The Interplay between the Host Receptor and Influenza Virus Hemagglutinin and Neuraminidase

Role of Neuraminidase in Influenza A(H7N9) Virus Receptor Binding

(2017) Donald J. Benton et al.   JOURNAL OF VIROLOGY

Global environmental drivers of influenza

(2016) Ethan R. Deyle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biophysical Measurement of the Balance of Influenza A Hemagglutinin and Neuraminidase Activities

(2015) Donald J. Benton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influenza Hemagglutinin (HA) Stem Region Mutations That Stabilize or Destabilize the Structure of Multiple HA Subtypes

(2015) Lauren Byrd-Leotis et al.   JOURNAL OF VIROLOGY

Hemagglutinin-Neuraminidase Balance Influences the Virulence Phenotype of a Recombinant H5N3 Influenza A Virus Possessing a Polybasic HA0Cleavage Site

(2015) Sandra Diederich et al.   JOURNAL OF VIROLOGY

Pandemic Swine H1N1 Influenza Viruses with Almost Undetectable Neuraminidase Activity Are Not Transmitted via Aerosols in Ferrets and Are Inhibited by Human Mucus but Not Swine Mucus

(2015) Mark Zanin et al.   JOURNAL OF VIROLOGY

Expected and Unexpected Features of the Newly Discovered Bat Influenza A-like Viruses

(2015) Wenjun Ma et al.   PLoS Pathogens

Residue 41 of the Eurasian Avian-Like Swine Influenza A Virus Matrix Protein Modulates Virion Filament Length and Efficiency of Contact Transmission

(2014) P. J. Campbell et al.   JOURNAL OF VIROLOGY

Introductions and Evolution of Human-Origin Seasonal Influenza A Viruses in Multinational Swine Populations

(2014) M. I. Nelson et al.   JOURNAL OF VIROLOGY

The M Segment of the 2009 Pandemic Influenza Virus Confers Increased Neuraminidase Activity, Filamentous Morphology, and Efficient Contact Transmissibility to A/Puerto Rico/8/1934-Based Reassortant Viruses

(2014) P. J. Campbell et al.   JOURNAL OF VIROLOGY

Filament-Producing Mutants of Influenza A/Puerto Rico/8/1934 (H1N1) Virus Have Higher Neuraminidase Activities than the Spherical Wild-Type

(2014) Jill Seladi-Schulman et al.   PLoS One

Shotgun glycomics of pig lung identifies natural endogenous receptors for influenza viruses

(2014) L. Byrd-Leotis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced human receptor binding by H5 haemagglutinins

(2014) Xiaoli Xiong et al.   VIROLOGY

Glycan Receptor Binding of the Influenza A Virus H7N9 Hemagglutinin

(2013) Kannan Tharakaraman et al.   CELL

Infection of swineex vivotissues with avian viruses including H7N9 and correlation with glycomic analysis

(2013) Renee W. Y. Chan et al.   Influenza and Other Respiratory Viruses

Hemagglutinin Receptor Specificity and Structural Analyses of Respiratory Droplet-Transmissible H5N1 Viruses

(2013) R. P. de Vries et al.   JOURNAL OF VIROLOGY

Spherical Influenza Viruses Have a Fitness Advantage in Embryonated Eggs, while Filament-Producing Strains Are Selected In Vivo

(2013) J. Seladi-Schulman et al.   JOURNAL OF VIROLOGY

Increased Acid Stability of the Hemagglutinin Protein Enhances H5N1 Influenza Virus Growth in the Upper Respiratory Tract but Is Insufficient for Transmission in Ferrets

(2013) H. Zaraket et al.   JOURNAL OF VIROLOGY

Pathways to human adaptation

(2013) David A. Steinhauer   NATURE

Receptor binding by a ferret-transmissible H5 avian influenza virus

(2013) Xiaoli Xiong et al.   NATURE

Pathogenesis and transmission of avian influenza A (H7N9) virus in ferrets and mice

(2013) Jessica A. Belser et al.   NATURE

Receptor binding by an H7N9 influenza virus from humans

(2013) Xiaoli Xiong et al.   NATURE

Biological features of novel avian influenza A (H7N9) virus

(2013) Jianfang Zhou et al.   NATURE

Characterization of H7N9 influenza A viruses isolated from humans

(2013) Tokiko Watanabe et al.   NATURE

Muc5b is required for airway defence

(2013) Michelle G. Roy et al.   NATURE

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Infectivity, Transmission, and Pathology of Human-Isolated H7N9 Influenza Virus in Ferrets and Pigs

(2013) H. Zhu et al.   SCIENCE

Structures and Receptor Binding of Hemagglutinins from Human-Infecting H7N9 Influenza Viruses

(2013) Y. Shi et al.   SCIENCE

Influenza A penetrates host mucus by cleaving sialic acids with neuraminidase

(2013) Miriam Cohen et al.   Virology Journal

Glycomic Analysis of Human Respiratory Tract Tissues and Correlation with Influenza Virus Infection

(2013) Trevenan Walther et al.   PLoS Pathogens

New World Bats Harbor Diverse Influenza A Viruses

(2013) Suxiang Tong et al.   PLoS Pathogens

Influenza HA Subtypes Demonstrate Divergent Phenotypes for Cleavage Activation and pH of Fusion: Implications for Host Range and Adaptation

(2013) Summer E. Galloway et al.   PLoS Pathogens

Structure and receptor-binding properties of an airborne transmissible avian influenza A virus hemagglutinin H5 (VN1203mut)

(2013) Xishan Lu et al.   Protein & Cell

Expression and distribution of sialic acid influenza virus receptors in wild birds

(2012) M. França et al.   AVIAN PATHOLOGY

Functional Balance of the Hemagglutinin and Neuraminidase Activities Accompanies the Emergence of the 2009 H1N1 Influenza Pandemic

(2012) R. Xu et al.   JOURNAL OF VIROLOGY

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

(2012) Masaki Imai et al.   NATURE

Rescue of a H3N2 Influenza Virus Containing a Deficient Neuraminidase Protein by a Hemagglutinin with a Low Receptor-Binding Affinity

(2012) Mathilde Richard et al.   PLoS One

Evolution of the receptor binding properties of the influenza A(H3N2) hemagglutinin

(2012) Y. P. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpressing mouse model demonstrates the protective role of Muc5ac in the lungs

(2012) C. Ehre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A distinct lineage of influenza A virus from bats

(2012) S. Tong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influenza A virus entry into cells lacking sialylated N-glycans

(2012) E. de Vries et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia

(2012) B. Button et al.   SCIENCE

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

(2012) S. Herfst et al.   SCIENCE

Letter to the Glyco-Forum: Effective glycoanalysis with Maackia amurensis lectins requires a clear understanding of their binding specificities

(2011) C. Geisler et al.   GLYCOBIOLOGY

A Sialylated Glycan Microarray Reveals Novel Interactions of Modified Sialic Acids with Proteins and Viruses

(2011) Xuezheng Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of Influenza Virus Hemagglutinin Receptor Binding Mutants with Limited Receptor Recognition Properties and Conditional Replication Characteristics

(2011) K. C. Bradley et al.   JOURNAL OF VIROLOGY

Amino Acid Changes in Hemagglutinin Contribute to the Replication of Oseltamivir-Resistant H1N1 Influenza Viruses

(2011) T. E. Ginting et al.   JOURNAL OF VIROLOGY

Emergence and Genetic Variation of Neuraminidase Stalk Deletions in Avian Influenza Viruses

(2011) Jinling Li et al.   PLoS One

N-Glycans from Porcine Trachea and Lung: Predominant NeuAcα2-6Gal Could Be a Selective Pressure for Influenza Variants in Favor of Human-Type Receptor

(2011) Nongluk Sriwilaijaroen et al.   PLoS One

Infection of Differentiated Porcine Airway Epithelial Cells by Influenza Virus: Differential Susceptibility to Infection by Porcine and Avian Viruses

(2011) Darsaniya Punyadarsaniya et al.   PLoS One

Hemagglutinin-neuraminidase balance confers respiratory-droplet transmissibility of the pandemic H1N1 influenza virus in ferrets

(2011) H.-L. Yen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of receptor binding domain mutations on receptor binding and transmissibility of avian influenza H5N1 viruses

(2011) Taronna R. Maines et al.   VIROLOGY

Comparison of the receptor binding properties of contemporary swine isolates and early human pandemic H1N1 isolates (Novel 2009 H1N1)

(2011) Konrad C. Bradley et al.   VIROLOGY

Receptor specificity of subtype H1 influenza A viruses isolated from swine and humans in the United States

(2011) Li-Mei Chen et al.   VIROLOGY

Distribution of sialic acid receptors and influenza A virus of avian and swine origin in experimentally infected pigs

(2011) Ramona Trebbien et al.   Virology Journal

Acquisition of Human-Type Receptor Binding Specificity by New H5N1 Influenza Virus Sublineages during Their Emergence in Birds in Egypt

(2011) Yohei Watanabe et al.   PLoS Pathogens

Eurasian-Origin Gene Segments Contribute to the Transmissibility, Aerosol Release, and Morphology of the 2009 Pandemic H1N1 Influenza Virus

(2011) Seema S. Lakdawala et al.   PLoS Pathogens

Comparative distribution of human and avian type sialic acid influenza receptors in the pig

(2010) Rahul K Nelli et al.   BMC Veterinary Research

Glycan Analysis and Influenza A Virus Infection of Primary Swine Respiratory Epithelial Cells

(2010) Allen C. Bateman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered Receptor Specificity and Cell Tropism of D222G Hemagglutinin Mutants Isolated from Fatal Cases of Pandemic A(H1N1) 2009 Influenza Virus

(2010) Y. Liu et al.   JOURNAL OF VIROLOGY

Receptor Binding Profiles of Avian Influenza Virus Hemagglutinin Subtypes on Human Cells as a Predictor of Pandemic Potential

(2010) H. Shelton et al.   JOURNAL OF VIROLOGY

Virulence-Associated Substitution D222G in the Hemagglutinin of 2009 Pandemic Influenza A(H1N1) Virus Affects Receptor Binding

(2010) S. Chutinimitkul et al.   JOURNAL OF VIROLOGY

Receptor Specificity of Influenza A H3N2 Viruses Isolated in Mammalian Cells and Embryonated Chicken Eggs

(2010) J. Stevens et al.   JOURNAL OF VIROLOGY

Shotgun glycomics: a microarray strategy for functional glycomics

(2010) Xuezheng Song et al.   NATURE METHODS

Determinants of Glycan Receptor Specificity of H2N2 Influenza A Virus Hemagglutinin

(2010) Karthik Viswanathan et al.   PLoS One

Structural organization of a filamentous influenza A virus

(2010) L. J. Calder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Replication of avian, human and swine influenza viruses in porcine respiratory explants and association with sialic acid distribution

(2010) Sjouke GM Van Poucke et al.   Virology Journal

Characterization of influenza virus sialic acid receptors in minor poultry species

(2010) Brian Kimble et al.   Virology Journal

Alterations in receptor-binding properties of swine influenza viruses of the H1 subtype after isolation in embryonated chicken eggs

(2009) N. Takemae et al.   JOURNAL OF GENERAL VIROLOGY

Structure, Receptor Binding, and Antigenicity of Influenza Virus Hemagglutinins from the 1957 H2N2 Pandemic

(2009) R. Xu et al.   JOURNAL OF VIROLOGY

Receptor-binding specificity of pandemic influenza A (H1N1) 2009 virus determined by carbohydrate microarray

(2009) Robert A Childs et al.   NATURE BIOTECHNOLOGY

Structures of receptor complexes formed by hemagglutinins from the Asian Influenza pandemic of 1957

(2009) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transmission and Pathogenesis of Swine-Origin 2009 A(H1N1) Influenza Viruses in Ferrets and Mice

(2009) Taronna R. Maines et al.   SCIENCE

Adaptation and transmission of a duck-origin avian influenza virus in poultry species

(2009) Jinling Li et al.   VIRUS RESEARCH

Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N

(2009) John Steel et al.   PLoS Pathogens

Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness

(2008) David M. Morens et al.   JOURNAL OF INFECTIOUS DISEASES