SOX2 promotes chemoresistance, cancer stem cells properties, and epithelial–mesenchymal transition by β-catenin and Beclin1/autophagy signaling in colorectal cancer

Regulation of cancer stem cell properties, angiogenesis, and vasculogenic mimicry by miR-450a-5p/SOX2 axis in colorectal cancer

(2020) Jiaxuan Chen et al.   Cell Death & Disease

CTCF promotes colorectal cancer cell proliferation and chemotherapy resistance to 5-FU via the P53-Hedgehog axis

(2020) Qiuhua Lai et al.   Aging-US

Cancer stem cell secretome in the tumor microenvironment: a key point for an effective personalized cancer treatment

(2020) Julia López de Andrés et al.   Journal of Hematology & Oncology

Transcriptional Regulation of Wnt/β-Catenin Pathway in Colorectal Cancer

(2020) Jia Bian et al.   Cells

TRAF6 inhibits colorectal cancer metastasis through regulating selective autophagic CTNNB1/β-catenin degradation and is targeted for GSK3B/GSK3β-mediated phosphorylation and degradation

(2019) Hua Wu et al.   Autophagy

Role of ATP-binding cassette transporters in cancer initiation and progression

(2019) Stefania Nobili et al.   SEMINARS IN CANCER BIOLOGY

Mitigating SOX2-potentiated Immune Escape of Head and Neck Squamous Cell Carcinoma with a STING-inducing Nanosatellite Vaccine

(2018) Yee Sun Tan et al.   CLINICAL CANCER RESEARCH

Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells

(2018) Qing Fan et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Autophagy inhibition reduces chemoresistance and tumorigenic potential of human ovarian cancer stem cells

(2017) Anna Pagotto et al.   Cell Death & Disease

Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3

(2016) Marina N. Sharifi et al.   Cell Reports

The modulation of ABC transporter-mediated multidrug resistance in cancer: A review of the past decade

(2015) Rishil J. Kathawala et al.   DRUG RESISTANCE UPDATES

Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine

(2015) Ming-Chen Yang et al.   Molecular Cancer

Inhibition of ABCB1 Overcomes Cancer Stem Cell-like Properties and Acquired Resistance to MET Inhibitors in Non-Small Cell Lung Cancer

(2015) T. Sugano et al.   MOLECULAR CANCER THERAPEUTICS

ABCB5 Maintains Melanoma-Initiating Cells through a Proinflammatory Cytokine Signaling Circuit

(2014) B. J. Wilson et al.   CANCER RESEARCH

Sox2 Is Required to Maintain Cancer Stem Cells in a Mouse Model of High-Grade Oligodendroglioma

(2014) Rebecca Favaro et al.   CANCER RESEARCH

Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF

(2014) Jurian Schuijers et al.   EMBO JOURNAL

Beclin 1 Expression is Closely Linked to Colorectal Carcinogenesis and Distant Metastasis of Colorectal Carcinoma

(2014) Mei-Ying Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Overexpression of SOX2 promotes migration, invasion, and epithelial-mesenchymal transition through the Wnt/β-catenin pathway in laryngeal cancer Hep-2 cells

(2014) Ning Yang et al.   TUMOR BIOLOGY

SOX2 promotes tumor metastasis by stimulating epithelial-to-mesenchymal transition via regulation of WNT/β-catenin signal network

(2013) Xuefei Li et al.   CANCER LETTERS

miR-23a inhibits E-cadherin expression and is regulated by AP-1 and NFAT4 complex during Fas-induced EMT in gastrointestinal cancer

(2013) Haoxuan Zheng et al.   CARCINOGENESIS

Transient Activation of Autophagy via Sox2-Mediated Suppression of mTOR Is an Important Early Step in Reprogramming to Pluripotency

(2013) Shuo Wang et al.   Cell Stem Cell

Sox2 promotes tamoxifen resistance in breast cancer cells

(2013) Marco Piva et al.   EMBO Molecular Medicine

Induction of acquired drug resistance in endothelial cells and its involvement in anticancer therapy

(2013) Limin Huang et al.   Journal of Hematology & Oncology

Study of chemoresistant CD133+ cancer stem cells from human glioblastoma cell line U138MG using multiple assays

(2012) Sudha Warrier et al.   CELL BIOLOGY INTERNATIONAL

Fas signaling promotes motility and metastasis through epithelial–mesenchymal transition in gastrointestinal cancer

(2012) H X Zheng et al.   ONCOGENE

ID4 Imparts Chemoresistance and Cancer Stemness to Glioma Cells by Derepressing miR-9*-Mediated Suppression of SOX2

(2011) H.-M. Jeon et al.   CANCER RESEARCH

Multidrug Efflux Pumps and Cancer Stem Cells: Insights Into Multidrug Resistance and Therapeutic Development

(2011) K Moitra et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

(2011) J. Y. Guo et al.   GENES & DEVELOPMENT

Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas

(2011) U Basu-Roy et al.   ONCOGENE

Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome

(2010) Motofumi Tanaka et al.   CANCER

The Beclin 1–VPS34 complex – at the crossroads of autophagy and beyond

(2010) Sarah F. Funderburk et al.   TRENDS IN CELL BIOLOGY

Correlation of CD133, OCT4, and SOX2 in Rectal Cancer and Their Association with Distant Recurrence After Chemoradiotherapy

(2009) Susumu Saigusa et al.   ANNALS OF SURGICAL ONCOLOGY

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

(2009) Adam J Bass et al.   NATURE GENETICS

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

The Molecular Mechanism Governing the Oncogenic Potential of SOX2 in Breast Cancer

(2008) Yupeng Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY