Principles of membrane remodeling by dynamic ESCRT-III polymers

Membrane constriction and thinning by sequential ESCRT-III polymerization

(2020) Henry C. Nguyen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Anisotropic ESCRT-III architecture governs helical membrane tube formation

(2020) Joachim Moser von Filseck et al.   Nature Communications

Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation

(2020) Aurélie Bertin et al.   Nature Communications

An ESCRT-III Polymerization Sequence Drives Membrane Deformation and Fission

(2020) Anna-Katharina Pfitzner et al.   CELL

The proteasome controls ESCRT-III–mediated cell division in an archaeon

(2020) Gabriel Tarrason Risa et al.   SCIENCE

Structure and assembly of ESCRT-III helical Vps24 filaments

(2020) Stefan T. Huber et al.   Science Advances

The role of VPS4 in ESCRT-III polymer remodeling

(2019) Christophe Caillat et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

VPS4 triggers constriction and cleavage of ESCRT-III helical filaments

(2019) Sourav Maity et al.   Science Advances

Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III

(2019) Chi-Lun Chang et al.   JOURNAL OF CELL BIOLOGY

Structure of Vps4 with circular peptides and implications for translocation of two polypeptide chains by AAA+ ATPases

(2019) Han Han et al.   eLife

Electrostatic lateral interactions drive ESCRT-III heteropolymer assembly

(2019) Sudeep Banjade et al.   eLife

The ESCRT-machinery: closing holes and expanding roles

(2019) Alberto T Gatta et al.   CURRENT OPINION IN CELL BIOLOGY

Changes in ESCRT-III filament geometry drive membrane remodelling and fission in silico

(2019) Lena Harker-Kirschneck et al.   BMC BIOLOGY

The many functions of ESCRTs

(2019) Marina Vietri et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ESCRT-III is required for scissioning new peroxisomes from the endoplasmic reticulum

(2018) Fred D. Mast et al.   JOURNAL OF CELL BIOLOGY

Mechanisms of clathrin-mediated endocytosis

(2018) Marko Kaksonen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Resolving ESCRT-III Spirals at the Intercellular Bridge of Dividing Cells Using 3D STORM

(2018) Inna Goliand et al.   Cell Reports

Dynamic subunit turnover in ESCRT-III assemblies is regulated by Vps4 to mediate membrane remodelling during cytokinesis

(2017) Beata E. Mierzwa et al.   NATURE CELL BIOLOGY

Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding

(2017) Manuel Alonso Y Adell et al.   eLife

Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase

(2017) Nicole Monroe et al.   eLife

Reverse-topology membrane scission by the ESCRT proteins

(2016) Johannes Schöneberg et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Electrostatic Interactions between Elongated Monomers Drive Filamentation of Drosophila Shrub, a Metazoan ESCRT-III Protein

(2016) Brian J. McMillan et al.   Cell Reports

Relaxation of Loaded ESCRT-III Spiral Springs Drives Membrane Deformation

(2015) Nicolas Chiaruttini et al.   CELL

Binding of Substrates to the Central Pore of the Vps4 ATPase Is Autoinhibited by the Microtubule Interacting and Trafficking (MIT) Domain and Activated by MIT Interacting Motifs (MIMs)

(2015) Han Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation

(2015) Bei Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure and membrane remodeling activity of ESCRT-III helical polymers

(2015) J. McCullough et al.   SCIENCE

Asymmetric ring structure of Vps4 required for ESCRT-III disassembly

(2015) Christophe Caillat et al.   Nature Communications

Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation

(2015) Bei Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments

(2015) Shaogeng Tang et al.   eLife

Coordinated binding of Vps4 to ESCRT-III drives membrane neck constriction during MVB vesicle formation

(2014) Manuel Alonso Y Adell et al.   JOURNAL OF CELL BIOLOGY

Structural analysis and modeling reveals new mechanisms governing ESCRT-III spiral filament assembly

(2014) Qing-Tao Shen et al.   JOURNAL OF CELL BIOLOGY

Electron Tomography of HIV-1 Infection in Gut-Associated Lymphoid Tissue

(2014) Mark S. Ladinsky et al.   PLoS Pathogens

Structure of cellular ESCRT-III spirals and their relationship to HIV budding

(2014) Anil G Cashikar et al.   eLife

Essential N-Terminal Insertion Motif Anchors the ESCRT-III Filament during MVB Vesicle Formation

(2013) Nicholas J. Buchkovich et al.   DEVELOPMENTAL CELL

An ESCRT–spastin interaction promotes fission of recycling tubules from the endosome

(2013) Rachel Allison et al.   JOURNAL OF CELL BIOLOGY

The Oligomeric State of the Active Vps4 AAA ATPase

(2013) Nicole Monroe et al.   JOURNAL OF MOLECULAR BIOLOGY

The Endosomal Sorting Complex ESCRT-II Mediates the Assembly and Architecture of ESCRT-III Helices

(2012) William Mike Henne et al.   CELL

ESCRT-III CHMP2A and CHMP3 form variable helical polymersin vitroand act synergistically during HIV-1 budding

(2012) Grégory Effantin et al.   CELLULAR MICROBIOLOGY

ESCRT-III polymers in membrane neck constriction

(2012) Julien Guizetti et al.   TRENDS IN CELL BIOLOGY

Charged Multivesicular Body Protein 2B (CHMP2B) of the Endosomal Sorting Complex Required for Transport-III (ESCRT-III) Polymerizes into Helical Structures Deforming the Plasma Membrane

(2011) Gilles Bodon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cortical Constriction During Abscission Involves Helices of ESCRT-III-Dependent Filaments

(2011) J. Guizetti et al.   SCIENCE

Structural basis for ESCRT-III protein autoinhibition

(2009) Monika Bajorek et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Membrane Buckling Induced by Curved Filaments

(2009) Martin Lenz et al.   PHYSICAL REVIEW LETTERS

ESCRT-III Family Members Stimulate Vps4 ATPase Activity Directly or via Vta1

(2008) Ishara F. Azmi et al.   DEVELOPMENTAL CELL

Plasma membrane deformation by circular arrays of ESCRT-III protein filaments

(2008) Phyllis I. Hanson et al.   JOURNAL OF CELL BIOLOGY

Helical Structures of ESCRT-III Are Disassembled by VPS4

(2008) S. Lata et al.   SCIENCE

Structure and Disassembly of Filaments Formed by the ESCRT-III Subunit Vps24

(2008) Sara Ghazi-Tabatabai et al.   STRUCTURE