Folate transporter dynamics and therapy with classic and tumor-targeted antifolates
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Folate transporter dynamics and therapy with classic and tumor-targeted antifolates
Authors
Keywords
-
Journal
Scientific Reports
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-03-19
DOI
10.1038/s41598-021-85818-x
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Therapeutic Targeting of Mitochondrial One-Carbon Metabolism in Cancer
- (2020) Aamod S. Dekhne et al. MOLECULAR CANCER THERAPEUTICS
- Cellular Pharmacodynamics of a Novel Pyrrolo[3,2-d]pyrimidine Inhibitor Targeting Mitochondrial and Cytosolic One-Carbon Metabolism
- (2019) Aamod S. Dekhne et al. MOLECULAR PHARMACOLOGY
- Fluorine-Substituted Pyrrolo[2,3-d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis
- (2018) Manasa Ravindra et al. JOURNAL OF MEDICINAL CHEMISTRY
- Abstract 3983: Tumor-targeting with novel dual-targeted 6-substituted thieno[2,3-d]pyrimidine antifolates via cellular uptake by folate receptor α, and inhibition of de novo purine nucleotide biosynthesis
- (2018) Adrianne Wallace-Povirk et al. CANCER RESEARCH
- The proton-coupled folate transporter (PCFT-SLC46A1) and the syndrome of systemic and cerebral folate deficiency of infancy: Hereditary folate malabsorption
- (2017) Rongbao Zhao et al. MOLECULAR ASPECTS OF MEDICINE
- Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3- d ]pyrimidine Antifolates
- (2017) Zhanjun Hou et al. MOLECULAR CANCER THERAPEUTICS
- Concordance of folate receptor-α expression between biopsy, primary tumor and metastasis in breast cancer and lung cancer patients
- (2016) Leonora S.F. Boogerd et al. Oncotarget
- 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human Tumors
- (2015) Lei Wang et al. JOURNAL OF MEDICINAL CHEMISTRY
- A current review of folate receptor alpha as a potential tumor target in non-small-cell lung cancer
- (2015) Zhehai Wang et al. Drug Design Development and Therapy
- A Comparative Analysis of Constitutive Promoters Located in Adeno-Associated Viral Vectors
- (2014) Lkhagvasuren Damdindorj et al. PLoS One
- Therapeutic targeting malignant mesothelioma with a novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate via its selective uptake by the proton-coupled folate transporter
- (2013) Christina Cherian et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- pH sensing and regulation in cancer
- (2013) Mehdi Damaghi et al. Frontiers in Physiology
- The human proton-coupled folate transporter
- (2012) Sita Kugel Desmoulin et al. CANCER BIOLOGY & THERAPY
- The Antifolates
- (2012) Michele Visentin et al. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
- Identification and Functional Impact of Homo-oligomers of the Human Proton-coupled Folate Transporter
- (2011) Zhanjun Hou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Synthesis, Biological, and Antitumor Activity of a Highly Potent 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolate Inhibitor with Proton-Coupled Folate Transporter and Folate Receptor Selectivity over the Reduced Folate Carrier That Inhibits β-Glycinamide Ribonucleotide Formyltransferase
- (2011) Lei Wang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter
- (2011) S. Kugel Desmoulin et al. MOLECULAR PHARMACOLOGY
- Compartmentalization of Mammalian Folate-Mediated One-Carbon Metabolism
- (2010) Anne S. Tibbetts et al. Annual Review of Nutrition
- Targeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid Tumors
- (2010) S. K. Desmoulin et al. MOLECULAR PHARMACOLOGY
- Systematic Comparison of Constitutive Promoters and the Doxycycline-Inducible Promoter
- (2010) Jane Yuxia Qin et al. PLoS One
- Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues
- (2009) Rongbao Zhao et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Synthesis and Biological Activity of a Novel Series of 6-Substituted Thieno[2,3-d]pyrimidine Antifolate Inhibitors of Purine Biosynthesis with Selectivity for High Affinity Folate Receptors over the Reduced Folate Carrier and Proton-Coupled Folate Transporter for Cellular Entry†
- (2009) Yijun Deng et al. JOURNAL OF MEDICINAL CHEMISTRY
- Functional characterization of PCFT/HCP1 as the molecular entity of the carrier-mediated intestinal folate transport system in the rat model
- (2008) Katsuhisa Inoue et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Oligomeric Structure of the Human Reduced Folate Carrier
- (2008) Zhanjun Hou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Role for the Proton-coupled Folate Transporter (PCFT-SLC46A1) in Folate Receptor-mediated Endocytosis
- (2008) Rongbao Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Synthesis and Discovery of High Affinity Folate Receptor-Specific Glycinamide Ribonucleotide Formyltransferase Inhibitors with Antitumor Activity
- (2008) Yijun Deng et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Proton-Coupled Folate Transporter: Impact on Pemetrexed Transport and on Antifolates Activities Compared with the Reduced Folate Carrier
- (2008) R. Zhao et al. MOLECULAR PHARMACOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now