of Genetic Vulnerability to Behavioral Disinhibition and Responsiveness to Reward-Related Cues: Implications for Addiction

(2009) Shelly B Flagel et al.   NEUROPSYCHOPHARMACOLOGY

Differential frontal–striatal and paralimbic activity during reversal learning in major depressive disorder and obsessive–compulsive disorder

(2009) P. L. Remijnse et al.   PSYCHOLOGICAL MEDICINE

Sapap3and pathological grooming in humans: Results from the OCD collaborative genetics study

(2008) O.J. Bienvenu et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Dissociating the Predictive and Incentive Motivational Properties of Reward-Related Cues Through the Study of Individual Differences

(2008) Terry E. Robinson et al.   BIOLOGICAL PSYCHIATRY

Multiple rare SAPAP3 missense variants in trichotillomania and OCD

(2008) S Züchner et al.   MOLECULAR PSYCHIATRY

The epidemiology of obsessive-compulsive disorder in the National Comorbidity Survey Replication

(2008) A M Ruscio et al.   MOLECULAR PSYCHIATRY

Shifting set about task switching: Behavioral and neural evidence for distinct forms of cognitive flexibility

(2008) Susan M. Ravizza et al.   NEUROPSYCHOLOGIA

Orbitofrontal Dysfunction in Patients with Obsessive-Compulsive Disorder and Their Unaffected Relatives

(2008) S. R. Chamberlain et al.   SCIENCE