In vivo and in vitro reconstitution of unique key steps in cystobactamid antibiotic biosynthesis

Cystobactamid 507: Concise Synthesis, Mode of Action and Optimization toward More Potent Antibiotics

(2020) Walid A. M. Elgaher et al.   CHEMISTRY-A EUROPEAN JOURNAL

Coralmycin Derivatives with Potent Anti-Gram Negative Activity Produced by the Myxobacteria Corallococcus coralloides M23

(2019) Bo-Min Kim et al.   MOLECULES

Scalable Syntheses of Methoxyaspartate and Preparation of the Antibiotic Cystobactamid 861-2 and Highly Potent Derivatives

(2019) Malte Moeller et al.   ORGANIC LETTERS

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

(2018) Evelina Tacconelli et al.   LANCET INFECTIOUS DISEASES

Synthetic biology approaches and combinatorial biosynthesis towards heterologous lipopeptide production

(2018) Fu Yan et al.   Chemical Science

Biosynthesis of Branched Alkoxy Groups: Iterative Methyl Group Alkylation by a Cobalamin-Dependent Radical SAM Enzyme

(2017) Yuanyou Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Natural products from myxobacteria: novel metabolites and bioactivities

(2017) J. Herrmann et al.   NATURAL PRODUCT REPORTS

Transformation-associated recombination (TAR) cloning for genomics studies and synthetic biology

(2016) Natalay Kouprina et al.   CHROMOSOMA

The B12-Radical SAM Enzyme PoyC Catalyzes Valine Cβ-Methylation during Polytheonamide Biosynthesis

(2016) Aubérie Parent et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A structural model for multimodular NRPS assembly lines

(2016) Mohamed A. Marahiel   NATURAL PRODUCT REPORTS

The gyrase inhibitor albicidin consists of p-aminobenzoic acids and cyanoalanine

(2015) Stéphane Cociancich et al.   Nature Chemical Biology

Synthesis and Biological Evaluation of Cystobactamid 507: A Bacterial Topoisomerase Inhibitor from Cystobacter sp.

(2015) Andreas Kirschning et al.   SYNLETT

Cystobactamids: Myxobacterial Topoisomerase Inhibitors Exhibiting Potent Antibacterial Activity

(2014) Sascha Baumann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonproteinogenic Amino Acid Building Blocks for Nonribosomal Peptide and Hybrid Polyketide Scaffolds

(2013) Christopher T. Walsh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biochemical Determination of Enzyme-Bound Metabolites: Preferential Accumulation of a Programmed Octaketide on the Enediyne Polyketide Synthase CalE8

(2013) Katherine Belecki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Basis of the Interaction of MbtH-like Proteins, Putative Regulators of Nonribosomal Peptide Biosynthesis, with Adenylating Enzymes

(2012) Dominik A. Herbst et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aminomutases: mechanistic diversity, biotechnological applications and future perspectives

(2011) Bian Wu et al.   TRENDS IN BIOTECHNOLOGY

Discovery of Additional Members of the Tyrosine Aminomutase Enzyme Family and the Mutational Analysis of CmdF

(2009) Daniel Krug et al.   CHEMBIOCHEM

β-Hydroxylation of the Aspartyl Residue in the Phytotoxin Syringomycin E: Characterization of Two Candidate Hydroxylases AspH and SyrP inPseudomonas syringae†

(2008) Gitanjali M. Singh et al.   BIOCHEMISTRY

The Radical SAM Superfamily

(2008) Perry A. Frey et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

A simple and efficient expression and purification system using two newly constructed vectors

(2008) Huanting Liu et al.   PROTEIN EXPRESSION AND PURIFICATION