Respiratory mucus as a virus-host range determinant

Modified sialic acids on mucus and erythrocytes inhibit influenza A HA and NA functions

(2020) Karen N. Barnard et al.   JOURNAL OF VIROLOGY

Nasal mucus proteome and its involvement in allergic rhinitis

(2020) Peter Valentin Tomazic et al.   Expert Review of Proteomics

Airway Exosomes Released During Influenza Virus Infection Serve as a Key Component of the Antiviral Innate Immune Response

(2020) James G. Bedford et al.   Frontiers in Immunology

Coronavirus hemagglutinin-esterase and spike proteins coevolve for functional balance and optimal virion avidity

(2020) Yifei Lang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The SARS-COV-2 Spike Protein Binds Sialic Acids and Enables Rapid Detection in a Lateral Flow Point of Care Diagnostic Device

(2020) Alexander N. Baker et al.   ACS Central Science

Second sialic acid‐binding site of influenza A virus neuraminidase: binding receptors for efficient release

(2020) Wenjuan Du et al.   FEBS Journal

Virus recognition of glycan receptors

(2019) Andrew J Thompson et al.   Current Opinion in Virology

Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain A

(2019) Ruben J. G. Hulswit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influenza A virus surface proteins are organized to help penetrate host mucus

(2019) Michael D Vahey et al.   eLife

Structural basis for human coronavirus attachment to sialic acid receptors

(2019) M. Alejandra Tortorici et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses

(2019) Frederik Broszeit et al.   Cell Reports

Influenza A Virus Hemagglutinin–Neuraminidase–Receptor Balance: Preserving Virus Motility

(2019) Erik de Vries et al.   TRENDS IN MICROBIOLOGY

Towards the Application of Human Defensins as Antivirals

(2018) Mee Sook Park et al.   Biomolecules & Therapeutics

Selective permeability of mucus barriers

(2018) Jacob Witten et al.   CURRENT OPINION IN BIOTECHNOLOGY

Receptor-binding properties of influenza viruses isolated from gulls

(2018) Alexandra S. Gambaryan et al.   VIROLOGY

Kinetic analysis of the influenza A virus HA/NA balance reveals contribution of NA to virus-receptor binding and NA-dependent rolling on receptor-containing surfaces

(2018) Hongbo Guo et al.   PLoS Pathogens

Phylogenetic Distribution of CMP-Neu5Ac Hydroxylase (CMAH), the Enzyme Synthetizing the Proinflammatory Human Xenoantigen Neu5Gc

(2017) Sateesh Peri et al.   Genome Biology and Evolution

The Interplay between the Host Receptor and Influenza Virus Hemagglutinin and Neuraminidase

(2017) Lauren Byrd-Leotis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Physicochemical properties of mucus and their impact on transmucosal drug delivery

(2017) Jasmim Leal et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

An innate defense peptide BPIFA1/SPLUNC1 restricts influenza A virus infection

(2017) K M Akram et al.   Mucosal Immunology

Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein

(2017) Wentao Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distribution of O-Acetylated Sialic Acids among Target Host Tissues for Influenza Virus

(2017) Brian R. Wasik et al.   mSphere

Proteome analysis of bronchoalveolar lavage from calves infected with bovine respiratory syncytial virus—Insights in pathogenesis and perspectives for new treatments

(2017) Sara Hägglund et al.   PLoS One

Influenza A virus hemagglutinin and neuraminidase act as novel motile machinery

(2017) Tatsuya Sakai et al.   Scientific Reports

The Interaction between Respiratory Pathogens and Mucus

(2016) Mark Zanin et al.   Cell Host & Microbe

Characterization of the Adeno-Associated Virus 1 and 6 Sialic Acid Binding Site

(2016) Lin-Ya Huang et al.   JOURNAL OF VIROLOGY

Enterovirus D68 receptor requirements unveiled by haploid genetics

(2016) Jim Baggen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Sialic Acid Modifications on Virus Binding and Infection

(2016) Brian R. Wasik et al.   TRENDS IN MICROBIOLOGY

What adaptive changes in hemagglutinin and neuraminidase are necessary for emergence of pandemic influenza virus from its avian precursor?

(2015) A. S. Gambaryan et al.   BIOCHEMISTRY-MOSCOW

Pandemic Swine H1N1 Influenza Viruses with Almost Undetectable Neuraminidase Activity Are Not Transmitted via Aerosols in Ferrets and Are Inhibited by Human Mucus but Not Swine Mucus

(2015) Mark Zanin et al.   JOURNAL OF VIROLOGY

Proteomic Analysis of Pure Human Airway Gland Mucus Reveals a Large Component of Protective Proteins

(2015) Nam Soo Joo et al.   PLoS One

Complexity and Diversity of the Mammalian Sialome Revealed by Nidovirus Virolectins

(2015) Martijn A. Langereis et al.   Cell Reports

One-way trip: Influenza virus' adaptation to gallinaceous poultry may limit its pandemic potential

(2014) Jason S. Long et al.   BIOESSAYS

Role of receptor binding specificity in influenza A virus transmission and pathogenesis

(2014) M. de Graaf et al.   EMBO JOURNAL

Parallel evolution of a self-signal: humans and new world monkeys independently lost the cell surface sugar Neu5Gc

(2014) Stevan A. Springer et al.   IMMUNOGENETICS

Glycomic Characterization of Respiratory Tract Tissues of Ferrets

(2014) Nan Jia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lactoferrin for prevention of common viral infections

(2014) Hiroyuki Wakabayashi et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Terminal sialic acid linkages determine different cell infectivities of human parainfluenza virus type 1 and type 3

(2014) Keijo Fukushima et al.   VIROLOGY

A chicken influenza virus recognizes fucosylated α2,3 sialoglycan receptors on the epithelial cells lining upper respiratory tracts of chickens

(2014) Takahiro Hiono et al.   VIROLOGY

Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors

(2014) Preston S.K. Ng et al.   Nature Communications

Protein composition of bronchoalveolar lavage fluid and airway surface liquid from newborn pigs

(2013) Jennifer A. Bartlett et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Infection of swineex vivotissues with avian viruses including H7N9 and correlation with glycomic analysis

(2013) Renee W. Y. Chan et al.   Influenza and Other Respiratory Viruses

Influenza A penetrates host mucus by cleaving sialic acids with neuraminidase

(2013) Miriam Cohen et al.   Virology Journal

α2-3- and α2-6- N-linked sialic acids allow efficient interaction of Newcastle Disease Virus with target cells

(2012) Lorena Sánchez-Felipe et al.   GLYCOCONJUGATE JOURNAL

The human cathelicidin LL-37 inhibits influenza A viruses through a mechanism distinct from that of surfactant protein D or defensins

(2012) S. Tripathi et al.   JOURNAL OF GENERAL VIROLOGY

Immobilization of Pseudorabies Virus in Porcine Tracheal Respiratory Mucus Revealed by Single Particle Tracking

(2012) Xiaoyun Yang et al.   PLoS One

A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia

(2012) B. Button et al.   SCIENCE

Insight into Glycan Diversity and Evolutionary Lineage Based on Comparative Avio-N-glycomics and Sialic Acid Analysis of 88 Egg Whites of Galloanserae

(2011) Kazuko Hirose et al.   BIOCHEMISTRY

Lectin-based structural glycomics: A practical approach to complex glycans

(2011) Jun Hirabayashi et al.   ELECTROPHORESIS

Galectin-1 Binds to Influenza Virus and Ameliorates Influenza Virus Pathogenesis

(2011) M.-L. Yang et al.   JOURNAL OF VIROLOGY

N-Glycans from Porcine Trachea and Lung: Predominant NeuAcα2-6Gal Could Be a Selective Pressure for Influenza Variants in Favor of Human-Type Receptor

(2011) Nongluk Sriwilaijaroen et al.   PLoS One

Deleted in Malignant Brain Tumors-1 Protein (DMBT1): A Pattern Recognition Receptor with Multiple Binding Sites

(2010) Antoon J. M. Ligtenberg et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glycan Analysis and Influenza A Virus Infection of Primary Swine Respiratory Epithelial Cells

(2010) Allen C. Bateman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Airway Mucus Function and Dysfunction

(2010) John V. Fahy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense

(2009) Mehmet Kesimer et al.   FASEB JOURNAL