Identification of Metabolically Quiescent Leishmania mexicana Parasites in Peripheral and Cured Dermal Granulomas Using Stable Isotope Tracing Imaging Mass Spectrometry

Th1-Th2 Cross-Regulation Controls Early Leishmania Infection in the Skin by Modulating the Size of the Permissive Monocytic Host Cell Reservoir

(2020) Matheus Batista Carneiro et al.   Cell Host & Microbe

Leishmaniasis immunopathology—impact on design and use of vaccines, diagnostics and drugs

(2020) Paul M. Kaye et al.   Seminars in Immunopathology

Both Pharmacokinetic Variability and Granuloma Heterogeneity Impact the Ability of the First-Line Antibiotics to Sterilize Tuberculosis Granulomas

(2020) Joseph M. Cicchese et al.   Frontiers in Pharmacology

M2-like, dermal macrophages are maintained via IL-4/CCL24–mediated cooperative interaction with eosinophils in cutaneous leishmaniasis

(2020) Sang Hun Lee et al.   Science Immunology

Immunometabolism of Leishmania granulomas

(2020) Eleanor C. Saunders et al.   IMMUNOLOGY AND CELL BIOLOGY

A Physiological Basis for Nonheritable Antibiotic Resistance

(2020) Mauricio H. Pontes et al.   mBio

A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites

(2019) M. Fleur Sernee et al.   Cell Host & Microbe

Protozoan persister-like cells and drug treatment failure

(2019) Michael P. Barrett et al.   NATURE REVIEWS MICROBIOLOGY

Detection of small molecule concentration gradients in ocular tissues and humours

(2019) Berin A. Boughton et al.   JOURNAL OF MASS SPECTROMETRY

Visualization of Mycobacterial Biomarkers and Tuberculosis Drugs in Infected Tissue by MALDI-MS Imaging

(2018) Landry Blanc et al.   ANALYTICAL CHEMISTRY

Leishmania parasitophorous vacuole membranes display phosphoinositides that create conditions for continuous Akt activation and a target for miltefosine in Leishmania infections.

(2018) Naixin Zhang et al.   CELLULAR MICROBIOLOGY

Histopathological and immunohistochemical characterisation of hepatic granulomas in Leishmania donovani-infected BALB/c mice: a time-course study

(2018) Francisco J. Salguero et al.   Parasites & Vectors

Stress-Induced Proliferation and Cell Cycle Plasticity of Intracellular Trypanosoma cruzi Amastigotes

(2018) Peter C. Dumoulin et al.   mBio

Arginine and Polyamines Fate in Leishmania Infection

(2018) Sandra M. Muxel et al.   Frontiers in Microbiology

Hypoxia, Hypoxia-Inducible Factor-1α, and Innate Antileishmanial Immune Responses

(2018) Valentin Schatz et al.   Frontiers in Immunology

Diffuse Intralobular Liver Fibrosis in Dogs Naturally Infected with Leishmania (Leishmania) chagasi

(2018) Ferdinan Melo et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

A Metabolism-Based Quorum Sensing Mechanism Contributes to Termination of Inflammatory Responses

(2018) Jérémy Postat et al.   IMMUNITY

Leishmaniasis

(2018) Sakib Burza et al.   LANCET

Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair

(2018) Shuang Zhang et al.   Cell Metabolism

CD11c-expressing Ly6C+CCR2+ monocytes constitute a reservoir for efficient Leishmania proliferation and cell-to-cell transmission

(2018) Sandrina Heyde et al.   PLoS Pathogens

Frontline Science: Leishmania mexicana amastigotes can replicate within neutrophils

(2017) Benjamin P. Hurrell et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Continual renewal and replication of persistentLeishmania majorparasites in concomitantly immune hosts

(2017) Michael A. Mandell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased miltefosine tolerance in clinical isolates of Leishmania donovani is associated with reduced drug accumulation, increased infectivity and resistance to oxidative stress

(2017) Deepak Kumar Deep et al.   PLoS Neglected Tropical Diseases

Divergent roles for Ly6C+CCR2+CX3CR1+ inflammatory monocytes during primary or secondary infection of the skin with the intra-phagosomal pathogen Leishmania major

(2017) Audrey Romano et al.   PLoS Pathogens

Leishmania (Viannia) braziliensis Inositol Phosphorylceramide: Distinctive Sphingoid Base Composition

(2017) Erica V. De Castro Levatti et al.   Frontiers in Microbiology

Trypanosoma brucei Parasites Occupy and Functionally Adapt to the Adipose Tissue in Mice

(2016) Sandra Trindade et al.   Cell Host & Microbe

In Vitro and In Vivo Miltefosine Susceptibility of a Leishmania amazonensis Isolate from a Patient with Diffuse Cutaneous Leishmaniasis: Follow-Up

(2016) Adriano C. Coelho et al.   PLoS Neglected Tropical Diseases

Heterogeneous Host-Pathogen Encounters: Act Locally, Think Globally

(2015) Dirk Bumann   Cell Host & Microbe

Stress and Host Immunity Amplify Mycobacterium tuberculosis Phenotypic Heterogeneity and Induce Nongrowing Metabolically Active Forms

(2015) Giulia Manina et al.   Cell Host & Microbe

Cutaneous Na+ Storage Strengthens the Antimicrobial Barrier Function of the Skin and Boosts Macrophage-Driven Host Defense

(2015) Jonathan Jantsch et al.   Cell Metabolism

Lessons from other diseases: granulomatous inflammation in leishmaniasis

(2015) Paul M. Kaye et al.   Seminars in Immunopathology

Characterization of Metabolically Quiescent Leishmania Parasites in Murine Lesions Using Heavy Water Labeling

(2015) Joachim Kloehn et al.   PLoS Pathogens

Phenotypic Variation of Salmonella in Host Tissues Delays Eradication by Antimicrobial Chemotherapy

(2014) Beatrice Claudi et al.   CELL

Treatment failure in leishmaniasis: drug-resistance or another (epi-) phenotype?

(2014) Manu Vanaerschot et al.   Expert Review of Anti-Infective Therapy

Failure of Miltefosine in Visceral Leishmaniasis Is Associated With Low Drug Exposure

(2014) T. P. C. Dorlo et al.   JOURNAL OF INFECTIOUS DISEASES

Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters

(2014) S. Helaine et al.   SCIENCE

Induction of a Stringent Metabolic Response in Intracellular Stages of Leishmania mexicana Leads to Increased Dependence on Mitochondrial Metabolism

(2014) Eleanor C. Saunders et al.   PLoS Pathogens

Photoconvertible Pathogen Labeling Reveals Nitric Oxide Control of Leishmania major Infection In Vivo via Dampening of Parasite Metabolism

(2013) Andreas J. Müller et al.   Cell Host & Microbe

Microbial Persistence and the Road to Drug Resistance

(2013) Nadia R. Cohen et al.   Cell Host & Microbe

Relapse after Treatment with Miltefosine for Visceral Leishmaniasis Is Associated with Increased Infectivity of the Infecting Leishmania donovani Strain

(2013) K. Rai et al.   mBio

Mass spectrometry imaging for in situ kinetic histochemistry

(2013) Katherine B. Louie et al.   Scientific Reports

Leishmaniasis Worldwide and Global Estimates of Its Incidence

(2012) Jorge Alvar et al.   PLoS One

Clinical pleiomorphism in human leishmaniases, with special mention of asymptomatic infection

(2011) A.L. Bañuls et al.   CLINICAL MICROBIOLOGY AND INFECTION

Tissue granuloma structure-function in experimental visceral leishmaniasis

(2003) Henry W. Murray   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY